Two Cases of Primary Yolk Sac Tumor of the Liver in Childhood: Case Reports and Literature Review

2009 ◽  
Vol 12 (5) ◽  
pp. 410-416 ◽  
Author(s):  
Mikako Warren ◽  
Karen S. Thompson
Keyword(s):  
Liver Biopsy ◽  
Literature Review ◽  
Tumor Cells ◽  
Case Reports ◽  
Primary Source ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Recurrent Tumor ◽  
Normal Range ◽  
Characteristic Features

Primary yolk sac tumor of the liver is an extremely rare neoplasm, with fewer than 20 cases reported. We evaluated 2 pediatric cases (21-month-old and 23-month-old female patients), who presented with liver masses and markedly raised serum α-fetoprotein (AFP). One patient received a partial hepatectomy and another patient underwent a liver biopsy, both of which showed characteristic features of yolk sac tumor, with tumor cells staining strongly positive for AFP. There was no evidence of an extrahepatic primary source. Both of our patients have been healthy, without evidence of recurrent tumor, and their AFP level remains in the normal range after their chemotherapeutic treatments.

scholarly journals Role of Radiotherapy in Recurrent Intra-Abdominal Yolk Sac Tumor

2021 ◽  
pp. 1010-1018
Author(s):  
Marhendra Satria Utama ◽  
Andi Kurniadi ◽  
A.A. Citra Yunda Prahastiwi ◽  
Antony A. Adibrata
Keyword(s):  
Case Reports ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Appropriate Treatment ◽  
Curative Radiotherapy ◽  
Chief Complaints ◽  
Abdominal Mri ◽  
Malignant Germ Cell Tumor

Yolk sac tumor (YST) is a rare malignant germ cell tumor with no appropriate treatment strategy to date. However, patients are treated on a case-to-case basis as per various case reports that have been published. Here, we present a case of 27-year-old female patient who presented to us with chief complaints of severe abdominal pain associated with leucorrhea. She previously had a similar pain episode, which was then evaluated by a multidisciplinary team. She was diagnosed with YST. After that, she underwent 6 cycles of chemotherapy, but there was no improvement. Then the medical oncologist referred her to performed radiotherapy. Then, the radiation oncologist decided to give her curative radiotherapy of 3D-CRT. After completing her sessions, she felt better and clinically improving. After that, she was discharged and scheduled a follow-up visit for first evaluation. At her follow-up visit, she was feeling well, and we decided to have an abdominal MRI.

Sinonasal Pure Yolk Sac Tumor: A Case Report and Literature Review

2014 ◽  
Vol 33 (3) ◽  
pp. 127-134 ◽  
Author(s):  
Huei Chieh Chuang ◽  
Chung-Jan Kang ◽  
Li-yu Lee
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Yolk Sac ◽  
Yolk Sac Tumor

scholarly journals Difficulty in Diagnosing Peritoneal Fluid Cytology in Ovarian Yolk Sac Tumor Cases

2021 ◽  
Vol 5 (2) ◽  
pp. 276-284
Author(s):  
Haris Pemuda ◽  
Yenita Yenita ◽  
Pamelia Mayorita ◽  
Yessy Setiawati ◽  
Syamel Muhammad
Keyword(s):  
Ovarian Carcinoma ◽  
Microscopic Examination ◽  
Peritoneal Fluid ◽  
Tissue Sample ◽  
Case Reports ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Cytologic Examination ◽  
Microscopic Appearance ◽  
Optimal Debulking

Objective : This article objective is to describe cytology diagnosis difficulties of yolk sac tumors of the ovary.Method : Case reports and literature review.Case : The author reports the case of a 24 year old woman who complained of an enlarged stomach. Serum AFP increased to 16,519.7 U/mL. Ultrasound examination revealed solid and irregular mass of ovarian, so the conclusion was suspect ovarian carcinoma. Conclusion of CT scan examination was a solid ovarian tumor. The working diagnosis was suspect ovarian carcinoma. Optimal debulking was performed, accompanied by taking a sample from the peritoneal rinse fluid. Microscopic examination of peritoneal fluid showed the distribution and group of cells with pleomorphic nuclei, partly hyperchromatic, partly vesicular with coarse chromatin and prominent nucleoli. There were also cells with polygonal nuclei, small nuclei, basophilic and vacuole cytoplasm with a mucoid background. These cells formed a solid arrangement. Conclusion from these features was carcinoma metastases to the peritoneal fluid. Microscopic examination from tumor tissue sample showed an ovarian yolk sac tumor appearance.Conclusion : Cytologic examination of peritoneal fluid in cases of ovarian yolk sac tumor is quite difficult to determine the diagnosis. This is due to the microscopic appearance of tumor cells which often looks like a carcinoma and limited literature about this tumors in the peritoneal fluid.Keywords: Yolk sac tumor, ovary, 

scholarly journals MIXED GERM TUMOR WITH YOLK SAC TUMOR AND MATURE TERATOMA - CASE REPORT AND LITERATURE REVIEW

2019 ◽  
Author(s):  
Ketheryn Almeida ◽  
GUSTAVO CARVALHO ◽  
JOSE LUIS BRAVIN ◽  
Maria Inês Pereira da Silva Vianna ◽  
Vinicius Vicuna ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Mature Teratoma ◽  
Yolk Sac ◽  
Yolk Sac Tumor

Primary Yolk Sac Tumor of the Urachus

2002 ◽  
Vol 126 (9) ◽  
pp. 1106-1109 ◽  
Author(s):  
Hsuan-Ying Huang ◽  
Sheung-Fat Ko ◽  
Jiin-Haur Chuang ◽  
Yung-Ming Jeng ◽  
Ming-Tse Sung ◽  
...  
Keyword(s):  
Tumor Cells ◽  
P53 Protein ◽  
Germ Cell Tumors ◽  
Male Infant ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Resected Specimen ◽  
Abdominal Tumor ◽  
Yolk Sac Tumors ◽  
Urachal Adenocarcinoma

Abstract Pure yolk sac tumor is the most common malignant gonadal tumor of infants and toddlers. However, the majority of extragonadal germ cell tumors in the midline are either seminomas (germinomas) or teratomas, and pure yolk sac tumors account for only a small fraction of these lesions. To date, only 1 primary urachal pure yolk sac tumor has been reported in the literature. We describe another case, occurring in a 7-month-old male infant who presented with a rapidly enlarging intra-abdominal tumor with marked engorgement of the superficial venous plexus around the umbilicus. With periodic follow-up for 3 years following surgical extirpation of the tumor and adjuvant chemotherapy, this patient is still alive without evidence of disease. Notably, the glandular elements predominating in the frozen sections resulted in the initial misdiagnosis of the tumor as a urachal adenocarcinoma, although the entirely resected specimen revealed typical histologic patterns and Schiller-Duval bodies. Immunohistochemistry showed that the tumor cells were diffusely reactive to α-fetoprotein, α1-antitrypsin, and cytokeratin. Tumor cells were negative for p53 protein, but revealed overexpression for MDM2 protein. Flow cytometry demonstrated a diploid DNA content with S-phase being as high as 55.36%. This case emphasizes that pure yolk sac tumor can occur primarily in the remnant of the urachus in young children.

scholarly journals Primary yolk sac tumor of the gluteus: a case report and literature review

2016 ◽  
Vol Volume 9 ◽  
pp. 4715-4719
Author(s):  
Ling-Ou Yang ◽  
Qianqian Jiang ◽  
Shitai Zhang ◽  
Yang Zhou ◽  
qing-fu zhang ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Yolk Sac ◽  
Yolk Sac Tumor

scholarly journals Perioperative latex hypersensitivity reactions: an integrative literature review

2012 ◽  
Vol 20 (2) ◽  
pp. 411-420 ◽  
Author(s):  
Aline Nair Biaggio Mota ◽  
Ruth Natalia Teresa Turrini
Keyword(s):  
Literature Review ◽  
Case Reports ◽  
Primary Source ◽  
Allergic Reactions ◽  
Hypersensitivity Reactions ◽  
Anesthetic Induction ◽  
Prevalence Studies ◽  
Latex Gloves ◽  
Anesthetic Drugs ◽  
History Of

This article characterizes hypersensitivity reactions during anesthetic-surgical procedures. This integrative literature review was conducted in the LILACS, CINAHL, COCHRANE and MEDLINE databases including papers published from 1966 to September 2011. A total of 17 case reports, two prevalence studies and one cohort study were identified. Latex reactions were mainly type III and the primary source of intraoperative reaction was latex gloves. The average time for clinical manifestation was 59.8 minutes after anesthetic induction; 44.4% of patients reported a reaction to latex at the pre-anesthetic evaluation. It was determined that the history of allergic reactions to latex obtained in the pre-anesthetic evaluation does not ensure the safety of patients if the staff is inattentive to the severity of the issue. There is also a tendency to initially attribute the anaphylactic event to the anesthetic drugs.

scholarly journals 273 Mixed germ tumor with yolk SAC tumor and mature teratoma – case report and literature review

2019 ◽  
Author(s):  
K Almeida ◽  
G Carvalho G- Carvalho ◽  
JL Bravin JL- Bravin ◽  
MIPDS Vianna MIPS- Vianna ◽  
VHDS Vicuna VHS- Vicuna ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Mature Teratoma ◽  
Yolk Sac ◽  
Yolk Sac Tumor

Extragonadal endodermal sinus (Yolk Sac) tumor Angiographic findings and literature review

1978 ◽  
Vol 7 (2) ◽  
pp. 115-118 ◽  
Author(s):  
R. C. Brasch ◽  
A. A. de Lorimier ◽  
R. J. Herzog ◽  
F. C. Van Natta
Keyword(s):  
Literature Review ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Angiographic Findings

scholarly journals A Case Report of Yolk Sac Tumor in Cerebellar Hemisphere and Review of Literature

2020 ◽  
Author(s):  
Yuting Zhang ◽  
Lusheng Li ◽  
Ling He
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Case Reports ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Cerebellar Hemisphere ◽  
Review Of Literature ◽  
Intracranial Germ Cell Tumor ◽  
The Right

Abstract Background: Yolk sac tumor also known as endodermal sinus tumor, is a rare intracranial germ cell tumor. We reported a case of yolk sac tumor in cerebellar hemisphere, and reviewed associated literatures. The majority of tumor locations are near the midline. On review of literature, very few case reports of intracranial yolk sac tumor have been published, and there is only one case report has described a yolk sac tumor arising from the cerebellum. Case presentation: A two years old boy admitted to our hospital due to headache and unsteady gait for six days. CT and MRI demonstrated a tumor in the right cerebellar hemisphere, and the blood and cerebrospinal fluid alpha-fetoprotein were found increased. It was diagnosed as yolk sac tumor after operation comfirmed by histopathological examination. Postoperative chemotherapy was performed, and the patient suffered no tumor recurrence one year and a half after the surgery. Conclusions: The clinical characteristics and imaging diagnosis of intracranial yolk sac tumor are lack of specificity, the comfirmed diagnosis is depending on the combination of elevated alpha-fetoprotein and histopathological examination.

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