scholarly journals Inverted Papilloma against a Background of Bilateral Rhinosinusitis Polyposa with Viscous Mucin (Clinical Case)

2018 ◽  
Vol 8 (2) ◽  
pp. 70-74
Author(s):  
R. M. Pestova ◽  
E. E. Savel’eva ◽  
L. F. Aznabaeva ◽  
R. A. Sharipov

Introduction. Rhinosinusitis polyposa consists in a chronic inflammation of the mucous membrane of the nose and paranasal sinuses, followed by recurrent growth of polyps and characterised by a high prevalence. Nasal polyps may be associated with the presence of viscous mucin; their characteristic CT signs are hyperostosis of the walls of the affected sinuses and thinning cavity walls until the bone is destroyed, this being a sign of aseptic osteomyelitis. The same sign is typical for inverted papilloma, the most common benign tumour of the nose and sinuses.Materials and methods. The present article presents a clinical observation. What makes it interesting is that a benign tumour was diagnosed against the background of bilateral rhinosinusitis polyposa. The clinical picture did not have nasal bleeding, which is typical for inverted papilloma; this was most likely due to the initial growth of the tumour. Thickening bone structures (hyperostosis) was balanced due to the pathogenetic peculiarities of the rhinosinusitis polyposa development with viscous mucin. Inverted papilloma was suspected during rhinoscopy, which revealed asymmetric growth of polyps. Final verification of the clinical diagnosis was carried out following computerised tomography of the nose and paranasal sinuses and histological examination of biopsy material.Results and discussion. This clinical case is of interest due to rhinocytogram data suggesting a viral and inflammatory etiology of the development of inverted papilloma. Therefore, the observed nucleoli of the nuclei of the columnar epithelium are characteristic of intracellular infection — in particular, viral. Remodelling of cells of the cylindrical epithelium is a sign of chronic inflammatory process.Conclusion. Thus, accurate performance of the diagnostic algorithm with histological verification of all removed material allows the identification of a neoplasm of the nasal cavity even in difficult cases, along with other diseases of the nasal cavity. Rhinocytogram data can help suggest the etiology of the intracellular type of infection in the epithelial cell and pathogenesis of inverted papilloma in a particular case.

1991 ◽  
Vol 27 (2) ◽  
pp. 206
Author(s):  
Eun Young Kim ◽  
Dong Ik Kim ◽  
Jung Ho Suh ◽  
Tae Sub Chung

2021 ◽  
Vol 20 (1) ◽  
pp. 35-38
Author(s):  
Oleksandr Plaksyvyi ◽  
Ihor Kalutskyi ◽  
Olga Mazur

Inverted transitional cell papilloma (Schneider papilloma), a rare benign tumor, accounts for about 0.5% of all neoplasms of the nose. Usually unilateral, recurrences of the tumor can occur after 5-10 years. The clinical case testifi es to the gigantic size of the neoplasm, the germination of the inverted papilloma into the paranasal sinuses, the malignancy of the process and the metastasis of the tumor, which was not previously described. The main treatment for preventing recurrence is radical surgery, possibly with ligation of the external carotid artery.


1993 ◽  
Vol 72 (9) ◽  
pp. 588-595 ◽  
Author(s):  
Oreste Gallo ◽  
Paola Graziani ◽  
Omero Fini-Storchi

Among twenty-six “undifferentiated” tumors of the nasal cavity and paranasal sinuses treated from 1970 to 1990 at the Institute of Otolaryngology of Florence University, 13 were ultimately diagnosed as true undifferentiated sinusonasal carcinoma (SNUC) by conventional light microscopy and use of monoclonal antibodies to epithelial membrane antigen and cytokeratins. SNUC patients, who ranged in age from 20 to 82 years, often had multiple sinonasal symptoms due to very large tumors (nine of 13 tumors were staged as T3–T4) with short average delay of 4 months between onset of symptoms and diagnosis. Both data suggest the high growth capacity and aggressiveness of such a tumor. In our series, follow-up evidenced an overall crude 5-year survival rate of 15.5%. Worse prognostic factors are neck metastases and orbital invasion, according to the behavior of more common carcinomas of the nose and paranasal sinuses. We also found a better prognosis for SNUC primarily arisen in the nasal cavity than in paranasal sinuses (crude 5-year survival rate of 66% vs. 10%, respectively). The histopathological and clinical analysis of our series shows that SNUC is a highly aggressive, uncommon tumor of the nose paranasal sinuses, which should be recognized in advance for a more aggressive treatment by combined multiple therapy.


1999 ◽  
Vol 172 (2) ◽  
pp. 543-548 ◽  
Author(s):  
F Dammann ◽  
P Pereira ◽  
M Laniado ◽  
P Plinkert ◽  
H Löwenheim ◽  
...  

1988 ◽  
Vol 28 (4) ◽  
pp. 409-414
Author(s):  
Koichi UCHIDA ◽  
Tohru MINE ◽  
Nobuo TAKENAKA ◽  
Hiroshi INOUE ◽  
Hideo NAMEKI ◽  
...  

2012 ◽  
Vol 122 (3) ◽  
pp. 487-494 ◽  
Author(s):  
Dong-Young Kim ◽  
Sung-Lyong Hong ◽  
Chul Hee Lee ◽  
Hong-Ryul Jin ◽  
Jun Myung Kang ◽  
...  

2021 ◽  
Vol 29 (4) ◽  
pp. 202
Author(s):  
S.V. Movergoz ◽  
A.A. Andarov ◽  
D.I. Gorin ◽  
A.K. Gasnikova

1992 ◽  
Vol 71 (6) ◽  
pp. 264-266 ◽  
Author(s):  
Anthony J. D'Angelo ◽  
Andrew Marlowe ◽  
Frank I. Marlowe ◽  
Miles McFarland

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