A new convenient synthesis of 5-aryl-2-(arylamino)-1,3,4-oxadiazole derivatives

2012 ◽  
Vol 66 (3) ◽  
Author(s):  
Sanjeev Kumar
Keyword(s):  
Platinum Electrode ◽  
Electrical Energy ◽  
Reaction Rates ◽  
Cell Assembly ◽  
Undivided Cell ◽  
Controlled Potential Electrolysis ◽  
Convenient Synthesis ◽  
Controlled Potential ◽  
Oxadiazole Derivatives

AbstractElectrical energy offers numerous benefits for conducting a synthesis, including increased reaction rates, yield enhancements and cleaner chemistries. 5-Aryl-2-(arylamino)-1,3,4-oxadiazoles were synthesised directly from acylthiosemicarbazide on the platinum electrode under controlled potential electrolysis in an undivided cell assembly in acetonitrile.

scholarly journals Synthesis of Some 2-Amino-5-substituted-1,3,4-oxadiazole Derivatives in the Acetic Acid

2011 ◽  
Vol 8 (s1) ◽  
pp. S448-S454 ◽  
Author(s):  
Sanjeev Kumar
Keyword(s):  
Acetic Acid ◽  
Room Temperature ◽  
Platinum Electrode ◽  
Supporting Electrolyte ◽  
Saturated Calomel Electrode ◽  
Reference Electrode ◽  
Lithium Perchlorate ◽  
Environmentally Benign ◽  
Controlled Potential ◽  
Oxadiazole Derivatives

An environmentally benign method for the preparation of 2-amino-5-substituted-1,3,4-oxadiazoles (1a-n) at platinum electrode through the electrooxidation of semicarbazone at room temperature is reported. The electrolysis were carried out at controlled potential in acetic acid solvent using lithium perchlorate as supporting electrolyte in an undivided cell assembly. Square shaped plates of platinum were used for working as well as counter electrode and a third electrode saturated calomel electrode was used as a reference electrode for the measurement of potential difference between two electrodes during the electrolysis.

Polarographic Behaviour of Some Arylazotheophyllines

1993 ◽  
Vol 58 (9) ◽  
pp. 1978-1988
Author(s):  
Mohamed I. Ismail ◽  
Madlene L. Iskander
Keyword(s):  
Diffusion Coefficient ◽  
Model Compound ◽  
Aqueous Media ◽  
Chemical Characteristics ◽  
Polarographic Behaviour ◽  
Physico Chemical ◽  
Controlled Potential Electrolysis ◽  
Azo Group ◽  
Controlled Potential ◽  
Electrolysis Products

The polarographic behaviour of a series of arylazotheophyllines was studied in aqueous alcoholic buffer media and in DMF-0.1 M LiClO4 solution. The redox study gave evidence that the azo group is electroactive in aqueous as well as non-aqueous media. A mechanism interpreting the electrode process is proposed and confirmed through the identification of the controlled potential electrolysis products, the use of a model compound and the application of Hamett's σ-E relationship. The physico-chemical characteristics of these compounds, viz. the diffusion coefficient, dissociation constant, ionization potential and electron affinity, are also included.

scholarly journals Electrochemical Behaviour of N′-(p-toluenesulphonyl)-3-methyl-4-(4′-substituted arylhydrazono) pyrazolin-5-ones

2012 ◽  
Vol 9 (4) ◽  
pp. 1864-1874
Author(s):  
V. Nagaraju ◽  
R. Sreenivasulu ◽  
P. Venkata Ramana
Keyword(s):  
Electrochemical Behaviour ◽  
Reduction Process ◽  
Effect Of Solvent ◽  
Buffer Solutions ◽  
Diffusion Controlled ◽  
Controlled Potential Electrolysis ◽  
Dc Polarography ◽  
Controlled Potential ◽  
Ph Range ◽  
And Diffusion

The electrochemical behaviour of N′-(p-toluenesulphonyl)-3-methyl-4-(4′-substituted arylhydrazono) pyrazolin-5-ones has been investigated at dme and gc electrodes in buffer solutions of pH 2.0, 4.0, 6.0, 8.0 and 10.0 using dc polarography and cyclic voltammetry and coulometry. The compounds exhibit one well defined wave in the entire pH range of study. The process is irreversible and diffusion controlled. Controlled potential electrolysis indicates the involvement of four electrons in the reduction process. The effect of solvent, cations and anions, temperature and substitutents on the mechanism of reduction has been studied. Based on the results obtained the mechanism of reduction has been suggested.

Substituent effects on polarographic reduction of some photographic color intermediates

1976 ◽  
Vol 54 (8) ◽  
pp. 1205-1210 ◽  
Author(s):  
Ahmad S. Shawali ◽  
Bahgat E. El-Anadouli
Keyword(s):  
Dissociation Constants ◽  
Substituent Effects ◽  
Protonated Form ◽  
Acid Dissociation ◽  
Polarographic Reduction ◽  
Substituent Constant ◽  
Acid Dissociation Constants ◽  
Controlled Potential Electrolysis ◽  
Half Wave ◽  
Controlled Potential

Polarographic reduction of two series of benzoylacetanilides has been investigated in 40% (by volume) ethanolic Britton–Robinson buffers. One series (A) contains substituents on the anilide moiety, and the second (B) has substituents on both the anilide and benzoyl moieties. Polarographic controlled-potential electrolysis data indicate that the electroactive species in both series is the protonated form (ArCOCH2CONHAr′)H+. The reduction half-wave potentials of anilides of series A were found to be independent of the nature of the substituent, whereas those of series B show a good linear relationship when plotted vs. the σ substituent constant of the substituent on the benzoyl moiety (ρ = 0.284, r = 0.995). Values of the acid dissociation constants of the keto (K1) and enol (K2) tautomers of the anilides of series A were calculated; unlike their E1/2 values, the pK1 data show a linear correlation with the Hammett substituent constant, σ. The pK2 values show, however, little variation with σ.

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