scholarly journals Biochemical Endothelial Injury and Platelets Activation Detectionin Endovenous Laser Ablation of Varicose Veins

2021 ◽  
Vol 6 (1) ◽  
pp. 1-5
Author(s):  
Ayman M Fakhry ◽  

Background: Thrombus formation and extension to femoral or popliteal veins and pulmonary embolism may be though as a complication of EVLT in varicose veins treatment we aimed to study the thermal energy effect of the procedure under standardized conditions on biochemical markers of platelets and endothelium activities. Patients and methods: 25 patients admitted to vascular surgery dept. of Alexandria armed forces hospital with varicose veins and GSV. reflux and all treated by endovenous laser ablation during: 1/1/2018_12/31/2018. Venous blood samples were taken from iliofemoral and antecubital veins, before during and one day after surgery of P-selectin, soluble thrombomodulin, fibrin degradation products and D-dime Results: There was no immediate rise of P-selectin and s TM in neither iliofemoral nor antecubital veins, where FDPs D-dimer was significantly elevated post operatively in the two regions. Conclusion: 1480 pulsed mode diode laser doesn’t induce measurable endothelial and platelets activation in iliofemoral region during endovenous ablation of varicose veins.

2010 ◽  
Vol 51 (6) ◽  
pp. 1474-1478 ◽  
Author(s):  
Thomas Schwarz ◽  
Eva von Hodenberg ◽  
Christian Furtwängler ◽  
Aljoscha Rastan ◽  
Thomas Zeller ◽  
...  

2011 ◽  
Vol 98 (4) ◽  
pp. 501-510 ◽  
Author(s):  
D. Carradice ◽  
A. I. Mekako ◽  
F. A. K. Mazari ◽  
N. Samuel ◽  
J. Hatfield ◽  
...  

2009 ◽  
Vol 24 (2) ◽  
pp. 247-251 ◽  
Author(s):  
Renate R. van den Bos ◽  
Michael A. Kockaert ◽  
H. A. Martino Neumann ◽  
Rolf H. Bremmer ◽  
Tamar Nijsten ◽  
...  

2015 ◽  
Vol 31 (4) ◽  
pp. 296-298 ◽  
Author(s):  
Luca Spinedi ◽  
Daniel Staub ◽  
Heiko Uthoff

Stroke is a very rare but potential fatal complication of endovenous thermal treatment in patients with a right-to-left shunt. To our best knowledge, there are only two reports in the literature of stroke after endovenous thermal ablation of varicose veins, one after endovenous laser ablation and one after radiofrequency ablation and phlebectomy, both treated conservatively. This report describes a successful lysis in a patient with an ischemic stroke associated with bilateral endovenous heat-induced thrombosis class I after endovenous laser ablation of both great saphenous vein and extensive miniphlebectomy in a patient with an unknown patent foramen ovale.


2007 ◽  
Vol 33 (10) ◽  
pp. 1243-1249 ◽  
Author(s):  
SANG WOO PARK ◽  
IK JIN YUN ◽  
JAE JOON HWANG ◽  
SONG AM LEE ◽  
JUN SEOK KIM ◽  
...  

Author(s):  
Claudio Castagno ◽  
Gianfranco Varetto ◽  
Caterina Guiot ◽  
Matteo Destro ◽  
Luigi Contessa ◽  
...  

2012 ◽  
Vol 28 (5) ◽  
pp. 248-256 ◽  
Author(s):  
N Samuel ◽  
T Wallace ◽  
D Carradice ◽  
G Smith ◽  
F Mazari ◽  
...  

Objective: We aimed to assess the evolution of an endovenous laser ablation (EVLA) practice in the management of varicose veins in a university teaching hospital vascular surgical unit, over five years. Methods: This was a retrospective review of a prospectively collected database of patients undergoing EVLA for great saphenous vein incompetence and followed up for a year. For inter- and intragroup comparison, patients were divided into three groups: group A: endovenous access generally established at the perigenicular level ( n = 105); group B: when practice changed to gain access at lowest point of demonstrable reflux ( n = 70); and group C: when tumescence delivery changed from manual injections to delivery via peristaltic pump ( n = 49). Outcomes including pain scores, time taken to return to normal functioning, quality of life (QoL), venous clinical severity scores (VCSS) and complication rates were evaluated. Results: Intergroup analysis: increase in the length of vein treated and laser density delivered was observed over time, even as median procedure duration decreased ( P < 0.001). An increase in sensory disturbance was noticed in group C ( P = 0.047) while better Aberdeen Varicose Vein Questionnaire (AVVQ) ( P = 0.004), SF-36® physical domains ( P < 0.05) and patient satisfaction with treatment ( P = 0.025) were recorded in the same group at 52 weeks. No significant difference was observed in technical failure, pain scores, return to normal functioning, VCSS and recurrence rates post-intervention. Intragroup analysis: QoL measures (AVVQ, SF-36®, EQ-5D) and VCSS scores demonstrated significant improvement at 12 and 52 weeks compared with baseline ( P < 0.05). Conclusions: Increase in length of vein treated and energy delivery seems to improve short-term outcomes; however, operators need to be wary of a possible concurrent increase in paraesthetic complications.


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