scholarly journals Keratosis lichenoides chronica showing significant response to acitretin

2021 ◽  
Vol 0 ◽  
pp. 1-3
Author(s):  
Neetu Bhari ◽  
Rubina Jassi ◽  
M. Ramam ◽  
G. N. Abhishek
Keyword(s):  
Significant Response

Modeling Trienzyme Biosensor at Internal Diffusion Limitation

2004 ◽  
Vol 9 (2) ◽  
pp. 139-144 ◽  
Author(s):  
J. Kulys
Keyword(s):  
Immobilized Enzymes ◽  
Internal Diffusion ◽  
Significant Response ◽  
Diffusion Limitation ◽  
Enzyme Reactions ◽  
Substrate Conversion ◽  
Apparent Stability ◽  
Biosensor Response

A model of biosensor containing three immobilized enzymes utilizing consecutive substrate conversion in the chain was developed. The modeling was performed at an internal diffusion limitation and a steadystate condition. The calculations showed that significant response of biosensors was produced if diffusion modules were larger than 1 for all enzyme reactions. Due to diffusion limitation the apparent stability of biosensor response increased many times in comparison to stability of the most labile enzyme of the chain.

scholarly journals Diagnostic performance of lung volumes in assessment of reversibility in chronic obstructive pulmonary disease

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Gamal Agmy ◽  
Manal A. Mahmoud ◽  
Azza Bahaa El-Din Ali ◽  
Mohamed Adam
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Cutoff Point ◽  
Whole Body ◽  
Significant Response ◽  
Chronic Obstructive ◽  
Lung Volumes ◽  
Obstructive Pulmonary Disease ◽  
Gold Stage ◽  
Clinically Significant

Abstract Background Reversibility measured by spirometry in chronic obstructive pulmonary disease (COPD) is defined as an increase in forced expiratory volume in first second (FEV1) that is both more than 12% and 200 mL above the pre-bronchodilator value in response to inhaled bronchodilators. FEV1 only may not fully reverberate the changes caused by reduction in air trapping or hyperinflation. To date, the studies that examined the effect of inhaled bronchodilators (BD) on residual volume (RV) and total lung capacity (TLC) are limited. This study was carried out to assess the differences between flow and volume responses after bronchodilator reversibility testing in patients with different COPD GOLD stages (GOLD stage I to stage IV). Spirometry and whole body plethysmography were done before and 15 min after inhalation of 400 μg salbutamol. Results Majority (53.3%) of cases were volume responders, 18.7% were flow responders, 20% were flow and volume responders, and 8% were non responders. Significant increase in Δ FEV1% was found in 15% of cases while 55% showed a significant increase in Δ FVC (P= < 0.001). Mean difference of Δ FVC (L) post BD was significantly increased with advancing GOLD stage (P= 0.03). A cutoff point > 20% for Δ RV% had 70% sensitivity and 60% specificity and > 12% for Δ TLC% showed 90% sensitivity and 45% specificity for prediction of clinically significant response to BD based on FEV1. A cutoff point > 18% for Δ RV% had 78% sensitivity and 29% specificity and > 14% for Δ TLC% had 50% sensitivity and 70% specificity for prediction of clinically significant response to BD based on FVC. Conclusion ΔFEV1 underestimates the true effect of bronchodilators with advancing GOLD stage. Measurement of lung volumes in addition to the standard spirometric indices is recommended when determining bronchodilator response in COPD patients.

How Effective is the Standard Dose of Disulfiram? A Review of the Alcohol-Disulfiram Reaction in Practice

1984 ◽  
Vol 144 (2) ◽  
pp. 200-202 ◽  
Author(s):  
Colin Brewer
Keyword(s):  
Side Effects ◽  
Standard Dose ◽  
Recommended Dose ◽  
Significant Response ◽  
Drinking Alcohol ◽  
Current Maximum

SummaryThe current maximum recommended dose of disulfiram, 200 mg daily, is often inadequate. Of 63 patients taking disulfiram under supervision who either risked drinking alcohol or who had a medically supervised challenge with alcohol, only half produced a significant response on a dose of 200–300 mg daily. Some patients need as much as 1.5 g daily but even at high dosage significant side effects are uncommon, reversible and rarely serious.A modification to the recommended technique for a medically supervised alcohol challenge is described, which minimises distress.

scholarly journals Liquidity and Consumption: Evidence from Three Post-Earthquake Reconstruction Programs in Italy

2020 ◽  
Vol 12 (3) ◽  
pp. 319-346
Author(s):  
Antonio Acconcia ◽  
Giancarlo Corsetti ◽  
Saverio Simonelli
Keyword(s):  
Significant Variation ◽  
Significant Response ◽  
First Year ◽  
Bank Debt ◽  
Public Funds ◽  
Italian Regions ◽  
Earthquake Reconstruction

In Italian regions hit by earthquakes, homeowners typically receive public funds to finance reconstruction. While these funds are strictly tied to reconstruction work, they are in part disbursed up front, leading to significant variation in cash on hand. We exploit this variation to study the effects of liquidity on relatively wealthy households’ consumption. We find a large and significant response in the first year that homeowners receive the cash and provide evidence that this response is driven by illiquid households with bank debt. Instead, we find no evidence that consumption responds to funds paid directly to firms, thus leaving households’ liquidity unaffected. (JEL E21, G51, H76, Q54, R31)

Race-Specific Advertising on Commercial Websites

2010 ◽  
pp. 161-179
Author(s):  
Osei Appiah ◽  
Troy Elias
Keyword(s):  
Web Sites ◽  
Product Information ◽  
Virtual Human ◽  
Significant Response ◽  
Racial Composition ◽  
Audience Response ◽  
Racially Diverse ◽  
Computer Agent ◽  
Positive Attitudes ◽  
A Site

Avatars and anthropomorphic characters by marketers are becoming more commonplace on commercial web sites. Moreover, a trend among marketers is to use ethnically ambiguous models in advertising to appeal to specific consumer segments. This study helps our understanding of not only how best to segment and appeal to racially diverse consumers but how people interact with virtual human agents in relationship to the literature on audience response to real humans. It was predicted that Blacks would respond more positively to a Black agent, than they would to either a White agent or an ethnically ambiguous agent. It was also expected that Whites would show no difference in their response based on the race of the computer agent. The findings demonstrate that Blacks had more positive attitudes toward a computer agent, had more positive attitudes toward a web site and recalled more product information from a site when the site featured a Black agent vis-à-vis a White agent. Whites showed no significant response difference concerning the agent, the brand or the site based on the racial composition of the computer agents. Interestingly, the ethnically ambiguous character was overall just as effective in persuading both White and Black browsers as were the same-race agents.

The effect of copper glycine injections on the live-weight gains of suckling beef calves

1962 ◽  
Vol 4 (3) ◽  
pp. 303-307 ◽  
Author(s):  
D. E. Morgan ◽  
A. Clegg ◽  
N. H. Brooksbank ◽  
C. T. McCrea
Keyword(s):  
Live Weight ◽  
Significant Response ◽  
Beef Calves ◽  
Weight Gains ◽  
Grazing Period ◽  
Effect Of Copper

(1) Two trials on the effect of copper glycine injections on the live-weight gains of suckling beef calves under commercial conditions are described.(2) One injection supplying 120 mg. of copper increased live-weight gains by approximately 10% during the suckling and grazing period. A second injection given two months after the first gave a further positive but not statistically significant response.

TREMORX: AN ASSISTIVE DEVICE TO IMPROVE TREMOR PATIENT WRITING CAPABILITY

2016 ◽  
Vol 78 (6-11) ◽  
Author(s):  
Z. M. Yusop ◽  
M. Z. Md. Zain ◽  
M. Hussein ◽  
A. R. Musa
Keyword(s):  
Spectral Density ◽  
Power Spectral Density ◽  
Assistive Device ◽  
Significant Response ◽  
Matlab Simulation ◽  
Hand Tremor ◽  
Power Spectral ◽  
Acceleration Data ◽  
Frequency Domains ◽  
Time And Frequency Domains

Patients with hand tremor often face difficulties in performing daily tasks using their hands, especially writing. Hence, this paper presents an inventive assistive device named as TREMORX that can assist patients in overcoming this situation by improving their handwriting legibility. TREMORX is designed to suit the patient’s handgrip and focuses more on the patient's comfort. The aim is to analyze the performance of the device based on acceleration data by implementing the power spectral density (PSD), which is focused on reduction of coherence amplitude, and displaying the signal in the time and frequency domains. The measured acceleration data are further analyzed with Matlab simulation and show a significant response. The TREMORX is designed in three different lengths of diameter and the stiffness of each one is measured. The effectiveness of the device is identified using the force sensitive resistor (FSR) to measure the force and flex sensor, as to determine the deflection. The results indicate that the patients experienced improvements in handwriting quality when using TREMORX.

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