Determination of the Optimum Fattening Period and Fattening Performance Slaughter and Carcass Characteristics of Hair Goat and Saanen × Hair Goat (G1) Crossbred Kids Fattened in Different Systems

This research was carried out to investigate the fattening performance and slaughter and carcass characteristics of Hair goat and Saanen × Hair goat (G1) crossbred kids in different fattening systems. Thirty Hair goats and 30 Saanen × Hair goat (G1) crossbred singleton male kids 2.5-3 months old and weaned were used. The kids were fattened in three different systems: intensive, semi-intensive, and extensive. Marginal value analysis was applied to determine the optimum feeding periods of the kids. In order to determine the slaughter and carcass characteristics, all the kids fattened were taken to slaughter after determining their live weight at the end of the fattening. Live weight gains after the intensive, semi-intensive, and extensive fattening were 17.83 kg, 19.39 kg, and 18.29 kg in the Hair goat kids and 17.88 kg, 18.24 kg, and 17.32 kg in the Saanen × Hair goat (G1) crossbred kids, respectively. In the same order, the average concentrate feed consumed by kids for 1 kg live weight gain was 7.55 kg, 7.28 kg, 7.00 kg and 7.07 kg. Hot carcass weights after the intensive, semi-intensive, and extensive fattening were 13.58, 14.06, and 13.02 kg in the Hair goat kids and 14.21, 15.03, and 14.06 kg in the Saanen × Hair goat (G1) crossbred kids. The Saanen × Hair goat (G1) crossbred goats increased more in live weight than the Hair goat kids and the semi-intensive fattened goats increased more in live weight than the intensive and extensive fed goats. Moreover, the optimum fattening times generally varied between the groups, but not between genotypes within the group.

A pilot study on the effect of a novel feed additive containing exogenous enzymes, acidifiers, sodium butyrate and silicon dioxide nanoparticles on selected cellular immune indices and body weight gains of calves

Introduction The rearing of calves is a difficult period for farmers due to health problems to which the animals are prone this time. Since the use of antibiotics as growth promoters has been forbidden, various innovative feed additives have been tested in many countries around the world. Material and Methods In this study, experimental (E) calves were supplemented with a novel feed additive consisting of the pancreatic-like enzymes protease and lipase, a fat-coated mixture of organic fumaric, malic, citric and sorbic acids, sodium butyrate and silicon dioxide nanoparticles. Control (C) calves received feed without additive. During the supplementation, white blood cell (WBC) counts with leukocyte differentiation, percentages of B lymphocytes and T lymphocytes and their subpopulations, phagocytic activity and oxidative burst of circulating monocytes and granulocytes were examined. Body weight (b.w.) gains of the calves were also monitored. Results The WBC counts in the E and C calves were within the reference ranges throughout the study. In the analysis of the percentages of the lymphocyte subpopulations, phagocytic activity and oxidative burst, no statistically significant differences were reported between the E and C groups. However, higher average daily body weight gains were obtained for the E calves. Conclusion The study revealed that the examined feed additive did not modulate the immune response of the calves significantly. The tendency to higher daily average b.w. gains in the E calves than in the C calves suggests a beneficial effect of this feed additive.

891. Minimum Manufacturing Costs and National Prices for Weight Loss Treatments, as Potential Mitigation for Anti-Retroviral Related Weight Gain in HIV

Background Weight gain is being observed for a wide range of antiretroviral treatments. Weight gains are higher for people taking first-line integrase inhibitor based treatments, especially those including TAF/FTC. Weight gains are higher for women and people of colour. Clinical obesity increases the risks of cardiovascular disease, diabetes, adverse birth outcomes and could lower survival rates. Anti-obesity treatments are needed to supplement lifestyle interventions and counteract progressive weight gains, but are not routinely provided as part of HIV care. Methods Costs of production for FDA-recommended weight loss treatments and anti-diabetic medications (orlistat, naltrexone-bupropion, topiramate, phentermine, semaglutide, liraglutide and metformin) were estimated using an established and published methodology based on costs of active pharmaceutical ingredients (API), extracted from the global shipping records database Panjiva. This was compared with national drug list price data from a range of low, medium, and high-income countries. Figure 1. Example of methodology for calculating the estimated minimum cost of production for orlistat Results Weight loss and anti-diabetic treatments can be generically manufactured at low per-course costs, e.g. &85 per person per year for oral treatments such as orlistat and &1 per person per month for metformin. However, prices for a year of treatment with orlistat are as high as &1,205 in the USA and as low as &11 in Vietnam. In comparison, a month of ARV treatment costs about &15 via global health institutions like CHAI. Price for injectable (subcutaneous) treatments were higher, ranging from &1,985 for liraglutide in USA to &330 in Morocco, whilst they could potentially be profitably sold for &155 for a 12-week course. No export price data was available for semaglutide. When compared against international list prices, we found wide variations between countries. Table 1. Summary of drug prices and minimum cost estimates Figure 2. Orlistat course costs in a range of countries, compared with estimated minimum cost Figure 3. Liraglutide course costs in a range of countries, compared with estimated minimum cost Conclusion We show that weight loss treatments can be manufactured and sold profitably for low prices, but have a wide price range between countries. Government and non-governmental healthcare systems should be evaluating weight loss agents for inclusion within ART programmes. Disclosures All Authors: No reported disclosures

Profitability of Using Commercial Tilapia Feed to Produce Three Different Sizes of Nile Tilapia (Oreochromis niloticus L.) Fingerlings in Ghana

Aims: To determine the profitability of using a commercial tilapia feed to produce three different size ranges (1.0-1.9, 2.0-2.9 and 5.0-5.9 g) of Nile tilapia, Oreochromis niloticus fingerlings in hapa-in-pond system. Study Design: Completely randomized design. Place and Duration of Study: The Aquaculture Research and Development Centre (ARDEC), Akosombo, of Water Research Institute (WRI) of Council for Scientific and Industrial Research (CSIR), Ghana, from March to May, 2020. Methodology: Fish growth study was carried out in three (3) fine mesh netting hapas, each of dimensions 5.0 x 2.0 x 1.2 m. Nile tilapia fry at initial mean weight 0.03 ± 0.01 g were stocked at a density of 50 fish m-2 and they were fed at 20 % body weight five times daily. The feeding of the fish continued until those in all the 3 hapas attained a mean weight of at least 5.0 g. Then the experiment was terminated and all the survived fish in each hapa were harvested, counted, and their individual body weights were measured. Growth performance indicators and profitability of producing the various size categories (1.0-1.9, 2.0-2.9 and 5.0-5.9) were determined. Results: The fry attained the target size ranges of 1.0-1.9, 2.0-2.9 and 5.0-5.9 g in 4, 6 and 9 weeks respectively. There were significant differences (ANOVA, P = 0.03) among final mean weights, weight gains, feed intakes, daily weight gains, feed efficiencies and harvested biomass among all size ranges, with those of 5.0-5.9 g being significantly higher (Tukey’s HSDT, P < 0.02). Sizes of fingerlings produced correlate positively with cost of feed used. The profit indices ranged from 2.57 to 10.22, with the highest recorded in the 1.0-1.9 g fingerlings and the least in those of 5.0-5.9 g. Conclusion: The results indicated that, at the current Nile tilapia fingerlings cost and the time taken to produce the various size categories, the 1.0-1.9 g production is the most profitable.

Effects of Using Corn Dried Distillers’ Grains with Solubles (cDDGS) as a Partial Replacement for Soybean Meal on the Outcomes of Pig Fattening, Pork Slaughter Value and Quality

The present study set out to determine the effects of incorporating cDDGS into starter, grower, and finisher diets (containing 5%, 10%, and 15% of cDDGS, respectively) on growth performance, carcass and meat quality, and cost effectiveness of pig fattening. Sixty-four pigs (mean body weight of 15.0 ± 2.1 kg) were divided into two groups (n = 32) and fed a control diet (cereal–soybean meal-based) or cDGGS-containing diets (with soybean meal partially replaced with cDDGS). Live weights of pigs as well as weight gains/daily weight gains across all fattening phases did not differ between the two groups of fattener pigs studied (p > 0.05). Addition of cDDGS decreased feed intake per pig during the grower (p < 0.05) and finisher (p < 0.01) phases, and, as a result, throughout the entire fattening period (254 vs. 245 kg for control and cDDGS groups, respectively; p < 0.01). The feed conversion ratio (FCR) for the entire fattening period was significantly less for cDDGS-fed fatteners (2.77) than for controls (2.91; p < 0.05). Carcass weights, fat thickness, and meatiness did not vary between the two groups of animals (p > 0.05). Loin depth was greater in the cDDGS group by ~5 mm (p < 0.05). Slaughter value was higher for the cDDGS group (76.1% vs. 77.0%, p < 0.05). The total cost of fattening and total cost of 1 kg of body weight decreased in cDDGS compared with the control subset of fatteners by ~7% and 8% during the grower and finisher phases, respectively (p < 0.01). The simplified direct surplus per pig was approximately 63% higher for the cDDGS group. Our results indicate that even moderate inclusion of cDDGS to concentrate mixtures (or a partial replacement of soybean meal with cDDGS) may improve FCR without any substantial changes in meat and back fat characteristics as well as significantly decrease the cost of feeding and increase the profitability of pig production.

521 Late-Breaking: Oral Mineral Drench to Reduce Morbidity and Increace Performance on Remore Summer Pastures

Economic losses due to morbidity and mortality associated with bovine respiratory disease (BRD), foot rot, pinkeye, and other health issues in yearling beef cattle are consistently over $2 billion annually. This trial was designed to test the hypothesis that yearling beef cattle individually treated with an oral micromineral drench would be associated with decreased BRD, foot rot, pinkeye, and other issues in the first 60 days with improved weight gains while grazing remote summer pastures. This trial utilized 1150 head of steers, spayed heifers, and intact heifers in areas of Idaho and Montana. Trial cattle had unknown background and nutritional history, with no metaphylaxis treatment upon arrival. Treatment data for BRD, pinkeye, and foot rot, and other abnormalities showed decreased morbidity (from 37.5–61%) in different groups P &lt; 0.234 during the first 60 days of the trial compared to the untreated cattle. Weight gains on treatment steers showed an increase 0f 18.89 lbs. in group 2 and 12.34 lbs. in group 3 (salt only) in 100 days grazing in the treatment cattle compared to the controls. The bred heifer group 1 showed showed slight weight gains of 1% and an increase pregnancy rate of 2% compared to the controls after 100 days grazing. Further trials need to be completed to determine the desired dosage using an oral mineral drench on yearling beef cattle with unknown vaccination and nutritional history.

Assessment of Silicon- and Mycorrhizae- Mediated Constitutive and Induced Systemic Resistance in Rice, Oryza sativa L., against the Fall Armyworm, Spodoptera frugiperda Smith

Induced resistance provides protection in plants against insect herbivores. Silicon and mycorrhizae often prime plant defenses and thereby enhance plant resistance against herbivores. In rice, Oryza sativa L., insect injury has been shown to induce resistance against future defoliators. However, it is unknown if silicon and mycorrhizae treatments in combination with insect injury result in greater induced resistance. Using the fall armyworm (FAW), Spodoptera frugiperda Smith, two experiments were conducted to investigate whether (1) silicon or mycorrhizae treatment alters resistance in rice and (2) induced systemic resistance in response to insect injury is augmented in silicon- or mycorrhizae- treated plants. In the first experiment, silicon treatment reduced FAW growth by 20% while mycorrhizae increased FAW growth by 8%. In the second experiment, insect injury induced systemic resistance, resulting in a 23% reduction in FAW larval weight gains on injured compared to uninjured plants, irrespective of treatment. Neither silicon nor mycorrhizae enhanced this systemic resistance in insect-injured plants. Furthermore, mycorrhizae resulted in the systemic increase of peroxidase (POD) and polyphenol oxidase (PPO) activities, and injury caused a slight decrease in these enzyme activities in mycorrhizae plants. Silicon treatment did not result in a stronger induction of POD and PPO activity in injured plants. Taken together, these results indicate a lack of silicon and mycorrhizae priming of plant defenses in rice. Regardless of injury, silicon reduced FAW weight gains by 36%. Based on these results, it appears silicon-mediated biomechanical rather than biochemical defenses may play a greater role in increased resistance against FAW in rice.

Ameliorating Effects of Different Extracts of Culinary Mushroom Species on the Production Performance of Healthy and Eimeria Infected Commercial Broiler Birds

In this research, three edible mushroom species including Pleurotus (P.) ostreatus, P. sajor-caju and Lentinus (L.) edodes were processed for hot water, methanolic and polysaccharide extracts. These extracts were administered to commercial broiler birds. Production performance was determined as weight gains and feed conversion ratios (FCR) in healthy birds on weekly basis. Further, groups were subjected to oral Eimeria infection and weight gains were monitored from days 4 to 12 post inoculation. Study revealed significantly higher (P < 0.05) weight gains in experimental groups given different mushroom extracts during 4th, 5th and 6th weeks of experiment in comparison to control. Feed conversion ratios observed in the control groups were significantly higher (P < 0.05) as compared to experimental groups especially methanolic extracts of all three mushroom species during 5th and 6th weeks of the experiment. After Eimeria inoculation, weight gains of the experimental groups given different mushroom extracts were significantly higher (P < 0.05) on 10th, 11th and 12th day. Results concluded that aqueous, methanolic and polysaccharide extracts of P. ostreatus, P. sajor-caju and L. edodes had potential to improve the production in healthy birds and may also enhance the weights in commercial broiler birds suffering from Eimeria infection. © 2021 Friends Science Publishers