Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy

2011 ◽  
Vol 32 (2) ◽  
pp. 142-150 ◽  
Author(s):  
Petr Panzner ◽  
Mark Petráš ◽  
Tomáš Sýkora ◽  
Ivana Králová Lesná ◽  
Martin Liška
Keyword(s):  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy ◽  
Routes Of Administration

Immunotheraphy in Allergic Diseases

2018 ◽  
Vol 24 (11) ◽  
pp. 1174-1194
Author(s):  
Albert Roger ◽  
Maria Basagana ◽  
Aina Teniente-Serra ◽  
Nathalie Depreux ◽  
Yanina Jurgens ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
World Population ◽  
Allergen Specific Immunotherapy ◽  
Routes Of Administration ◽  
Disease Modifying Therapy ◽  
History Of ◽  
Ige Mediated ◽  
Special Case

The prevalence of allergic diseases is increasing worldwide. It is estimated that more than 30% of the world population is now affected by one or more allergic conditions and a high proportion of this increase is in young people. The diagnosis of allergy is dependent on a history of symptoms on exposure to an allergen together with the detection of allergen-specific IgE. Accurate diagnosis of allergies opens up therapeutic options. Allergen specific immunotherapy is the only successful disease-modifying therapy for IgE-mediated allergic diseases. New therapeutic strategies have been developed or are currently under clinical trials. Besides new routes of administration, new types of allergens are being developed. The use of adjuvants may amplify the immune response towards tolerance to the antigens. In this review, we analyze different antigen-specific immunotherapies according to administration route, type of antigens and adjuvants, and we address the special case of food allergy.

Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis

2017 ◽  
Vol 131 (11) ◽  
pp. 997-1001 ◽  
Author(s):  
E Sahin ◽  
D Dizdar ◽  
M E Dinc ◽  
A A Cirik
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Specific Immunotherapy ◽  
Subcutaneous Immunotherapy ◽  
Long Term Effects ◽  
Allergen Specific Immunotherapy ◽  
Dust Mite ◽  
Symptom Scores

AbstractBackground:Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.Methods:The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).Results:The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p < 0.0175). There were no significant differences between the scores obtained at 3 years and 10 years after allergen-specific immunotherapy (p > 0.0175).Conclusion:Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.

Long-term Allergen-specific Immunotherapy Results in Allergic Rhinitis

2010 ◽  
Vol 129 ◽  
pp. 64-67 ◽  
Author(s):  
Kohei Honda ◽  
Chikara Asaka ◽  
Naoko Fukui ◽  
Eiko Ito ◽  
Kazuo Ishikawa
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

scholarly journals Late Local Urticaria as a Long-term Sequela of Allergen-Specific Immunotherapy

2004 ◽  
Vol 19 (3) ◽  
pp. 202-204 ◽  
Author(s):  
In Seon S. Choi ◽  
Young Il I. Koh ◽  
Se Woong Chung ◽  
Jeong Ook Wi ◽  
Doo Seon Sim
Keyword(s):  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

scholarly journals Long-term Efficacy of Allergen-specific Immunotherapy for Perennial Allergic Rhinitis

1999 ◽  
Vol 1999 (Supplement102) ◽  
pp. 44-49
Author(s):  
Keiko Okano ◽  
Sachio Takeno ◽  
Takaharu Matsushima ◽  
Sitau Hirata ◽  
Koji Yajin ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Perennial Allergic Rhinitis ◽  
Allergen Specific Immunotherapy ◽  
Term Efficacy

Management of canine atopic dermatitis

2020 ◽  
Vol 25 (6) ◽  
pp. 162-167
Author(s):  
Hannah Lipscomb ◽  
Filippo De Bellis
Keyword(s):  
Atopic Dermatitis ◽  
Specific Immunotherapy ◽  
Clinical Signs ◽  
Term Treatment ◽  
Allergen Specific Immunotherapy ◽  
Canine Atopic Dermatitis ◽  
Long Term Treatment ◽  
Fast Acting ◽  
Oral Glucocorticoids

Canine atopic dermatitis can present in two different ways — acute versus chronic — which require different treatment. When dealing with an acute flare, it is important to try and identify and eliminate the trigger and then provide fast-acting topical and/or systemic treatment. The treatment of chronic atopic dermatitis differs as it includes identification of flare factors, treatment of pruritus and prevention strategies. For long-term treatment of pruritus, there are currently four licenced prescription options available: oral glucocorticoids, oral ciclosporin, oral oclacitinib and injectable lokivetmab. The key prevention strategy for canine atopic dermatitis is allergen-specific immunotherapy and it is currently the only treatment that may induce complete remission of clinical signs. Alongside treatment for cases of canine atopic dermatitis, it is important to effectively communicate with clients in order to achieve compliance and medical adherence.

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