A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Binding Constants ◽  
Strong Fluorescence ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Hydrogel System

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Binding Constants ◽  
Strong Fluorescence ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Hydrogel System

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>

Fluorescent Probes for the Selective Detection of Cysteine in Water

2014 ◽  
Vol 605 ◽  
pp. 19-22
Author(s):  
Hae Jo Kim
Keyword(s):  
Fluorescent Probe ◽  
Michael Addition ◽  
In Vivo Imaging ◽  
Selective Detection ◽  
Strong Fluorescence ◽  
Turn On ◽  
Aqueous Solvent ◽  
Fluorescence Turn On ◽  
Hydroxybenzyl Alcohol

Two novel fluorescent chemodosimeters will be presented for the selective detection of cysteine over homocysteine and glutathione in aqueous solvent. First, a rhodamine-based fluorescent probe (1) will be reported. Masked with a para-hydroxybenzyl alcohol (HBA) unit, probe 1 initially showed a weak fluorescence but displayed a strong fluorescence through a series of reactions of Michael addition and intramolecular cyclization of cysteine, followed by deprotection of HBA. The caged probe (1) exhibited a selective and sensitive response toward cysteine over homocysteine and glutathione in HEPES buffer. Secondly, a fluorescein-based fluorescent probe will be discussed. A bromoacetyl functionalized fluorescein chemodosimeter (2) was utilized as a fluorescent probe for cysteine. The probe showed a selective and sensitive response to cysteine over homocysteine and glutathione in aqueous buffer through a rapid cyclization reaction. When cysteine was added, a fast fluorescence turn-on change of 2 was observed and applied to the in-vivo imaging of cysteine.

A novel boronic acid-based fluorescence turn on sensor for specific detection of adenosine in urine

2021 ◽  
pp. 109859
Author(s):  
Ran Wang ◽  
Dongxue Zhan ◽  
Guiqian Fang ◽  
Yan Ma ◽  
Peng Meng ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Specific Detection ◽  
Turn On ◽  
Fluorescence Turn On

scholarly journals A 7-Hydroxybenzoxazinone-Containing Fluorescence Turn-On Probe for Biothiols and Its Bioimaging Applications

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3102 ◽  
Author(s):  
Bin Li ◽  
Datong Zhang ◽  
Ruibing An ◽  
Yaling Zhu
Keyword(s):  
Amino Acids ◽  
Detection Limit ◽  
High Resistance ◽  
Hela Cells ◽  
Fluorescence Enhancement ◽  
Stokes Shift ◽  
Potential Utility ◽  
Strong Fluorescence ◽  
Turn On ◽  
Fluorescence Turn On

In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155 nm). Meanwhile, this probe exhibits high resistance to interference from other amino acids and competing species. PBD features good linearity ranges with a low detection limit of 14.5 nM for glutathione (GSH), 17.5 nM for cysteine (Cys), and 80.0 nM for homocysteine (Hcy), respectively. Finally, the potential utility of this probe for biothiol sensing in living HeLa cells is demonstrated.

A new peptide-based fluorescent probe selective for zinc(ii) and copper(ii)

2016 ◽  
Vol 4 (43) ◽  
pp. 6979-6988 ◽  
Author(s):  
Giuliana Donadio ◽  
Rita Di Martino ◽  
Rosario Oliva ◽  
Luigi Petraccone ◽  
Pompea Del Vecchio ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Turn On ◽  
Fluorescence Turn On

The designed peptide dH3w (dansyl-HPHGHW-NH2) showed a selective fluorescence turn-on response to Zn2+ and a turn-off response to Cu2+.

scholarly journals Cytidine-stabilized copper nanoclusters as a fluorescent probe for sensing of copper ions and hemin

RSC Advances ◽  
2018 ◽  
Vol 8 (17) ◽  
pp. 9057-9062 ◽  
Author(s):  
Yong Wang ◽  
Tianxia Chen ◽  
Zhengtao Zhang ◽  
Yongnian Ni
Keyword(s):  
Fluorescent Probe ◽  
Copper Ions ◽  
Simultaneous Detection ◽  
Inner Filter Effect ◽  
Copper Nanoclusters ◽  
Turn On ◽  
Filter Effect ◽  
Fluorescence Turn On

A sensitive and selective fluorescence “turn on–off” strategy for simultaneous detection of Cu2+and hemin was proposed on the basis of the formation of fluorescent CuNCs and the inner filter effect of hemin on the fluorescence of the CuNCs.

A highly selective fluorescence turn-on detection of ClO−with 1-methyl-1,2-dihydropyridine-2-thione unit modified tetraphenylethylene

2017 ◽  
Vol 53 (85) ◽  
pp. 11654-11657 ◽  
Author(s):  
Xiaobiao Dong ◽  
Guanxin Zhang ◽  
Jinbiao Shi ◽  
Yuancheng Wang ◽  
Ming Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Emission Feature ◽  
Aggregation Induced Emission ◽  
Turn On ◽  
Fluorescence Turn On

A novel fluorescent probe for ClO−is developed by the combination of a new ClO−responsive unit and the aggregation induced-emission feature of tetraphenylethylene.

scholarly journals Systematic oligoaniline-based derivatives: ACQ–AIE conversion with a tunable insertion effect and quantitative fluorescence “turn-on” detection of BSA

2019 ◽  
Vol 3 (2) ◽  
pp. 331-338 ◽  
Author(s):  
Hao Lu ◽  
Kun Wang ◽  
Beibei Liu ◽  
Meng Wang ◽  
Mingming Huang ◽  
...  
Keyword(s):  
Substituted Anilines ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Quantitative Fluorescence ◽  
Aniline Oligomer

Conversion from ACQ to AIE was achieved in aniline oligomer derivatives based on a novel “chain-insertion” pattern. The fully substituted anilines also showed a quantitative turn-on fluorescence response towards BSA.

A fluorogenic and red-shifted diphenyl phosphinate-based probe for selective peroxynitrite detection as demonstrated in fixed cells

2017 ◽  
Vol 41 (20) ◽  
pp. 11934-11940 ◽  
Author(s):  
Sandip V. Mulay ◽  
Youngsam Kim ◽  
Kyung Jin Lee ◽  
Tesla Yudhistira ◽  
Hee-Sung Park ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Response ◽  
Turn On

A new dicyanomethylene-4H-pyran-based fluorescent probe has been designed, synthesized and characterized. It shows selective “TURN-ON” fluorescence response upon reaction with ONOO−.

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