Ciclesonide improves health-related quality of life in adults and adolescents with mild-to-moderate persistent asthma

2008 ◽  
Vol 29 (5) ◽  
pp. 521-527 ◽  
Author(s):  
Robert A. Nathan ◽  
Lewis Kanter ◽  
Nancy K. Ostrom
2010 ◽  
Vol 35 (10) ◽  
pp. 1133-1143 ◽  
Author(s):  
Michael Seid ◽  
James W. Varni ◽  
Pradeep Gidwani ◽  
Leticia Reyes Gelhard ◽  
Donald J. Slymen

Abstract Objectives To test the efficacy of problem-solving skill training (PST) in improving health-related quality of life (HRQOL) of children with persistent asthma from predominantly lower socioeconomic status (SES) Spanish-speaking Hispanic families. Methods Randomized controlled trial comparing standard care waitlist (SC) control, home-visiting asthma education/care coordination (CC), and combined intervention (CC + PST) at baseline, after intervention, and 6-month follow-up. The primary outcome was parent proxy-report child HRQOL (PedsQL). Results Participants (n = 252) were 83.3% Hispanic and 56.3% monolingual Spanish speakers, and 72.6% of mothers had not graduated high school. We found a significant (P = 0.05) intervention effect for parent proxy-reported child generic (but not asthma-specific) HRQOL, with CC + PST superior to SC [83.8 vs 79.8; adjusted mean difference of 4.05 points (95% confidence interval 0.63–7.4], but no difference between the CC and SC groups. Conclusions In this sample of vulnerable families of children with persistent asthma, a CC + PST intervention was efficacious in improving children’s generic HRQOL.


2004 ◽  
Vol 98 (12) ◽  
pp. 1157-1165 ◽  
Author(s):  
Jacqueline R. Carranza Rosenzweig ◽  
Lisa Edwards ◽  
William Lincourt ◽  
Paul Dorinsky ◽  
Richard L. ZuWallack

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