Multimodal approach in the diagnosis of changes in the organ of vision at atherosclerosis

2021 ◽  
pp. 32-36
Author(s):  
M.S. Kasimova ◽  
◽  
D.K. Mahkamova ◽  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Early Diagnosis ◽  
Key Words ◽  
Sharp Decrease ◽  
Multimodal Approach ◽  
Vascular Plexus ◽  
Group I ◽  
Atherosclerosis Development ◽  
Vascular Plexuses

Purpose. To study the parameters of OCTA with changes in the organ of vision against the background of atherosclerosis. Results. The registration of OCTA in patients of group I, a decrease in the density of capillaries of the superficial vascular network was 15% and amounted to 45.21±2.62% (p<0.05), of the deep vascular plexus by 19%, which amounted to 45.89±2.71% (p<0.05). Analysis of OCTA in patients of group II revealed a sharp decrease (by 48%) in the density of capillaries in both the superficial and deep vascular plexuses of the retina, which amounted to 33.91±3.01% (p<0.05) and 33.65±2.89% (p<0.05), respectively. Conclusion. The use of OCTA allows to detect changes in hemoperfusion in all layers of the retina and optic nerve in the early stages of atherosclerosis development, which will allow early diagnosis and monitoring of the disease. Key words: organ of vision, atherosclerosis, optical coherence tomography with angiography.

scholarly journals MULTIMODAL METHODS IN THE DIAGNOSIS OF CHANGES IN THE ORGAN OF VISION AT ATHEROSCLEROSIS

2020 ◽  
pp. 411-418
Author(s):  
D. K. Makhkamova
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Sharp Decrease ◽  
Optical Coherence ◽  
Group I ◽  
Target Organs ◽  
Deep Layers ◽  
Group Ii ◽  
Vascular Plexuses ◽  
Multimodal Methods

Background. The study of the parameters of optical coherence tomography with angiography (OCTA) broadens the understanding of the state of hemodynamics for the early detection of vascular disorders of the organ of vision in atherosclerosis (AS). Purpose. To study the parameters of OCTA with changes in the organ of vision against the background of AS. Material and methods. 26 patients (41 eyes) with changes in the organ of vision in AS. The age contingent of patients ranged from 32 to 78 years, the average age was 47.5 ± 2.0 g, of which 10 were women, 16 men. Depending on the damage to target organs, all patients were conditionally divided into 2 groups: group I (19 eyes) included patients without damage, and group II (22 eyes) consisted of patients with target organs damage. Results. The registration of OCTA in patients of group I, a decrease in the density of capillaries of the superficial vascular network was 15% and amounted to 45.21 ± 2.62% (p <0.05), of the deep vascular plexus by 19%, which amounted to 45.89 ± 2 , 71% (p <0.05). In the macular region, the area of the hypoperfused retina was 1.07 ± 0.14 mm2 (p <0.05). In the region of the optic nerve disc, areas of hypoperfusion were noted in the superficial layers in 7 eyes and in the deep layers in 4 eyes. Analysis of OCTA in patients of group II revealed a sharp decrease (by 48%) in the density of capillaries in both the superficial and deep vascular plexuses of the retina, which amounted to 33.91 ± 3.01% (p <0.05); 33.65 ± 2.89% (p <0.05), respectively. In the macular region, the area of the non-perfused retina was 2.19 ± 0.21 mm2 (p <0.05). In the area of the optic nerve disc, areas of nonperfusion were noted both in the surface layers and in the deep layers in 4 eyes. Conclusion. The use of OCTA allows to detect changes in hemoperfusion in all layers of the retina and optic nerve in the early stages of AS development, which will allow early diagnosis and monitoring of the disease. KEY WORDS: optical coherence tomography with angiography, ischemic diseases, organ of vision, atherosclerosis, hemoperfusion, vascular plexuses, retina and optic nerve.

scholarly journals The value of the added diffusion-weighted images to multiparametric MRI in the early diagnosis of uterine cervix cancers and nodal assessment

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Nasr Mohamed Osman ◽  
Mohamed Aboul-fotouh Mourad
Keyword(s):  
Early Diagnosis ◽  
Diagnostic Accuracy ◽  
Multiparametric Mri ◽  
Lesion Group ◽  
Cervical Lesions ◽  
Adc Value ◽  
Diffusion Weighted ◽  
Group I ◽  
Malignant Lesions ◽  
The Mean

Abstract Background Cervical cancer still one of the most common causes of tumor-related death in developing countries presented in younger women. In this study, we aimed to evaluate the value of diffusion-weighted MRI in early diagnosis of malignant cervical lesions, to assess metastatic adenopathy, peritoneal dissemination, and possible tumor recurrence, and determine treatment response. This study included 60 patients with abnormal vaginal bleeding and suspected cervical lesion by US. A histopathological biopsy was done. Pelvic MR with DWI and dynamic contrast-enhanced MRI were done for all patients. Results According to the histopathological findings, we divided our studied 60 patents into two groups: group I, malignant lesions (46 lesions; 76.7%), and group II, benign lesions (14 lesions; 23.3%). Multiparametric MRI could detect all cervical lesions but with poor pathologic characterization, achieving 72.37% sensitivity, 37.50% specificity, 63.33% accuracy, 76.19% PPV, and 33.33% NPV. When compared with DWI with ADC value measurements at high b value (b = 800) to MRI exam, it showed a higher diagnostic accuracy with good lesion pathological characterization that achieved 95.65% sensitivity, 71.43% specificity, 90% accuracy, 91.67 PPV, and 83.33% NPV. The mean ADC value for malignant lesions was 0.86–1.1, mean = 0.92 ± 0.71 × 10−3 mm2/s, while the mean ADC value in the benign lesion group was 1.18 ± 0.1 × 10–3 mm2/s. Conclusion Comparing DWI with ADC values measurements at high b value to the multiparametric MRI examination of the female pelvis increases the sensitivity, specificity, and diagnostic accuracy of characterization and early diagnosis of cervical malignant focal lesions and reduces the need for intravenous contrast administration.

Retinal microcirculation abnormalities in patients with systemic sclerosis: an explorative optical coherence tomography angiography study

Rheumatology ◽  
2021 ◽  
Author(s):  
Adriano Carnevali ◽  
Giuseppe Giannaccare ◽  
Valentina Gatti ◽  
Caterina Battaglia ◽  
Giorgio Randazzo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Flow Index ◽  
Digital Ulcers ◽  
Optical Coherence ◽  
Vascular Abnormalities ◽  
Capillary Plexus ◽  
Retinal Microcirculation ◽  
Vascular Plexuses

Abstract Objectives To investigate subclinical and clinical abnormalities in retinal and choroidal vascular plexuses in patients with SSc by means of optical coherence tomography angiography (OCT-A). Methods A total of 20 consecutive SSc patients were recruited and compared with 20 healthy subjects. Quantitative analysis of vessel density (VD), choriocapillaris plexus flow index (CCP-FI) and choroidal vascularity index were performed on OCT-A images in the superficial capillary plexus (SCP), deep capillary plexus (DCP) and CCP for all patients. Images were further reviewed by two independent readers for the assessment of qualitative abnormalities, including tortuosity, rarefaction areas, megacapillaries and macular-foveal capillaries. Results The DCP-VD in the whole scan and in the perifoveal, superior, inferior, nasal and temporal regions was significantly lower in the SSc group. The CCP-FI was significantly higher in SSc patients. When comparing SSc patients with and without digital ulcers, significantly decreased SCP-VD was demonstrated in the whole, perifoveal, superior, inferior, temporal and nasal regions. No difference in any of the OCT-A parameters was observed when comparing patients with and without interstitial lung disease. Qualitative analysis of OCT-A revealed at least one abnormality in 95% of patients. Conclusion We showed the ability of OCT-A to disclose early ocular vascular abnormalities in patients with SSc. Our results may represent a hypothesis-generating basis for exploring the potential role of OCT-A in diagnosis, monitoring and prognosis stratification in SSc.

scholarly journals Topography and volume measurements of the optic nerve using en-face optical coherence tomography

2001 ◽  
Vol 9 (10) ◽  
pp. 533 ◽  
Author(s):  
John A. Rogers ◽  
Adrian Gh. Podoleanu ◽  
George M. Dobre ◽  
David A. Jackson ◽  
Fred W. Fitzke
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optical Coherence ◽  
En Face ◽  
Volume Measurements

scholarly journals Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

2016 ◽  
Vol 57 (9) ◽  
pp. OCT413 ◽  
Author(s):  
Anant Agrawal ◽  
Jigesh Baxi ◽  
William Calhoun ◽  
Chieh-Li Chen ◽  
Hiroshi Ishikawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence

NattoKing K87 soybean

1991 ◽  
Vol 71 (3) ◽  
pp. 863-864
Author(s):  
N. R. Bradner ◽  
R. D. Simpson ◽  
A. A. Hadlock
Keyword(s):  
Glycine Max ◽  
Key Words ◽  
Maturity Group ◽  
Group I ◽  
Glycine Max L ◽  
Cultivar Description

NattoKing K87, a Maturity Group I soybean (Glycine max (L.) Merr.) cultivar, yields more, has smaller seeds, lodges less and matures later than Canatto. Key words: Glycine max, NattoKing K87 cultivar, cultivar description, soybean

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