Atypical brain lesions in reactivation of Chagas disease in a delayed diagnosis AIDS patient

2016 ◽  
Author(s):  
Laura Alonso Acero
Keyword(s):  
Chagas Disease ◽  
Delayed Diagnosis ◽  
Brain Lesions

scholarly journals Participation of Central Muscarinic Receptors on the Nervous Form of Chagas Disease in Mice Infected via Intracerebroventricular with Colombian Trypanosoma cruzi Strain

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 121
Author(s):  
Gabriela Maira Pereira de Assis ◽  
Micheline Freire Donato ◽  
Matheus Marques Milagre ◽  
Samantha Ribeiro Béla ◽  
Mayra Fernanda Ricci ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Chagas Disease ◽  
Muscarinic Acetylcholine Receptor ◽  
Cholinergic Receptor ◽  
Receptor Activation ◽  
Brain Lesions ◽  
Behavioral Alterations ◽  
Immune Mediated ◽  
Agonist And Antagonist ◽  
Central Muscarinic Receptors

Acute chagasic encephalitis is a clinically severe central nervous system (CNS) manifestation. However, the knowledge of the nervous form of Chagas disease is incomplete. The role of the muscarinic acetylcholine receptor (mAChR) on mice behavior and brain lesions induced by Trypanosoma cruzi (Colombian strain) was herein investigated in mice treated with the mAChR agonist and antagonist (carbachol and atropine), respectively. Immunosuppressed or non-immunosuppressed mice were intracerebroventricularly (icv) or intraperitoneally (ip) infected. All groups were evaluated 15 d.p.i. (days post infection). Intraperitoneally infected animals had subpatent parasitemia. Patent parasitemia occurred only in icv infected mice. The blockade of mAChR increased the parasitemia, parasitism and lesions compared to its activation. Infected not treated (INT ip) mice did not present meningitis and encephalitis, regardless of immunosuppression. INT icv brains presented higher cellularity, discrete signs of cellular degeneration, frequent presence of parasites and focal meningitis. The immunosuppressed atropine + icv mice presented increased intracellular parasitism associated with degenerative parenchymal changes, while carbachol + icv mice presented discrete meningitis, preservation of the cortex and absence of relevant parasitism. Cholinergic receptor blockage increased impairment of coordination vs. receptor activation. Muscarinic cholinergic pathway seems to be involved in immune mediated cell invasion events while its blockade favored infection evolution, brain lesions, and behavioral alterations.

Early-Childhood Education for the Developmentally Delayed: Diagnosis, Intervention, and Evaluation

1979 ◽  
Vol 10 (2) ◽  
pp. 81-92
Author(s):  
Susan Freedman Gilbert
Keyword(s):  
Early Childhood ◽  
Early Childhood Education ◽  
School Children ◽  
Developmental Delays ◽  
Delayed Diagnosis ◽  
Language Impairments ◽  
Developmentally Delayed ◽  
Speech And Language ◽  
Childhood Education

This paper describes the referral, diagnostic, interventive, and evaluative procedures used in a self-contained, behaviorally oriented, noncategorical program for pre-school children with speech and language impairments and other developmental delays.

706 B-type natriuretic peptide (BNP) and ventricular arrhythmias in Chagas disease

2007 ◽  
Vol 6 (1) ◽  
pp. 155-156
Author(s):  
J MARQUES ◽  
A KANSKY ◽  
I MENDOZA ◽  
L LOPEZGOMEZ ◽  
F MOLEIRO ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Chagas Disease ◽  
Ventricular Arrhythmias

Those Childhood Brain Lesions

1981 ◽  
Vol 26 (8) ◽  
pp. 641-642 ◽  
Author(s):  
James C. Reed
Keyword(s):  
Brain Lesions

Education Modulates the Relationship between White Matter Brain Lesions and Cognition

2003 ◽  
Author(s):  
C. Dufouil ◽  
◽  
A. Alperovitch ◽  
C. Tzourio
Keyword(s):  
White Matter ◽  
Brain Lesions ◽  
The Relationship

Chagas Disease After Organ Transplantation - Los Angeles, California, 2006

2006 ◽  
Author(s):  
L. Mascola ◽  
B. Kubak ◽  
S. Radhakrishna ◽  
T. Mone ◽  
R. Hunter ◽  
...  
Keyword(s):  
Los Angeles ◽  
Organ Transplantation ◽  
Chagas Disease

Diagnostic inferences of brain lesions based on psychological test results.

1966 ◽  
Vol 7a (4, Suppl) ◽  
pp. 368-383 ◽  
Author(s):  
Ralph M. Reitan
Keyword(s):  
Brain Lesions ◽  
Psychological Test ◽  
Test Results

Cha 912, a new human cross-reactive antigen in Chagas' disease

1997 ◽  
Vol 56 (1-3) ◽  
pp. 429
Author(s):  
C Rodríguez
Keyword(s):  
Chagas Disease
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