scholarly journals Diagnostic value of electrocardiogram stress testing in patients with metabolic syndrome

2015 ◽  
Vol 21 (1) ◽  
pp. 9-15
Author(s):  
Jolita Badarienė ◽  
Jelena Čelutkienė ◽  
Dovilė Petrikonytė ◽  
Jūratė Balsytė ◽  
Egidija Rinkūnienė ◽  
...  

SummaryObjectives:The aim of this study was to assess the diagnostic value of exercise stress testing to detect coronary heart disease (CHD) in the group of patients with metabolic syndrome.Design and methods: 2803 patients without prior diagnosis of CHD and identified metabolic syndrome were investigated. Subjects underwent electrocardiogram (ECG) stress testing and, depending on the results, coronary angiography and/or coronary computed tomography angiography to detect hemodynamically significant stenosis. CHD was confirmed, if lumen narrowing ≥ 50% of coronary arteries was found.Results: Exercise stress testing was interpreted as positive in 12% patients (71.7% women and 28.3% men). CHD was diagnosed in 45 patients (1.6%), 23 of them had positive exercise stress testing. ECG stress testing was more frequently positive in patients, who had typical/atypical anginal chest pain, dyspnea and/or non-anginal chest pain, in comparison to asymptomatic patients (16.6% vs 8.9%, p <0.001). CHD was more often diagnosed in symptomatic patients compared to patients with no symptoms (6.1% vs 0.7%, p < 0.001, women 5.3% vs 0.6%, p < 0.001, men respectively 8% vs 0.8%, p < 0.001).Conclusions: Diagnostic value of exercise stress testing for detecting CHD is limited in population with metabolic syndrome. CHD was more prevalent in patients with chest pain or dyspnea than in asymptomatic patients.

2015 ◽  
Vol 24 (9) ◽  
pp. 879-884 ◽  
Author(s):  
Jaimi H. Greenslade ◽  
William Parsonage ◽  
Ariel Ho ◽  
Adam Scott ◽  
Emily Dalton ◽  
...  

1975 ◽  
Vol 1 (3) ◽  
pp. 251-259 ◽  
Author(s):  
Robert R. Goodin ◽  
Jerry M. Graham ◽  
James S. Gwinn ◽  
Ronald R. Masden ◽  
Daniel E. McMartin ◽  
...  

2009 ◽  
Vol 27 (7) ◽  
pp. 889-892 ◽  
Author(s):  
Asia Kogan ◽  
Reuma Shapira ◽  
Basil S. Lewis ◽  
Ada Tamir ◽  
Gad Rennert

2003 ◽  
Vol 96 (11) ◽  
pp. 1121-1127 ◽  
Author(s):  
Steven J. Weiss ◽  
Amy A. Ernst ◽  
Gary Godorov ◽  
Deborah B. Diercks ◽  
Josh Jergenson ◽  
...  

2017 ◽  
Vol 238 ◽  
pp. 166-172 ◽  
Author(s):  
Christian Puelacher ◽  
Max Wagener ◽  
Roger Abächerli ◽  
Ursina Honegger ◽  
Nundsin Lhasam ◽  
...  

2011 ◽  
Vol 29 (4) ◽  
pp. 427-431 ◽  
Author(s):  
Brittany A. Zwischenberger ◽  
Billy J. Moore ◽  
Samuel D. Luber ◽  
Florence J. Dallo

CJEM ◽  
2007 ◽  
Vol 9 (06) ◽  
pp. 435-440 ◽  
Author(s):  
Doug Richards ◽  
Nazanin Meshkat ◽  
Jaqueline Chu ◽  
Kevin Eva ◽  
Andrew Worster

ABSTRACTIntroduction:Numerous patients are assessed in the emergency department (ED) for chest pain suggestive of acute coronary syndrome (ACS) and subsequently discharged if found to be at low risk. Exercise stress testing is frequently advised as a follow-up investigation for low-risk patients; however, compliance with such recommendations is poorly understood. We sought to determine if compliance with follow-up for exercise stress testing is higher in patients for whom the investigation is ordered at the time of ED discharge, compared with patients who are advised to arrange testing through their family physician (FP).Methods:Low-risk chest pain patients being discharged from the ED for outpatient exercise stress test and FP follow-up were randomized into 2 groups. ED staff ordered an exercise stress test for the intervention group, and the control group was advised to contact their FP to arrange testing. The primary outcome was completion of an exercise stress test at 30 days, confirmed through both patient contact and stress test results. Patients were unaware that our primary interest was their compliance with the exercise stress testing recommendations.Results:Two-hundred and thirty-one patients were enrolled and baseline characteristics were similar between the 2 groups. Completion of an exercise stress test at 30 days occurred in 87 out of 120 (72.5%) patients in the intervention group and 60 out of 107 (56.1%) patients in the control group. The difference in compliance rates (16.4%) between the 2 groups was statistically significant (χ2= 6.69,p&lt; 0.001) with a relative risk of 1.29 (95% confidence interval 1.18–1.40), and the results remained significant after a “worst case” sensitivity analysis involving 4 control group cases lost to follow-up. When subjects were contacted by telephone 30 days after the ED visit, 60% of those who were noncompliant patients felt they did not have a heart problem and that further testing was unnecessary.Conclusion:When ED staff order an outpatient exercise stress test following investigation for potential ACS, patients are more likely to complete the test if it is booked for them before ED discharge. After discharge, many low-risk chest pain patients feel they are not at risk and do not return to their FP for further testing in a timely manner as advised. Changing to a strategy of ED booking of exercise stress testing may help earlier identification of patients with coronary heart disease.


2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Dana Pop ◽  
Alexandra Dădârlat ◽  
Gyorgy Bodizs ◽  
Liana Stanca ◽  
Dumitru Zdrenghea

Aim. To assess the plasma leptin responses after exercise stress testing in patients with metabolic syndrome (MS). Material and Methods. We investigated 67 patients with MS, with mean age of 55±7 years. They underwent exercise stress testing on cycloergometer. The lot was divided into three groups: group 1—10 patients with a true positive test, group 2—18 patients with a true negative test, and group 3—39 patients with a false negative test. Leptin levels were measured using the ELISA method. Results. Leptin levels decreased after effort in patients with MS (9.42±11.08 ng/mL before and 8.18±11.5 ng/mL after the exercise stress test, P=0.0005, r=0.874). In groups 1 (8.98±9.09 at rest versus 5.98±8.73 ng/mL after the exercise test, P=0.002) and 3 (8.6±10.53 at rest versus 6.91 ± 9.07 ng/mL, P=0.0005), lower leptin levels were recorded immediately after exercise testing. Leptin levels were not significantly lower in group 2 before effort (9.49±11.36 ng/ml) and after (9.46±13.81 ng/mL). We found no correlation between leptinemia and exercise stress testing parameters, regardless of group. Conclusion. Our research showed that short-term exercise lowers leptin levels in coronary patients, without a relationship between its parameters and leptin values.


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