scholarly journals Minimally invasive treatment of peristomal metastases from gastric cancer at an ileostomy site by electrochemotherapy

2013 ◽  
Vol 47 (4) ◽  
pp. 370-375 ◽  
Author(s):  
Luca G. Campana ◽  
Marco Scarpa ◽  
Antonio Sommariva ◽  
Elena Bonandini ◽  
Sara Valpione ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Minimally Invasive ◽  
Tumor Regression ◽  
Tumor Control ◽  
Invasive Treatment ◽  
Invasive Approach ◽  
Electric Pulses ◽  
Skin Conditions

Abstract Background. Peristomal metastases are rare, but potentially associated with relevant morbidity. Surgical resection, followed by stoma relocation, represent the gold standard in most patients. We describe electrochemotherapy (ECT), a minimally invasive method for locally-enhancing drug delivery by means of electric pulses, as an alternative approach. Patient and methods. A 49-year-old man with advanced gastric cancer developed skin metastases around an ileostomy site. The ulcerated and oozing tumor growth impaired patient’s quality of life due to continuous trouble in fitting the ostomy appliance, its poor adherence and consequent stools spillage. ECT consisted of a 20-minute course under mild general sedation. A bleomycin bolus of 15 000 IU/m2 was followed by the percutaneous application of multiple, 1.5 ms -long electric pulses by means of a needle electrode. Results. Post ECT course was uneventful and the patient was discharged on the same day. After one week, tumor nodules were flattened and partial tumor regression was appreciable at one-month follow-up. More importantly, peristomal skin conditions significantly improved, thus allowing for an effective application of the ostomy appliance during the following moths, until patient’s death. Conclusions. This report suggests the feasibility of ECT as a minimally invasive approach for peristomal tumors. In selected cases, ECT, by achieving a rapid tumor control, may ensure effective ostomy management and preserve patients’ quality of life.

scholarly journals Long Term Survival and Quality of Life after Minimally Invasive Surgery for Early Gastric Cancer.

1998 ◽  
Vol 31 (4) ◽  
pp. 1015-1019
Author(s):  
Tetsuro Kubota ◽  
Yoichiro Ishikawa ◽  
Soichiro Isshiki ◽  
Takeyoshi Yokoyama ◽  
Koji Fujita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Minimally Invasive Surgery ◽  
Early Gastric Cancer ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Term Survival ◽  
Long Term Survival

Minimally Invasive Separation Surgery for Metastases in the Vertebral Column: A Technical Report

2019 ◽  
Vol 18 (6) ◽  
pp. 606-613
Author(s):  
Rafael A Vega ◽  
Jeffrey I Traylor ◽  
Ahmed Habib ◽  
Laurence D Rhines ◽  
Claudio E Tatsui ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Minimally Invasive ◽  
Definitive Treatment ◽  
Invasive Technique ◽  
Thoracic Vertebrae ◽  
Minimally Invasive Techniques ◽  
Invasive Approach ◽  
Invasive Techniques

Abstract BACKGROUND Epidural spinal cord compression (ESCC) is a common and severe cause of morbidity in cancer patients. Minimally invasive surgical techniques may be utilized to preserve neurological function and permit the use of radiation to maximize local control. Minimally invasive techniques are associated with lower morbidity. OBJECTIVE To describe a novel, minimally invasive operative technique for the management of metastatic ESCC. METHODS A minimally invasive approach was used to cannulate the pedicles of the thoracic vertebrae, which were then held in place by Kirschner wires (K-wires). Following open decompression of the spinal cord, cannulated screws were placed percutaneously with stereotactic guidance through the pedicles followed by cement induction. Stereotactic radiosurgery is performed in the postoperative period for residual metastatic disease in the vertebral body. RESULTS The minimally invasive technique used in this case reduced tissue damage and optimized subsequent recovery without compromising the quality of decompression or the extent of metastatic tumor resection. Development of more minimally invasive techniques for the management of metastatic ESCC has the potential to facilitate healing and preserve quality of life in patients with systemic malignancy. CONCLUSION ESCC from vertebral metastases poses a challenge to treat in the context of minimizing potential risks to preserve quality of life. Percutaneous pedicle screw fixation with cement augmentation provides a minimally invasive alternative for definitive treatment of these patients.

scholarly journals Robot-assisted revision of sacroiliac joint fusion using a triangular titanium implant in an S2-alar-iliac trajectory: illustrative case

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Matthew Triano ◽  
Islam Fayed ◽  
Faheem A. Sandhu
Keyword(s):  
Quality Of Life ◽  
Minimally Invasive ◽  
Elderly Patients ◽  
Sacroiliac Joint ◽  
Titanium Implant ◽  
Invasive Technique ◽  
Illustrative Case ◽  
Robot Assisted ◽  
Invasive Approach

BACKGROUND Sacroiliac joint (SIJ) dysfunction can lead to significant pain and disability, greatly impairing quality of life. Arthrodesis may take up to 1 year to occur, after which revision can be considered. There is a need for highly accurate and reproducible techniques for revision that allow for purchase through undisturbed bone to prevent prolonged pain and disability. Moreover, a minimally invasive technique for revision would be favorable for recovery, particularly in elderly patients. OBSERVATIONS An 84-year-old man with a prior history of lumbar fusion presented with severe buttock pain limiting ambulation and sitting because of the failure of arthrodesis after SIJ fusion 1 year earlier. He underwent revision using a triangular titanium implant (TTI) in an S2-alar-iliac (S2-AI) trajectory under robotic guidance, which is a novel technique not yet described in the literature. The patient’s pain largely resolved, he was able to ambulate independently, and his quality of life improved tremendously. There were no complications of surgery. LESSONS Placement of a TTI using an S2-AI trajectory is a safe and effective method for revision that can be considered for elderly patients. Robot-assisted navigation can be used to facilitate an accurate and reproducible approach using a minimally invasive approach.

scholarly journals Palliative Electrochemotherapy Treatment of Cutaneous Metastases in a Patient with Advanced Thyroid Papillary Carcinoma

2020 ◽  
Vol 9 (4) ◽  
pp. 221-224
Author(s):  
Daniela Cavaco ◽  
Sara Carvalhal ◽  
Valeriano Leite
Keyword(s):  
Quality Of Life ◽  
Subcutaneous Tissue ◽  
Papillary Thyroid ◽  
Cytostatic Agents ◽  
Invasive Treatment ◽  
Cutaneous Metastases ◽  
Electric Pulses ◽  
Relieve Pain ◽  
Thyroid Papillary

Advanced papillary thyroid carcinoma (PTC) with cutaneous metastases may cause pain, ulceration, and bleeding. Electrochemotherapy (ECT) is a minimally invasive treatment of tumors located in the skin and subcutaneous tissue. The electric pulses potentiate the toxicity of cytostatic agents entering the tumor cell. It is highly effective especially to relieve pain and improve the quality of life. The adverse events are local and transient. A case of progressive metastatic PTC who developed bleeding cutaneous metastases treated with ECT is described.

Minimally Invasive Plication of the Diaphragm: A Single-Center Prospective Study

2021 ◽  
pp. 155698452110115
Author(s):  
Marco Nardini ◽  
Shruti Jayakumar ◽  
Marcello Migliore ◽  
Mario Nosotti ◽  
Ian Paul ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Minimally Invasive ◽  
Length Of Hospital Stay ◽  
Symptomatic Improvement ◽  
Postoperative Recovery ◽  
Safe Procedure ◽  
Invasive Approach ◽  
Telephone Consultation ◽  
Diaphragm Paralysis

Objective Plication of the diaphragm is a life-changing procedure for patients affected by diaphragm paralysis. Traditionally, this procedure is performed through a thoracotomy. Access to the diaphragm via this incision is poor and the indications for surgery are limited to patients who can actually sustain such an invasive approach and associated morbidities. A minimally invasive approach was developed to improve the surgical management of diaphragm paralysis. Methods Patients underwent minimally invasive diaphragm plication either by video-assisted or robotic surgery through a 3-port technique with CO2 insufflation. Patients were followed at the routine 6-week clinic and also by telephone consultation 6 to 12 months postoperatively. Data were collected on postoperative complications, postoperative pain or numbness, symptomatic improvement, and change to quality of life following surgery. Results Forty-eight patients underwent 49 minimally invasive diaphragm plication. Median postoperative length of hospital stay was 4 days (range: 2 to 34 days) and there were no cases of mortality. Mean reduction in Medical Research Council dyspnea score per patient was 2.2 points (mode: 3 points). Twenty-eight patients (77.8%) reported a significant symptomatic improvement enabling improvements in quality of life, and 97.2% ( n = 35) were satisfied with the surgical outcome. Conclusions Minimally invasive diaphragm plication is a safe procedure associated with prompt postoperative recovery. It is effective at reducing debilitating dyspnea and improving quality of life.

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