In Patients With Obsessive-compulsive Disorders and Major Depressive Disorders, Higher Anhedonia Scores Are Related to Low Self-efficacy

SummarySince the introduction of the monoamine oxydase inhibitors and the first tricyclic antidepressant (TCA) imipramine in the late fifties, the treatment of depressive disorders has been changed dramatically. Althought a great variety of antidepressants such as TCA's, selective serotoninte-re-uptake inhibitors (SSRI's) mianserin, trazodone, mirtazapine, moclobemide and venlafaxine has become available, the exact mode of action is not revealed as yet, and classification should be done according to the interference of antidepressants with central monoaminergic processes.As to the potential of causing interactions, special attention has to be given to the SSRI's because of their interference with the CYP450 isozyme system. Therapeutic monotoring is recommended for the TCA's. The choiseforan antidepressant should be based on various factors like symptomatology and severity of the depression, potential interactions and somatic and/or psychiatric comorbidity.Extensive clinical research has demonstrated that TCA's are the most effective for major depression with melancholia (vital depression) and depressive disorders in the elderly.

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Multicenter Double-blind Comparison of Sertraline and Desipramine for Concurrent Obsessive-Compulsive and Major Depressive Disorders

Archives of General Psychiatry ◽

10.1001/archpsyc.57.1.76 ◽

2000 ◽

Vol 57 (1) ◽

pp. 76 ◽

Cited By ~ 81

Author(s):

Rudolf Hoehn-Saric ◽

Philip Ninan ◽

Donald W. Black ◽

Stephen Stahl ◽

John H. Greist ◽

...

Keyword(s):

Depressive Disorders ◽

Obsessive Compulsive ◽

Major Depressive ◽

Double Blind ◽

Major Depressive Disorders ◽

Blind Comparison

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Peculiarities of Depressive Disorders in Emigrants and Re-Emigrants

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1806 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S491-S491

Author(s):

N.O. Maruta ◽

O.P. Venger ◽

T.V. Panko ◽

I.O. Yavdak

Keyword(s):

Mental Disorders ◽

Depressive Disorders ◽

Social Psychological ◽

Obsessive Compulsive ◽

Examination Method ◽

Personality Changes ◽

Competing Interest ◽

Depressive Syndromes ◽

Obsessive Compulsive Disorders ◽

Compulsive Disorders

IntroductionEmigration and remigration are one of the greatest modern problems and considered as a factor provoking manifestation and exacerbation of mental disorders as well as pathocharacterological personality changes. In emigrants and re-emigrants peculiarities of course of depressive disorders with different genesis are not investigated, that impedes a development of adequate therapeutic methods.AimTo study clinical-psychopathological peculiarities of depressive disorders in emigrants and re-emigrants patients with psychogenic (F43.21, F43.22) (69 non-emigrants, 68 emigrants, 67 re-emigrants), endogenous (F31.3, F31.4, F32.1, F32.2, F33.1, F33.2) (65, 66 and 63 patients, respectively) and organic depressive disorders (F06.3) (64, 62 and 61 patients, respectively) were examined.MethodsA clinical-psychopathological investigation, Standardized Personality Examination Method, Lusher's Method of Color Choices, HDRS, HARS, MADRS, and SCL-90-R.ResultsThe highest level of severity of depressive disorders in re-emigrants and the lowest level in non-emigrants were registered. Re-emigrants had predominantly depressive, asthenic-depressive and apathic-depressive forms, whereas emigrants had mainly anxious-depressive ones. According to SCL-90-R data, emigrants had higher indexes of somatization, obsessive-compulsive disorders, anxiety, whereas re-emigrants had higher indexes of depression and interpersonal sensitivity as well as an index of distress expression. In patients examined it was determined a predomination of dysthymic personality traits manifested in the frameworks of the leading depressive of anxious-depressive syndromes. An influence of emigration and remigration factors was the greatest in psychogenic depressions and the lowest in organic depressive disorders.ConclusionsThe abovementioned regularities should be taken into account in pharmacotherapy and a social-psychological support for such patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Common vulnerability factors in obsessive-compulsive and major depressive disorders: a transdiagnostic hierarchical model

Current Psychology ◽

10.1007/s12144-021-02599-2 ◽

2022 ◽

Author(s):

Servet Kaçar-Başaran ◽

Haluk Arkar

Keyword(s):

Hierarchical Model ◽

Depressive Disorders ◽

Vulnerability Factors ◽

Obsessive Compulsive ◽

Major Depressive ◽

Major Depressive Disorders

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Pathological gambling and comorbidities

European Psychiatry ◽

10.1016/s0924-9338(11)71803-x ◽

2011 ◽

Vol 26 (S2) ◽

pp. 92-92

Author(s):

H. Poppe ◽

B. Dillinger ◽

S. Lentner

Keyword(s):

Substance Abuse ◽

Pathological Gambling ◽

Personality Disorders ◽

Depressive Disorders ◽

Substance Dependence ◽

Underlying Disease ◽

Obsessive Compulsive ◽

Clinical Observations ◽

Obsessive Compulsive Disorders ◽

Compulsive Disorders

Pathological gambling accumulates frequently in connection with other diseases. This is documented both by studies and clinical observations, whereby no causalities can be derived, which underlying disease led to further diseases. Nevertheless different studies show similar results that pathological gambling arises increased in connection with substance dependence, depressive disorders, obsessive compulsive disorders and also personality disorders. These results stated in the literature also reflect the clinical observations of the Anton Proksch Institute.In the following presentation we will try to figure out the results of inpatients with the diagnosis pathological gambling, that were treated in the Anton Proksch Institute in the years 2008, 2009 and 2010. We find a range of comorbititys longing from substance abuse to personality disorders.

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