Genetic associations of serotoninergic and GABAergic genes in an extended collection of early-onset obsessive-compulsive disorder trios

2018 ◽  
Author(s):  
Ana Encarnacion Ortiz Garcia
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Genetic Associations ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Genetic Associations of Serotoninergic and GABAergic Genes in an Extended Collection of Early-Onset Obsessive-Compulsive Disorder Trios

2019 ◽  
Vol 29 (2) ◽  
pp. 152-157 ◽  
Author(s):  
Daniel Boloc ◽  
Sergi Mas ◽  
Natalia Rodriguez ◽  
Ana E. Ortiz ◽  
Astrid Morer ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Genetic Associations ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Genetics of early-onset obsessive–compulsive disorder

2010 ◽  
Vol 19 (3) ◽  
pp. 227-235 ◽  
Author(s):  
Susanne Walitza ◽  
Jens R. Wendland ◽  
Edna Gruenblatt ◽  
Andreas Warnke ◽  
Thomas A. Sontag ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Familial and sporadic subtypes of early-onset Obsessive-Compulsive disorder

2005 ◽  
Vol 57 (8) ◽  
pp. 895-900 ◽  
Author(s):  
Gregory L. Hanna ◽  
Daniel J. Fischer ◽  
Kristin R. Chadha ◽  
Joseph A. Himle ◽  
Michelle Van Etten
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Association Studies of Serotonin System Candidate Genes in Early-onset Obsessive-Compulsive Disorder

2007 ◽  
Vol 61 (3) ◽  
pp. 322-329 ◽  
Author(s):  
Diane E. Dickel ◽  
Jeremy Veenstra-VanderWeele ◽  
Nancy Chiu Bivens ◽  
Xiaolin Wu ◽  
Daniel J. Fischer ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Association Studies ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Serotonin System

Integrative Analysis of shared Genetic Pathogenesis by Autism Spectrum Disorder and Obsessive-Compulsive Disorder

2019 ◽  
Author(s):  
Dongbai Liu ◽  
Hongbao Cao ◽  
Kamil Can Kural ◽  
Qi Fang ◽  
Fuquan Zhang
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Large Scale ◽  
Genetic Network ◽  
Autism Spectrum ◽  
P Value ◽  
Genetic Associations ◽  
Obsessive Compulsive ◽  
Systematic Analysis ◽  
Gene Markers ◽  
Compulsive Disorder

Abstract Background Many common pathological features have been observed for both autism spectrum disorders (ASD) and obsessive-compulsive disorder (OCD). However, no systematic analysis of the common gene markers associated both ASD and OCD has been conducted so far. Results Here, two batches of large-scale literature based disease-gene relation data (updated in 2017 and 2019, respectively) and gene expression data were integrated to study the possible association between OCD and ASD at the genetic level. Genes linked to OCD and ASD present significant overlap (p-value<2.64e-39). A genetic network of over 20 genes was constructed, through which OCD and ASD may exert influence on each other. The 2017-based analysis suggested six potential common risk genes for OCD and ASD (CDH2, ADCY8, APOE, TSPO, TOR1A, and OLIG2), and the 2019-based study identified two more genes (DISP1 and SETD1A). Notably, the gene APOE identified by the 2017-based analysis has been implicated to have an association with ASD in a recently study (2018) with DNA methylation analysis. Conclusions Our results support the possible complex genetic associations between OCD and ASD. Genes linked to one disease is worthy of further investigation as potential risk factors for the other.

Early Onset of Response With Selective Serotonin Reuptake Inhibitors in Obsessive-Compulsive Disorder

2016 ◽  
Vol 77 (05) ◽  
pp. e605-e611 ◽  
Author(s):  
Yasmin Issari ◽  
Ewgeni Jakubovski ◽  
Christine A. Bartley ◽  
Christopher Pittenger ◽  
Michael H. Bloch
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Evidence for a Susceptibility Locus on Chromosome 10p15 in Early-Onset Obsessive-Compulsive Disorder

2007 ◽  
Vol 62 (8) ◽  
pp. 856-862 ◽  
Author(s):  
Gregory L. Hanna ◽  
Jeremy Veenstra-VanderWeele ◽  
Nancy J. Cox ◽  
Michelle Van Etten ◽  
Daniel J. Fischer ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Susceptibility Locus ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Chromosome 10P15

443. A controlled family study of early-onset obsessive-compulsive disorder

2000 ◽  
Vol 47 (8) ◽  
pp. S135-S136
Author(s):  
G.L. Hanna ◽  
G.C. Curtis ◽  
J.A. Himle ◽  
D.Q. Koram ◽  
K.R. Chadha ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Family Study ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Human-leukocyte antigen class II genes in early-onset obsessive-compulsive disorder

2017 ◽  
Vol 20 (5) ◽  
pp. 352-358 ◽  
Author(s):  
Natalia Rodriguez ◽  
Astrid Morer ◽  
E. Azucena González-Navarro ◽  
Patricia Gassó ◽  
Daniel Boloc ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Obsessive Compulsive Disorder ◽  
Early Onset ◽  
Human Leukocyte Antigen Class ◽  
Human Leukocyte ◽  
Class Ii ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Leukocyte Antigen
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