scholarly journals 10 / Comparison of Fresh Frozen Plasma (FFP) and Plasmalyte® for priming cardiopulmonary bypass in infants and children undergoing open-heart surgery: A double-blinded, randomised study.

Author(s):  
Audrey Dieu ◽  
Audrey ['Mona']
2003 ◽  
Vol 29 (10) ◽  
pp. 1736-1743 ◽  
Author(s):  
Stein Tølløfsrud ◽  
Harald Noddeland ◽  
Jan Ludvig Svennevig ◽  
Gunnar Bentsen ◽  
Tom Eirik Mollnes ◽  
...  

2016 ◽  
Vol 36 (3) ◽  
pp. 297-304
Author(s):  
Keiko OKAMURA ◽  
Junko ICHIKAWA ◽  
Mitsuharu KODAKA ◽  
Goro KANEKO ◽  
Mariko ONO ◽  
...  

2013 ◽  
Vol 25 (2) ◽  
pp. 158-159
Author(s):  
Nevin M. Habeeb ◽  
Adel Al Ansary ◽  
Nermeen Helmy ◽  
Omneya Ibrahim Youssef ◽  
Nadeen M. Habeeb

Perfusion ◽  
1994 ◽  
Vol 9 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Françoise Nicolas ◽  
Jean-Pierre Daniel ◽  
Jacqueline Bruniaux ◽  
Alain Serraf ◽  
François Lacour-Gayet ◽  
...  

There is still controversy about the optimal method of venoarterial cardiopulmonary bypass (CPB) for correction of congenital heart diseases in neonates and young infants. High rates of CPB-related morbidity and mortality are still reported. Since 1980, conventional CPB with double caval cannulation with right-angled cannulae has been used in the high majority of neonates at Marie-Lannelongue Hospital. The extracorporeal circuit was miniaturized to be primed with a volume as small as possible. Priming (500 ml) was done with packed red cells and fresh frozen plasma. CPB was conducted at 30% haematocrit and normal ranges of flow rate, arterial pressure, systemic vascular resistances and oxygen delivery. These normal physiological parameters were also maintained during hypothermia. During the last two years, 151 neonates below 15 days old who underwent open-heart surgery were reviewed. The overall hospital mortality was 7.24%. None of the survivors had postoperative complications related to CPB. All physiological and biological values remained within normal ranges during the postoperative course.


2003 ◽  
Vol 75 (5) ◽  
pp. 1506-1512 ◽  
Author(s):  
William C Oliver ◽  
Froukje M Beynen ◽  
Gregory A Nuttall ◽  
Darrell R Schroeder ◽  
Mark H Ereth ◽  
...  

Author(s):  
Eric N. Mendeloff ◽  
George F. Glenn ◽  
Paul Tavakolian ◽  
Eugene Lin ◽  
Allison Leonard ◽  
...  

Objective Thromboelastography (TEG) measures the dynamics of clot formation in whole blood and provides data that can guide specific blood component therapy. This study analyzed whether the implementation of TEG affected blood product utilization and overall hemostasis in infants (6 months and younger) undergoing open heart surgery. Methods TEG values measured include R (time to fibrin formation), angle (fibrinogen formation), and MA (platelet function). Blood product usage, TEG values, and operative parameters were collected during surgery on 112 consecutive infants (66 acyanotic) undergoing open heart surgery within the first 6 months of life. Controls consisted of chart data on 70 consecutive patients (57 acyanotic) undergoing the same surgical procedures before implementation of TEG (pre-TEG). Results Using TEG, the pattern of blood product utilization changed. Compared with the pre-TEG era, TEG era patients demonstrated a significant increase in fresh frozen plasma usage intraoperatively (4.74 vs. 1.83 mL/kg; P < 0.001) and reduced postoperative use of platelets (1.69 vs. 3.74 mL/kg; P = 0.006) and cryoprecipitate (0.89 vs. 1.95 mL/kg; P = 0.149). Chest tube drainage was significantly reduced at 1, 2, and 24 hours in the TEG group. TEG angle and MA measurements suggest that fibrinogen and platelets of cyanotic patients are more sensitive to hemodilution than the acyanotic patients. Conclusions TEG allows for proactive, goal-directed blood component therapy with improved postoperative hemostasis in infants undergoing cardiopulmonary bypass.


1988 ◽  
Vol 69 (2) ◽  
pp. 254-256 ◽  
Author(s):  
RAYMOND C. ROY ◽  
MICHAEL A. STAFFORD ◽  
ALLEN S. HUDSPETH ◽  
WAYNE MEREDITH

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