Enhanced chondrogenic differentiation of dental pulp-derived mesenchymal stem cells in 3D pellet culture system: effect of mimicking hypoxia

Biologia ◽  
2018 ◽  
Vol 73 (7) ◽  
pp. 715-726
Author(s):  
Sahar Khajeh ◽  
Vahid Razban ◽  
Tahereh Talaei-Khozani ◽  
Masoud Soleimani ◽  
Reza Asadi-Golshan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Dental Pulp ◽  
Culture System ◽  
Chondrogenic Differentiation ◽  
Pellet Culture ◽  
System Effect

scholarly journals The effect of synthesized cartilage tissue from human adipose-derived mesenchymal stem cells in orthopedic spine surgery in patients with osteoarthritis

2021 ◽  
Vol 67 (3) ◽  
pp. 133-137
Author(s):  
Tang Weijie ◽  
Guan Xinhua ◽  
Han Jingqi ◽  
Yin XiLing ◽  
Feng Zuoji
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Spine Surgery ◽  
Culture System ◽  
Joint Disease ◽  
Cartilage Tissue ◽  
Pellet Culture ◽  
Spinal Osteoarthritis ◽  
One Year ◽  
Over Time

Osteoarthritis is a joint disease that causes degeneration of articular cartilage and involvement of subcutaneous bone and inflammation of surrounding tissues. It can affect any joints, but the most common joints are the joints of the hands, feet, knees, thighs, and spine. Osteoarthritis patients need surgery in acute cases. The use of methods that increase the efficiency of this surgery has always been considered by researchers and surgeons. For this purpose, in the current study, the effect of synthesized cartilage tissue from human adipose-derived mesenchymal stem cells was considered in orthopedic spine surgery in patients with osteoarthritis. Thirty patients over the age of 60 who had acute spinal osteoarthritis and required surgery were selected. The pellet culture system of human adipose-derive mesenchymal stem cells of each patient was used to construct cartilage tissue. For 15 of them, in addition to implants, cartilage grafts were transplanted during surgery. All patients were monitored by the Oswestry Disability Index questionnaire, for one year. In general, the results showed that over time, patients with transplanted cartilage tissue and implants were in a better condition than patients who underwent only implant surgery.

Cartilaginous ECM component-modification of the micro-bead culture system for chondrogenic differentiation of mesenchymal stem cells

Biomaterials ◽  
2007 ◽  
Vol 28 (28) ◽  
pp. 4056-4067 ◽  
Author(s):  
Ying-Nan Wu ◽  
Zheng Yang ◽  
James H.P. Hui ◽  
Hong-Wei Ouyang ◽  
Eng Hin Lee
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Culture System ◽  
Chondrogenic Differentiation

Chondrogenic differentiation of human mesenchymal stem cells: a comparison between micromass and pellet culture systems

2010 ◽  
Vol 32 (9) ◽  
pp. 1339-1346 ◽  
Author(s):  
Liangming Zhang ◽  
Peiqiang Su ◽  
Caixia Xu ◽  
Junlin Yang ◽  
Weihua Yu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Chondrogenic Differentiation ◽  
Human Mesenchymal Stem Cells ◽  
Pellet Culture ◽  
Culture Systems
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