scholarly journals Predicting coronary graft occlusion in males with type 2 diabetes: an annual prospective study

2020 ◽  
Vol 27 (4) ◽  
pp. 189-200
Author(s):  
N. S. Lisytenko ◽  
N. A. Morova ◽  
V. N. Tsekhanovich
Keyword(s):  
Type 2 Diabetes ◽  
Left Ventricle ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Coronary Bypass ◽  
Bypass Grafting ◽  
Graft Occlusion ◽  
Bypass Patency ◽  
One Year

Aim. Identification of factors affecting coronary bypass graft patency in patients with type 2 diabetes (T2D) during one year after coronary bypass grafting.Materials and methods. Coronary artery bypass grafting for stable effort angina was ordered in 23 men with T2D. The patients had transthoracic echocardiogram before surgery. All patients were verified for lupus anticoagulant (LA) in blood on the 14th day after surgery. A year later, the patients underwent coronary shuntography to assess bypass patency.Results. LA was detected in 15 of 23 patients (65%). One year after surgery, occlusions of coronary shunts were revealed in 10 of 23 patients. In patients with coronary shunt occlusions, end-diastolic and end-systolic dimensions, end-diastolic and end-systolic volumes, end-systolic and end-diastolic indices (EDD, ESD, EDV, ESV, ESI, EDI, respectively), as well as the LA ratio significantly exceeded those in patients without occlusions (Mann—Whitney p values 0.004, 0.012, 0.012, 0.006, 0.006, 0.004, 0.017, respectively). A method is proposed for predicting coronary shunt occlusions based on assessment of end-diastolic volume of left ventricle and the LA ratio.Conclusion. Echocardiographic values for left ventricle (EDD, ESD, EDV, ESV, ESI, EDI) and the LA ratio are predictors of coronary graft occlusions in patients with type 2 diabetes.

scholarly journals A Novel Risk Scoring Tool to Predict Saphenous Vein Graft Occlusion in Patients with Type 2 Diabetes Mellitus After Cardiac Artery Bypass Graft Surgery

2020 ◽  
Author(s):  
Yujing Cheng ◽  
Xiaoteng Ma ◽  
Xiaoli Liu ◽  
Yingxin Zhao ◽  
Yan Sun ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Validation Cohort ◽  
Saphenous Vein Graft ◽  
Artery Bypass ◽  
Graft Occlusion ◽  
Risk Scoring ◽  
Predictive Risk ◽  
Scoring Tool

Abstract Background: Coronary artery bypass grafting (CABG) success is reduced by graft occlusion. Patients with type 2 diabetes mellitus(T2DM) are more likely to develop graft occlusion. Understanding factors associated with graft occlusion may improve T2DM patient outcomes. The aim of this study was to develop a predictive risk score for saphenous vein graft (SVG) occlusion in T2DM patients after CABG.Methods: This retrospective cohort study enrolled 3716 CABG patients with T2DM from January 2012 to March 2013. The development cohort included 2477 patients and the validation cohort included 1239 patients. The baseline clinical data at index CABG was analyzed for their independent impact on graft occlusion in our study using Cox proportional hazards regression. The predictive risk scoring tool was weighted by beta coefficients from the final model. Concordance (c)-statistics and comparison of the predicted and observed probabilities of predicted risk were used for discrimination and calibration.Results: A total of 959 (25.8%) out of 3716 patients developed at least one SVG occlusion. Significant risk factors for occlusion were male sex, estimated glomerular filtration rate<90, smoking (currently), hyperuricemia, dyslipidemia, prior percutaneous coronary intervention (PCI), a rising number of lesion vessels, and SVG. On-pump surgery, and the use of angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) and calcium channel blockers (CCB) were protective factors. The risk scoring tool with 11 variables was developed from the derivation cohort, which delineated each patient into risk quartiles. The c-statistic for this model was 0.71 in the validation cohort.Conclusions: An easy-to-use risk scoring tool that used common clinical variables was developed and validated. The scoring tool accurately estimated the risk of late SVG occlusion in T2DM patients after CABG.

scholarly journals Neuropsychological dynamics in patients with type 2 diabetes mellitus undergone coronary artery bypass grafting

2012 ◽  
Vol 15 (4) ◽  
pp. 33-38 ◽  
Author(s):  
Olga Alexandrovna Trubnikova ◽  
Anastasia Sergeevna Mamontova ◽  
Irina Danilovna Syrova ◽  
Olga Valer'evna Maleva ◽  
Olga Leonidovna Barbarash
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Diabetic Patients ◽  
Bypass Grafting

AIM: The study was aimed at evaluation of hospital neuropsychological dynamics in ischemic heart disease patients with comorbid type 2 diabetes mellitus (T2DM) undergone on-pump coronary artery bypass grafting. MATERIALS AND METHODS: 14 from a total of 37 examined patients had T2DM. Diabetic patients were found to have lower attention parameters prior to the intervention in comparison to non-diabetic controls. At days 7-10 after the surgery all patients demonstrated deterioration of cognitive functions. RESULTS: We observed deeper deterioration in diabetic patients, regarding attention, memory, sensorimotor speed and quantity of erroneous test responses, as measured against individuals with normal glucose tolerance. CONCLUSIONS: Diabetic patients undergone coronary artery bypass surgery show lower cognitive characteristics when compared to controls without T2DM, suggesting this cohort to be a high-risk group for further cognitive decline.

Factors Associated With Immediate Results of Coronary Artery Bypass Grafting in Patients With Ischemic Heart Disease in the Presence of Type 2 Diabetes

Kardiologiia ◽  
2016 ◽  
Vol 10_2016 ◽  
pp. 13-21 ◽  
Author(s):  
A.N. Sumin Sumin ◽  
N.A. Bezdenezhnyh Bezdenezhnyh ◽  
A.V. Bezdenezhnyh Bezdenezhnyh ◽  
S.V. Ivanov Ivanov ◽  
O.L. Barbarash Barbarash ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Ischemic Heart Disease ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Factors Associated
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