Sudden Vision Loss in a Diabetic Patient with Lipemia Retinalis and Optic Atrophy

BackGround: Diabetes mellitus results in considerable morbidity and mortality, affecting about 180 million people worldwide.The primary complications of diabetes due to damage in small blood vessels include damage to the eyes, kidneys,and nerves.Damage to the eyes,known as diabetic retinopathy,is caused by damage to the blood vessels in the retina of the eye,and can result in gradual vision loss and eventual blindness.Usually,a diabetic patient seeks the advice of ophthalmologist only when the ocular condition is in the advance stage.It is therefore,essential to examine the fundus and anterior segment of eye of every diabetic patient periodically at regular intervals,to detect early cases.This study was done to analyze the relation of duration and glycaemic control of diabetes to ocular manifestations among patients attending AGMC & GBP Hospital. Materials and Methods: This crossectional study was carried out on patients of Department of Ophthalmology at AGMC & GBP Hospital from October 2017 to April 2019.A total 85 adult subject (both male and females) of all age group were included in this study.Detailed eye examination and blood investigation like blood sugar and HbA1C was done. Results: The study showed that 26 (30.6%) patients had mild NPDR, 11(12.9%) patients had moderate NPDR, 8(9.4%) patients had severe NPDR, 2(2.4%) patients had PDR and 38(44.7%) patients had normal retina in right eye. 22(25.9%) patients had mild NPDR,10(11.8%) patients had moderate NPDR,7(8.2%) patients had severe NPDR,1(1.2%) patient had PDR and 45(52.9%) patients had no retinopathy left eye.

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In a diabetic patient, each vision loss is not dependent on diabetes: case report, giant suprasellar mass, menengiomjiom

Journal of Health Sciences and Medicine ◽

10.32322/jhsm.460227 ◽

2019 ◽

Author(s):

NAZLIGÜL KARAÜZÜM YALÇIN

Keyword(s):

Case Report ◽

Diabetic Patient ◽

Vision Loss ◽

Diabetes Case

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Orbital apex syndrome: An unusual complication of invasive mucormycosis

Proceedings of Singapore Healthcare ◽

10.1177/2010105818758089 ◽

2018 ◽

Vol 27 (4) ◽

pp. 287-289 ◽

Cited By ~ 1

Author(s):

W J Quah ◽

M Gunavathy

Keyword(s):

Diabetic Patient ◽

Antimicrobial Therapy ◽

Multidisciplinary Approach ◽

Vision Loss ◽

Surgical Intervention ◽

Unusual Complication ◽

Orbital Apex ◽

Orbital Apex Syndrome ◽

Diagnostic Challenge ◽

Rare Manifestation

Orbital apex syndrome is a rare manifestation of invasive mucormycosis. We report a case of orbital apex syndrome in a diabetic patient which not only posed a diagnostic challenge but also required a multidisciplinary approach in treatment and management. Prompt imaging followed by early initiation of antimicrobial therapy along with timely surgical intervention were integral in preventing further complications and reducing mortality. However, despite these measures, the patient sustained partial vision loss due to endophthalmitis as a complication.

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Hereditary Optic Neuropathy

Neuro-Ophthalmology ◽

10.1093/med/9780195390841.003.0005 ◽

2011 ◽

pp. 25-28

Author(s):

Matthew J. Thurtell ◽

Robert L. Tomsak ◽

Robert B. Daroff

Keyword(s):

Optic Neuropathy ◽

Optic Atrophy ◽

Vision Loss ◽

Treatment Options ◽

Monocular Vision ◽

Leber’S Hereditary Optic Neuropathy ◽

Leber's Hereditary Optic Neuropathy ◽

Central Vision Loss ◽

Promising Treatment ◽

Hereditary Optic Neuropathy

Monocular and binocular vision loss can occasionally be caused by hereditary optic neuropathy. While progressive painless binocular central vision loss is characteristic of dominant optic atrophy, acute painless monocular vision loss is characteristic of Leber’s hereditary optic neuropathy. We discuss the clinical features and evaluation of Leber’s hereditary optic neuropathy and briefly mention promising treatment options.

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Refractory Giant Cell Arteritis Complicated by Vision Loss From Optic Atrophy and Maculopathy Associated With Pachymeningitis

Journal of Neuro-Ophthalmology ◽

10.1097/wno.0000000000000566 ◽

2018 ◽

Vol 38 (1) ◽

pp. 17-23 ◽

Cited By ~ 2

Author(s):

Jorge A. Uribe ◽

Ishita Aggarwal ◽

Juthamat Witthayaweerasak ◽

Y. Joyce Liao ◽

Gerald J. Berry ◽

...

Keyword(s):

Giant Cell Arteritis ◽

Giant Cell ◽

Optic Atrophy ◽

Vision Loss

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Lipemia Retinalis, Macular Edema, and Vision Loss in a Diabetic Patient with a History of Type IV Hypertriglyceridemia and Pancreatitis

Case Reports in Ophthalmology ◽

10.1159/000493384 ◽

2018 ◽

Vol 9 (3) ◽

pp. 425-430 ◽

Cited By ~ 2

Author(s):

John W. Hinkle ◽

Nidhi Relhan ◽

Harry W. Flynn Jr.

Keyword(s):

Visual Acuity ◽

Diabetic Patient ◽

Macular Edema ◽

Vision Loss ◽

Elevated Serum ◽

Lipid Lowering ◽

Lipid Lowering Therapy ◽

Serum Triglycerides ◽

Type Iv ◽

History Of

Background: Lipemia retinalis is a rare but known complication of elevated serum triglycerides. This case describes the clinical course of a diabetic patient who presented with lipemia retinalis and macular edema, which responded to systemic and local treatments. Case Report: A 40-year-old female with a history of type II diabetes mellitus, hypertriglyceridemia, and pancreatitis presented with decreased vision in the left eye. She had peripapillary and macular edema, intraretinal hemorrhages, and prominent exudates in the setting of lipemia retinalis due to type IV hypertriglyceridemia. She was treated with serial intravitreal bevacizumab injections for macular edema and systemic lipid lowering therapy, and her visual acuity improved back to baseline. Conclusions: In the setting of lipemia retinalis and hypertriglyceridemia, the current patient developed macular edema and vision loss. The macular edema was treated with intravitreal injections of bevacizumab, and the patient experienced a rapid recovery of visual acuity.

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NF1 optic pathway glioma: analyzing risk factors for visual outcome and indications to treat

Neuro-Oncology ◽

10.1093/neuonc/noaa153 ◽

2020 ◽

Author(s):

Amedeo A Azizi ◽

David A Walker ◽

Jo-Fen Liu ◽

Astrid Sehested ◽

Timothy Jaspan ◽

...

Keyword(s):

Risk Factors ◽

Optic Atrophy ◽

Vision Loss ◽

Multivariable Analysis ◽

Visual Outcome ◽

Optic Pathway Glioma ◽

Optic Pathway ◽

Visual Outcomes ◽

Treatment Indications ◽

Tumor Involvement

Abstract Background The aim of the project was to identify risk factors associated with visual progression and treatment indications in pediatric patients with neurofibromatosis type 1 associated optic pathway glioma (NF1-OPG). Methods A multidisciplinary expert group consisting of ophthalmologists, pediatric neuro-oncologists, neurofibromatosis specialists, and neuro-radiologists involved in therapy trials assembled a cohort of children with NF1-OPG from 6 European countries with complete clinical, imaging, and visual outcome datasets. Using methods developed during a consensus workshop, visual and imaging data were reviewed by the expert team and analyzed to identify associations between factors at diagnosis with visual and imaging outcomes. Results Eighty-three patients (37 males, 46 females, mean age 5.1 ± 2.6 y; 1–13.1 y) registered in the European treatment trial SIOP LGG-2004 (recruited 2004–2012) were included. They were either observed or treated (at diagnosis/after follow-up). In multivariable analysis, factors present at diagnosis associated with adverse visual outcomes included: multiple visual signs and symptoms (adjusted odds ratio [adjOR]: 8.33; 95% CI: 1.9–36.45), abnormal visual behavior (adjOR: 4.15; 95% CI: 1.20–14.34), new onset of visual symptoms (adjOR: 4.04; 95% CI: 1.26–12.95), and optic atrophy (adjOR: 3.73; 95% CI: 1.13–12.53). Squint, posterior visual pathway tumor involvement, and bilateral pathway tumor involvement showed borderline significance. Treatment appeared to reduce tumor size but improved vision in only 10/45 treated patients. Children with visual deterioration after primary observation are more likely to improve with treatment than children treated at diagnosis. Conclusions The analysis identified the importance of symptomatology, optic atrophy, and history of vision loss as predictive factors for poor visual outcomes in children with NF1-OPG.

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