scholarly journals A 7-Hydroxybenzoxazinone-Containing Fluorescence Turn-On Probe for Biothiols and Its Bioimaging Applications

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3102 ◽  
Author(s):  
Bin Li ◽  
Datong Zhang ◽  
Ruibing An ◽  
Yaling Zhu
Keyword(s):  
Amino Acids ◽  
Detection Limit ◽  
High Resistance ◽  
Hela Cells ◽  
Fluorescence Enhancement ◽  
Stokes Shift ◽  
Potential Utility ◽  
Strong Fluorescence ◽  
Turn On ◽  
Fluorescence Turn On

In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155 nm). Meanwhile, this probe exhibits high resistance to interference from other amino acids and competing species. PBD features good linearity ranges with a low detection limit of 14.5 nM for glutathione (GSH), 17.5 nM for cysteine (Cys), and 80.0 nM for homocysteine (Hcy), respectively. Finally, the potential utility of this probe for biothiol sensing in living HeLa cells is demonstrated.

scholarly journals Coplanarity driven fluorescence turn-on sensor for chromium(iii) and its application for bio-imaging

2018 ◽  
Vol 17 (2) ◽  
pp. 239-244 ◽  
Author(s):  
G. Balamurugan ◽  
S. Velmathi
Keyword(s):  
Hela Cells ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Fluorescence Enhancement ◽  
Live Cell ◽  
Turn On ◽  
Bio Imaging ◽  
Heteroaromatic Aldehyde ◽  
Fluorescence Turn On

The sensing behaviour of benzimidazole and thiozole derivatives from heteroaromatic aldehyde was studied towards various cations and anions. S1 showed selectivity towards Cr3+ with fluorescence enhancement and live cell imaging of Hela cells was successfully demonstrated.

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Binding Constants ◽  
Strong Fluorescence ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Hydrogel System

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>

Thieno[3,2-c]pyran: an ESIPT based fluorescence “turn-on” molecular chemosensor with AIE properties for the selective recognition of Zn2+ ion

2020 ◽  
Vol 44 (28) ◽  
pp. 12019-12026 ◽  
Author(s):  
Divya Singhal ◽  
Ismail Althagafi ◽  
Ashish Kumar ◽  
Saroj Yadav ◽  
Ashok K. Prasad ◽  
...  
Keyword(s):  
Detection Limit ◽  
Selective Recognition ◽  
Turn On ◽  
Low Detection Limit ◽  
Fluorescence Turn On

Thieno[3,2-c]pyran was synthesized as a fluorescent turn-on chemosensor for the selective recognition of Zn2+ ions with a low detection limit (0.67 μM), and it also exhibited AIE properties.

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Binding Constants ◽  
Strong Fluorescence ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Hydrogel System

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>

A new mode to light up an adjacent DNA-scaffolded silver probe pair and its application for specific DNA detection

2014 ◽  
Vol 50 (100) ◽  
pp. 15991-15994 ◽  
Author(s):  
Bin-Cheng Yin ◽  
Jin-Liang Ma ◽  
Huynh-Nhu Le ◽  
Shilong Wang ◽  
Zengguang Xu ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Fluorescence Enhancement ◽  
Dna Detection ◽  
Probe Pair ◽  
Exonuclease Iii ◽  
Silver Nanocluster ◽  
Turn On ◽  
Fluorescence Turn On

By fluorescence enhancement of a proximity-dependent DNA-scaffolded silver nanocluster probe pair and exonuclease III-mediated signal amplification, we present a new fluorescence turn-on mode and its application for specific DNA detection.

Constructing a FRET-based molecular chemodosimeter for cysteine over homocysteine and glutathione by naphthalimide and phenazine derivatives

The Analyst ◽  
2015 ◽  
Vol 140 (1) ◽  
pp. 182-189 ◽  
Author(s):  
Lin Yang ◽  
Weisong Qu ◽  
Xiao Zhang ◽  
Yandi Hang ◽  
Jianli Hua
Keyword(s):  
Hela Cells ◽  
Fluorescence Enhancement ◽  
Turn On

A chemodosimeter PHSN achieved turn-on fluorescence enhancement at 540 nm and discrimination of cysteine from homocysteine and glutathione in Hela cells.

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