scholarly journals A Model to Study the Inhibition of Arginase II with Noscapine & Its Derivatives

2020 ◽  
Vol 2 (2) ◽  
pp. 1-14
Author(s):  
Prashant Singh ◽  

Background and Purpose Nitrate tolerance can be explained based on the reduction of the vessel responsiveness and the same is used for endogenous vasodilator Nitric Oxide (NO). There are some limitations for the treatment of ischaemia, angina etc. and it attracted the scientists and researchers. The location of arginase II is endothelial cells in mitochondria and it is used to change the potency of endothelial nitric oxide synthase.

Circulation ◽  
2009 ◽  
Vol 119 (6) ◽  
pp. 871-879 ◽  
Author(s):  
Cleide Gonçalves da Silva ◽  
Anke Specht ◽  
Barbara Wegiel ◽  
Christiane Ferran ◽  
Elzbieta Kaczmarek

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