scholarly journals MULTIMODAL METHODS IN THE DIAGNOSIS OF CHANGES IN THE ORGAN OF VISION AT ATHEROSCLEROSIS

2020 ◽  
pp. 411-418
Author(s):  
D. K. Makhkamova
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Sharp Decrease ◽  
Optical Coherence ◽  
Group I ◽  
Target Organs ◽  
Deep Layers ◽  
Group Ii ◽  
Vascular Plexuses ◽  
Multimodal Methods

Background. The study of the parameters of optical coherence tomography with angiography (OCTA) broadens the understanding of the state of hemodynamics for the early detection of vascular disorders of the organ of vision in atherosclerosis (AS). Purpose. To study the parameters of OCTA with changes in the organ of vision against the background of AS. Material and methods. 26 patients (41 eyes) with changes in the organ of vision in AS. The age contingent of patients ranged from 32 to 78 years, the average age was 47.5 ± 2.0 g, of which 10 were women, 16 men. Depending on the damage to target organs, all patients were conditionally divided into 2 groups: group I (19 eyes) included patients without damage, and group II (22 eyes) consisted of patients with target organs damage. Results. The registration of OCTA in patients of group I, a decrease in the density of capillaries of the superficial vascular network was 15% and amounted to 45.21 ± 2.62% (p <0.05), of the deep vascular plexus by 19%, which amounted to 45.89 ± 2 , 71% (p <0.05). In the macular region, the area of the hypoperfused retina was 1.07 ± 0.14 mm2 (p <0.05). In the region of the optic nerve disc, areas of hypoperfusion were noted in the superficial layers in 7 eyes and in the deep layers in 4 eyes. Analysis of OCTA in patients of group II revealed a sharp decrease (by 48%) in the density of capillaries in both the superficial and deep vascular plexuses of the retina, which amounted to 33.91 ± 3.01% (p <0.05); 33.65 ± 2.89% (p <0.05), respectively. In the macular region, the area of the non-perfused retina was 2.19 ± 0.21 mm2 (p <0.05). In the area of the optic nerve disc, areas of nonperfusion were noted both in the surface layers and in the deep layers in 4 eyes. Conclusion. The use of OCTA allows to detect changes in hemoperfusion in all layers of the retina and optic nerve in the early stages of AS development, which will allow early diagnosis and monitoring of the disease. KEY WORDS: optical coherence tomography with angiography, ischemic diseases, organ of vision, atherosclerosis, hemoperfusion, vascular plexuses, retina and optic nerve.

Multimodal approach in the diagnosis of changes in the organ of vision at atherosclerosis

2021 ◽  
pp. 32-36
Author(s):  
M.S. Kasimova ◽  
◽  
D.K. Mahkamova ◽  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Early Diagnosis ◽  
Key Words ◽  
Sharp Decrease ◽  
Multimodal Approach ◽  
Vascular Plexus ◽  
Group I ◽  
Atherosclerosis Development ◽  
Vascular Plexuses

Purpose. To study the parameters of OCTA with changes in the organ of vision against the background of atherosclerosis. Results. The registration of OCTA in patients of group I, a decrease in the density of capillaries of the superficial vascular network was 15% and amounted to 45.21±2.62% (p<0.05), of the deep vascular plexus by 19%, which amounted to 45.89±2.71% (p<0.05). Analysis of OCTA in patients of group II revealed a sharp decrease (by 48%) in the density of capillaries in both the superficial and deep vascular plexuses of the retina, which amounted to 33.91±3.01% (p<0.05) and 33.65±2.89% (p<0.05), respectively. Conclusion. The use of OCTA allows to detect changes in hemoperfusion in all layers of the retina and optic nerve in the early stages of atherosclerosis development, which will allow early diagnosis and monitoring of the disease. Key words: organ of vision, atherosclerosis, optical coherence tomography with angiography.

scholarly journals Optical coherence tomography can be used in evaluation of morphological and functional results after successful rhegmatogenous retinal detachment surgery with different tamponade agents

2015 ◽  
Vol 8 (1) ◽  
pp. 5-11
Author(s):  
Tat'yana Andreevna Avanesova
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Detachment ◽  
Rhegmatogenous Retinal Detachment ◽  
Silicone Oil ◽  
Strong Association ◽  
Functional Results ◽  
Optical Coherence ◽  
Retinal Detachment Surgery ◽  
Group I ◽  
Group Ii

Background: Optical coherence tomography (OCT) findings are helpful in assessing the cause of reduced visual acuity (VA) after successful rhegmatogenous retinal detachment (RRD) surgery. Objective: To study anatomical and functional results after successful RRD surgery with gas-air mixture or silicone oil (SO) tamponade using OCT. Materials and methods. 70 patients were divided into 2 groups: group I (n = 34) - gas-air mixture tamponade; group II (n = 36) - SO tamponade. At baseline, were no significant differences by gender, age and VA between the groups. Follow-up was 12 months after the surgery. OCT was performed with the Cirrus HD-OCT 4000, CARL ZEISS MEDITEC, USA. Results: VA increased significantly in both groups. Regression analysis showed lower VA in group II and statistically significant association between VA and IS/OS and ELM defects. Сonclusions. There is a strong association of disruption of the IS/OS and ELM with reduced vision after successful retinal detachment surgery. Gas-air mixture tamponade showed some benefits in comparison with SO tamponade.

Evaluation of microvascular changes with the use of OCT-A in macular teleangioectasias of type 2

2021 ◽  
pp. 193-195
Author(s):  
S.M. Purshak ◽  
◽  
I.A. Melikhova ◽  
L.N. Boriskina ◽  
S.V. Balalin ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Quantitative Assessment ◽  
Control Group ◽  
Optical Coherence ◽  
Group Iii ◽  
Microvascular Changes ◽  
Macular Telangiectasia ◽  
Group I ◽  
Group Ii

Purpose. To study the parameters of microvascular changes in the retina with their quantitative assessment by OCT-angiography. Materials and methods. The control group is consisted of 20 healthy eyes (group I), 20 eyes with type 2 macular telangioectasia without CNV (group II), and 20 eyes with macular telangiectasia with CNV (group III). All patients underwent optical coherence tomography with the function of angiography. Results. FAZ parameters: Group I 0.234±0.08, group II 0.357±0.05, group III 0.339±0.11. PERIM FAZ: I group 1.857±0.34, II group 2,971±0.36, III group 2.853±0.56. FD index: I group 53.48±2.73, II group 52.83±4.66, III group 54.18±6.39. Conclusion. In the course of the study, statistically significant increases were detected in the parameters of the FAZ and PERIM ingroup II and III compared to the control group. Key words: macular telangioectasia, MacTel, optical coherence tomography with angiography function, OCT-A, FAZ, PERIM, FD.

Retinal microcirculation abnormalities in patients with systemic sclerosis: an explorative optical coherence tomography angiography study

Rheumatology ◽  
2021 ◽  
Author(s):  
Adriano Carnevali ◽  
Giuseppe Giannaccare ◽  
Valentina Gatti ◽  
Caterina Battaglia ◽  
Giorgio Randazzo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Flow Index ◽  
Digital Ulcers ◽  
Optical Coherence ◽  
Vascular Abnormalities ◽  
Capillary Plexus ◽  
Retinal Microcirculation ◽  
Vascular Plexuses

Abstract Objectives To investigate subclinical and clinical abnormalities in retinal and choroidal vascular plexuses in patients with SSc by means of optical coherence tomography angiography (OCT-A). Methods A total of 20 consecutive SSc patients were recruited and compared with 20 healthy subjects. Quantitative analysis of vessel density (VD), choriocapillaris plexus flow index (CCP-FI) and choroidal vascularity index were performed on OCT-A images in the superficial capillary plexus (SCP), deep capillary plexus (DCP) and CCP for all patients. Images were further reviewed by two independent readers for the assessment of qualitative abnormalities, including tortuosity, rarefaction areas, megacapillaries and macular-foveal capillaries. Results The DCP-VD in the whole scan and in the perifoveal, superior, inferior, nasal and temporal regions was significantly lower in the SSc group. The CCP-FI was significantly higher in SSc patients. When comparing SSc patients with and without digital ulcers, significantly decreased SCP-VD was demonstrated in the whole, perifoveal, superior, inferior, temporal and nasal regions. No difference in any of the OCT-A parameters was observed when comparing patients with and without interstitial lung disease. Qualitative analysis of OCT-A revealed at least one abnormality in 95% of patients. Conclusion We showed the ability of OCT-A to disclose early ocular vascular abnormalities in patients with SSc. Our results may represent a hypothesis-generating basis for exploring the potential role of OCT-A in diagnosis, monitoring and prognosis stratification in SSc.

scholarly journals Topography and volume measurements of the optic nerve using en-face optical coherence tomography

2001 ◽  
Vol 9 (10) ◽  
pp. 533 ◽  
Author(s):  
John A. Rogers ◽  
Adrian Gh. Podoleanu ◽  
George M. Dobre ◽  
David A. Jackson ◽  
Fred W. Fitzke
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optical Coherence ◽  
En Face ◽  
Volume Measurements

scholarly journals Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

2016 ◽  
Vol 57 (9) ◽  
pp. OCT413 ◽  
Author(s):  
Anant Agrawal ◽  
Jigesh Baxi ◽  
William Calhoun ◽  
Chieh-Li Chen ◽  
Hiroshi Ishikawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence
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