An alternative treatment approach for patients with resistant otitis media with effusion and dysfunctional Eustachian tube: A pilot study with rapid maxillary expansion

ABSTRACT Objectives To determine whether dysfunctional Eustachian tubes of children with resistant otitis media with effusion (OME), ventilation tube placement indication, and maxillary constriction will recover after rapid maxillary expansion (RME). Materials and Methods The RME group consisted of 15 children (mean age: 10.07 years) with maxillary constriction, Eustachian tube dysfunction (ETD), and resistant OME. The control group consisted of 11 healthy children (mean age: 8.34 years) with no orthodontic and/or rhinologic problems. Recovery of Eustachian tube dysfunction was evaluated by Williams' test at three timepoints: before RME/at baseline (T0); after RME (T1); and after an observation period of 10 months (T2). The control group was matched to all these periods, except T1. Results In the control group, functioning Eustachian tubes were observed in all ears at baseline (T0), and tubes showed no worsening and no change during the observation period (T2) (P > .05). In the RME group, functioning Eustachian tubes were observed in eight of 30 ears and ETD was observed in the remaining 22 ears at baseline (T0). The RME group showed significant improvements in tube functions after RME and the observation period (P < .05). Fifteen of 22 dysfunctional ears recovered (68.2%) and started to exhibit normal Eustachian tube function after RME (T1) and the observation period (T2). Conclusions The findings suggest that ears having poorly functioning Eustachian tubes are restored and recovered after RME in most of children with maxillary constriction and resistant OME. Thus, RME should be preferred as a first therapy alternative for children with maxillary constriction and serous otitis media.

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Relationship between Eustachian tube dysfunction and otitis media with effusion in radiotherapy patients

The Journal of Laryngology & Otology ◽

10.1017/s0022215118000014 ◽

2018 ◽

Vol 132 (2) ◽

pp. 111-116 ◽

Cited By ~ 6

Author(s):

K Akazawa ◽

H Doi ◽

S Ohta ◽

T Terada ◽

M Fujiwara ◽

...

Keyword(s):

Radiation Dose ◽

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Intensity Modulated Radiotherapy ◽

Eustachian Tube Dysfunction ◽

Dose Volume ◽

Tube Dysfunction ◽

The Relationship ◽

Higher Doses

AbstractObjective:This study evaluated the relationship between radiation and Eustachian tube dysfunction, and examined the radiation dose required to induce otitis media with effusion.Methods:The function of 36 Eustachian tubes in 18 patients with head and neck cancer were examined sonotubometrically before, during, and 1, 2 and 3 months after, intensity-modulated radiotherapy. Patients with an increase of 5 dB or less in sound pressure level (dB) during swallowing were categorised as being in the dysfunction group. Additionally, radiation dose distributions were assessed in all Eustachian tubes using three dose–volume histogram parameters.Results:Twenty-two of 25 normally functioning Eustachian tubes before radiotherapy (88.0 per cent) shifted to the dysfunction group after therapy. All ears that developed otitis media with effusion belonged to the dysfunction group. The radiation dose threshold evaluation revealed that ears with otitis media with effusion received significantly higher doses to the Eustachian tubes.Conclusion:The results indicate a relationship between radiation dose and Eustachian tube dysfunction and otitis media with effusion.

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Refractory otitis media with effusion from viewpoints of eustachian tube dysfunction and nasal sinusitis

American Journal of Otolaryngology ◽

10.1016/0196-0709(93)90028-6 ◽

1993 ◽

Vol 14 (3) ◽

pp. 187-190 ◽

Cited By ~ 20

Author(s):

Akihiko Fujita ◽

Iwao Honjo ◽

Kyosuke Kurata ◽

I-Ken Gan ◽

Haruo Takahashi

Keyword(s):

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Tube Dysfunction

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Immune Modulatory Oligonucleotides in the Prevention and Treatment of OVA-Induced Eustachian Tube Dysfunction in Rats

Otolaryngology ◽

10.1016/j.otohns.2007.02.016 ◽

2007 ◽

Vol 137 (2) ◽

pp. 321-326 ◽

Cited By ~ 5

Author(s):

Deidra A. Blanks ◽

Charles S. Ebert ◽

Rose P. Eapen ◽

Carlton Zdanski ◽

Ekambar R. Kandimalla ◽

...

Keyword(s):

Eustachian Tube ◽

Negative Pressure ◽

Mucociliary Clearance ◽

Otitis Media With Effusion ◽

Allergic Inflammation ◽

Eustachian Tube Dysfunction ◽

Brown Norway ◽

Control Group ◽

Prevention And Treatment ◽

Tube Dysfunction

BACKGROUND: Otitis media with effusion (OME) is often associated with allergies. Immune modulatory oligonucleotides (IMO) mediate allergic inflammation and may therefore be efficacious in the treatment of airway inflammation. OBJECTIVE: To evaluate the role of an IMO via transtympanic mucosal application in prevention and treatment of ovalbumin-induced OME. DESIGN: Forty brown Norway rats were divided into control and treatment groups. Eustachian tube dysfunction was evaluated by passive opening pressures, passive closing pressures, active clearance of negative pressure, and mucociliary clearance transit time. RESULTS: Rats who underwent IMO treatment required 50% less pressure to open and close the eustachian tube ( P < 0.05) and were able to actively clear 50% more negative pressure than the ovalbumin-control rats ( P < 0.001). The treatment rats' mucociliary clearance time was half that of the control group ( P < 0.001). CONCLUSION: IMO via transtympanic application can prevent and treat allergy-induced eustachian tube dysfunction in rats. IMO may offer substantial promise in the future management of OME.

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Rapid maxillary expansion versus middle ear tube placement: Comparison of hearing improvements in children with resistance otitis media with effusion

The Angle Orthodontist ◽

10.2319/101515-693.1 ◽

2016 ◽

Vol 86 (5) ◽

pp. 761-767 ◽

Cited By ~ 1

Author(s):

Nihat Kılıç ◽

Özgür Yörük ◽

Songül Cömert Kılıç ◽

Gülhan Çatal ◽

Sezgin Kurt

Keyword(s):

Otitis Media ◽

Null Hypothesis ◽

Otitis Media With Effusion ◽

Tube Placement ◽

Control Group ◽

Ventilation Tube ◽

Maxillary Expansion ◽

Control Groups ◽

Hearing Thresholds ◽

Maxillary Constriction

ABSTRACT Objective: To test the null hypothesis that there are significant differences in hearing improvements of children with resistance otitis media with effusion (OME) who undergo a rapid maxillary expansion (RME) procedure or ventilation tube placement. Methods: Forty-two children between 4.5 and 15 years old were divided into three groups: RME, ventilation tube, and control groups. The RME group consisted of 15 children with maxillary constriction and resistance OME that indicated ventilation tube placement. The ventilation tube group consisted of 16 children for whom ventilation tube placement was indicated but no maxillary constriction. The control group consisted of 11 children with no orthodontic and/or rhinologic problems. Hearing thresholds were evaluated with three audiometric records: (1) before RME/ventilation tube placement (T0); (2) after RME/ventilation tube placement (T1), and (3) after an observation period of 10 months (T2). The control group was matched to these periods, except T1. Results: Hearing thresholds decreased significantly in both the RME and ventilation tube groups (P < .001). Hearing thresholds decreased approximately 15 and 17 decibels in the RME and ventilation tube groups, respectively, but differences in improvements were insignificant between the two study groups (P > .05). Slight changes were observed in the control groups. Conclusion: The null hypothesis was rejected. RME showed similar effects as ventilation tube placement for release of otitis media and improvement of hearing thresholds levels. RME should be preferred as a first treatment option for children with maxillary constriction and resistance OME.

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An easier way of inserting the Shah permavent grommet

The Journal of Laryngology & Otology ◽

10.1258/0022215053222798 ◽

2005 ◽

Vol 119 (1) ◽

pp. 36-37 ◽

Cited By ~ 3

Author(s):

J Tahery ◽

S R Saeed

Keyword(s):

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Ventilation Tube ◽

Tube Insertion ◽

Simple Modification ◽

Tube Dysfunction ◽

Long Term Ventilation

Ventilation tube insertion plays an important role in the management of otitis media with effusion. In selected cases, repeated grommet insertion due to persistent eustachian tube dysfunction necessitates the need for longer-term ventilation. Insertion of such tubes can however occasionally be more difficult than insertion of standard grommets. One such long-term ventilation tube is the Shah permavent grommet. This paper describes a simple modification of the technique that is less time-consuming and less traumatic.

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Education of New Otolaryngologists Regarding Otitis Media with Effusion to Enhance Their Understanding of Eustachian Tube Dysfunction

Practica oto-rhino-laryngologica Suppl ◽

10.5631/jibirinsuppl.156.213 ◽

2021 ◽

Vol 156 (0) ◽

pp. 213-216

Author(s):

Aya Niwa ◽

Kunihiro Mizuta ◽

Shiori Endo ◽

Hiroshi Nakanishi ◽

Takashi Yamatodani ◽

...

Keyword(s):

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Tube Dysfunction

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Site of eustachian tube dysfunction in patients with otitis media with effusion

American Journal of Otolaryngology ◽

10.1016/s0196-0709(87)80021-2 ◽

1987 ◽

Vol 8 (6) ◽

pp. 361-363 ◽

Cited By ~ 16

Author(s):

Haruo Takahashi ◽

Akihiko Fujita ◽

Iwao Honjo

Keyword(s):

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Tube Dysfunction

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Otitis Media with Effusion and Eustachian Tube Dysfunction in Adults and Children

Acta Oto-Laryngologica ◽

10.3109/00016489309126183 ◽

1993 ◽

Vol 113 (sup500) ◽

pp. 66-69 ◽

Cited By ~ 17

Author(s):

Tadashi Iwano ◽

Takuya Kinoshita ◽

Eimoto Hamada ◽

Tadashi Doi ◽

Koichi Ushiro ◽

...

Keyword(s):

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Tube Dysfunction ◽

Adults And Children

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The Role of IgE-Mediated Hypersensitivity in Otitis Media with Effusion: A 1987 Update

American Journal of Rhinology ◽

10.2500/105065887781693349 ◽

1987 ◽

Vol 1 (2) ◽

pp. 67-72

Author(s):

Joel M. Bernstein

Keyword(s):

Allergic Rhinitis ◽

Otitis Media ◽

Eustachian Tube ◽

Otitis Media With Effusion ◽

Eustachian Tube Dysfunction ◽

Upper Respiratory Tract ◽

Direct Role ◽

Tube Dysfunction ◽

Ige Mediated

The role of IgE-mediated hypersensitivity in the development of middle ear disease has not been completely resolved. However, on the basis of our investigations and those of other laboratories, we would suggest that approximately two-thirds of patients with chronic recurrent otitis media (OM) are not allergic. The other third may have allergic rhinitis, and this allergic rhinitis may play a direct role in producing eustachian tube dysfunction in recurrent OM. However, viral infections of the upper respiratory tract may also induce IgE-mediated release of mast cell inflammatory mediators and could cause OM on the basis of viral infection alone. The role of allergic rhinitis on eustachian tube dysfunction is now well documented, and finally, the possible role of food allergy and OM must be seriously considered, particularly in the young OM-prone child with chronic recurrent rhinitis and OM.

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