ACUTE ISCHEMIC STROKE IN YOUNG ADULTS: DO THE RISK FACTORS DIFFER FROM THE ADULTS PATIENT?

Author(s):  
Jom Suwanno
Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Elizabeth M Aradine ◽  
Yan Hou ◽  
Kathleen A Ryan ◽  
Prachi Mehndiratta ◽  
Michael S Phipps ◽  
...  

Introduction: Few studies have compared the proportion of ischemic strokes attributable to traditional vascular risk factors (population-attributable risk percent or PAR%) between genders and races. The PAR% is a function of the population prevalence and strength of association of a risk factor. Methods: A population-based case-control study of ischemic stroke in young adults ages 18-49 in the Baltimore-Washington region was used to study the prevalence, odds ratios, and PAR% of hypertension, diabetes, and smoking among blacks and whites. Logistic regression was used to calculate age-adjusted odds ratios. All analyses were stratified by gender. Results: There were 1044 cases and 1099 controls. Of the cases, 47% were black, 54% were women. Roughly a quarter to a third of all strokes in women were attributable to smoking. Due to the higher prevalence of hypertension and a higher odds ratio for hypertension in black men (OR 3.9, 95% CI 2.6-5.9) compared to white men (OR 1.8, 95% CI 1.3-2.6), there was a much higher PAR% for hypertension among black men than white men. See Table 1 for prevalence and Table 2 for PAR% stratified by gender and race. Conclusion: Traditional vascular risk factors have the potential to explain a high proportion of ischemic stroke in young adults. The high proportion of strokes in women attributable to smoking underscores the need for targeted smoking cessation interventions in this population. Diabetes and, especially, hypertension are important contributors to the excess population burden of ischemic stroke among blacks. These findings support the value of early screening and treatment for hypertension in young blacks.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Liming Zhang ◽  
Xiaoyu Zhang ◽  
Huaqiang Li ◽  
Gang Chen ◽  
Meijia Zhu

2020 ◽  
Vol 29 (12) ◽  
pp. 105270
Author(s):  
Amir Shaban ◽  
Vaelan Molian ◽  
Aayushi Garg ◽  
Kaustubh Limaye ◽  
Enrique C. Leira ◽  
...  

2020 ◽  
Vol 10 (5) ◽  
pp. 203-206 ◽  
Author(s):  
Fahimeh Vahabizad ◽  
Maryam Sharifian Dorche ◽  
Pegah Mohammadi ◽  
Kasra Khatibi ◽  
Ashkan Mowla

2019 ◽  
Vol 2 (1) ◽  
pp. 32-39
Author(s):  
Madhavi Karri ◽  
Balakrishnan Ramasamy

Background: Ischemic stroke in young adults is becoming a rising concern with the increase in vulnerability to traditional risk factors and changing lifestyles. Aim: An overview of risk factors, classification, and clinical outcome of ischemic stroke in young adults (19 to 45 years) has been presented. Methods: Data fulfilling the study criteria from the stroke registry between June 2014 and June 2017 were collected, and a detailed proforma was taken that included history, clinical examination, and routine investigations. Selective investigations such as prothrombotic workup and 24-hour Holter monitoring were performed. Stroke was subclassified using the Trial of Org 10172 in Acute Stroke Treatment criteria. National Institute of Health Stroke Scale (NIHSS) scores at baseline and the modified Rankin score (mRS) scoring after 3 months of patients’ admission were calculated. Results: Out of 223 identified cases of ischemic stroke in young adults, 186 (83.4%) were taken for analysis, constituting 7.3% of the total stroke population of 3,059. Among the cases taken for analysis, 137 were males and 49 were females. A total of 150 patients were among the age group of 36 to 45 years. Dyslipidemia, smoking, and alcohol consumption were prevalent in the study group. Atherosclerotic strokes were predominant in the study population. NIHSS scores at admission had a significant impact on mRS scores after 3 months. In this study, only 4% reported the recurrence of stroke, whereas mortality was about 0.02%. Conclusions: Workup required for ischemic stroke in young adults has always been a diagnostic challenge for physicians who treat the stroke patients, and this must be optimized in all health care centers. Despite extensive workup, 23.66% participants were found to be cryptogenic in this study. The clinical outcome was good in this study with less mortality observed.


2020 ◽  
Vol 417 ◽  
pp. 117068
Author(s):  
Yu Kono ◽  
Yuka Terasawa ◽  
Kenichiro Sakai ◽  
Yasuyuki Iguchi ◽  
Yasuhiro Nishiyama ◽  
...  

Cureus ◽  
2021 ◽  
Author(s):  
Mohammed Tahar Si Larbi ◽  
Waleed al Mangour ◽  
Iram Saba ◽  
Dhekra Al Naqeb ◽  
Zaina Swapna Faisal ◽  
...  

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