33-LB: Nuclear Factor Erythroid 2 Related Factor 2 (Nrf2) Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 33-LB
Author(s):  
DHAMODHARAN UMAPATHY ◽  
POOJA VIKRAMAN ◽  
VAISHNAVI ALLADI ◽  
SOMASUNDAR ARUMUGAM ◽  
SIREESH DORNADULA ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcers ◽  
Related Factor ◽  
Nuclear Factor ◽  
Diabetic Foot Ulcers

scholarly journals IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Figen Aydin ◽  
Ahmet Kaya ◽  
Levent Karapinar ◽  
Mert Kumbaraci ◽  
Ahmet Imerci ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Significant Difference ◽  
The Mean ◽  
Design And Methods

Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ulcers.Design and Methods. We treated 48 consecutive patients with diabetic foot ulcers with HBOT. Alterations of IGF-1 levels in patients whose wound healed with HBOT were compared with those in patients who did not benefit from HBOT.Results. There was no significant difference in initial IGF-1 levels between the two groups(P=0.399). The mean IGF-1 level increased with HBOT(P<0.05). In the healed group, the mean IGF-1 increase and the final values were significantly higher(P<0.05). In the nonhealed group, the mean IGF-1 increase was minus and the final values were not significantly different(P<0.05). The increase in IGF-1 level with HBOT was significantly higher in the healed group(P<0.001).Conclusions. IGF-1 increased significantly in the healed group. We believe that HBOT is effective in the treatment of diabetic foot ulcers, with an elevation of IGF-1. This alteration seems to be a predictive factor for wound healing in diabetic foot ulcers treated with HBOT.

Evaluation of the role of hyperbaric oxygen therapy in the treatment of diabetic foot ulcers: a prospective comparative study

2016 ◽  
Vol 88 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Chandrakant Munjewar ◽  
Ishaq Nabi ◽  
Santosh Gautam ◽  
Neelam Ahirwar ◽  
Poras Chaudhary ◽  
...  
Keyword(s):  
Comparative Study ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Prospective Comparative Study

The need for differentiation between ischaemic and non‐ischaemic diabetic foot ulcers when treating with hyperbaric oxygen therapy

2019 ◽  
Vol 37 (2) ◽  
pp. 370-371
Author(s):  
R. J. Brouwer ◽  
R. C. Lalieu ◽  
R. Hoencamp ◽  
R. A. Hulst ◽  
D. T. Ubbink
Keyword(s):  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

scholarly journals Can major amputation rates be decreased in diabetic foot ulcers with hyperbaric oxygen therapy?

2008 ◽  
Vol 33 (2) ◽  
pp. 441-446 ◽  
Author(s):  
Ahmet Kaya ◽  
Figen Aydin ◽  
Taskin Altay ◽  
Levent Karapinar ◽  
Hasan Ozturk ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Major Amputation ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers
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