scholarly journals Pneumonectomy with carinal resection in patients with non-small cell lung cancer: short and long-term results

2018 ◽  
Vol 20 (4) ◽  
pp. 36-40
Author(s):  
I A Dadyev ◽  
M M Davydov ◽  
A G Abdullaev ◽  
I O Kulik ◽  
Z A Ambalova ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Treatment Outcomes ◽  
Term Treatment ◽  
Small Cell ◽  
Small Cell Lung ◽  
Resection Group ◽  
Carinal Resection ◽  
Long Term Treatment ◽  
Short And Long Term

Objective. With to compare short- and long-term treatment outcomes of different carinal resection techniques in patients with non-small cell lung cancer (NSCLC) and carina involvement. Materials and methods. We performed retrospective nonrandomized clinical trial with following groups of patients: patients underwent pneumonectomy with sleeve carinal resection (47 patients); patients underwent pneumonectomy with marginal and wedge carinal resection (18 patients). Statistical analysis was made using Statistic 6.0 program. Case-control analysis of the both groups was performed to evaluate short- and long-term treatment outcomes of different carinal resection techniques in patients with NSCLC and carina involvement. Results. Frequency of non-surgical and surgical complications was 27.7% and 18.5% correspondingly. Postoperative mortality was 8.5% in sleeve carinal resection group and 11.1% in marginal and wedge carinal resection group. Five-year survival rates were 32.6% in sleeve carinal resection group and 11.1% in marginal wedge carinal resection group.

scholarly journals Successful long-term treatment of non–small cell lung cancer positive for RET rearrangement with pemetrexed

2019 ◽  
Vol Volume 12 ◽  
pp. 5355-5358
Author(s):  
Masayuki Takeda ◽  
Kazuko Sakai ◽  
Kazuto Nishio ◽  
Kazuhiko Nakagawa
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Small Cell Lung ◽  
Long Term Treatment

Efficacy of platinum rechallenge chemotherapy in sensitive relapsed small cell lung cancer after a long-term treatment-free interval.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e18554-e18554
Author(s):  
Yasushi Murakami ◽  
Hideo Saka ◽  
Masahide Oki ◽  
Chiyoe Kitagawa ◽  
Yoshihito Kogure
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Small Cell Lung ◽  
Free Interval ◽  
Long Term Treatment

scholarly journals Clinical case of long-term pemetrexed-based chemotherapy treatment for pulmonary adenocarcinoma (ALA +)

2018 ◽  
pp. 68-72
Author(s):  
A. M. Lozhkina ◽  
M. A. Sviridenko ◽  
A. O. Cheremnykh ◽  
E. A. Filippova ◽  
M. A. Urtenova ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Clinical Case ◽  
Term Treatment ◽  
Small Cell ◽  
Chemotherapy Treatment ◽  
Small Cell Lung ◽  
First Line ◽  
Long Term Treatment ◽  
Alk Positive

The article describes a clinical case of ALK-positive non-small cell lung cancer and its long-term treatment with a chemotherapy drug pemetrexed as first-line regimen followed by pemetrexed maintenance therapy.

Tracheal sleeve pneumonectomy for non small cell lung cancer (NSCLC): Short and long-term results in a single institution

Lung Cancer ◽  
2008 ◽  
Vol 61 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Federico Rea ◽  
Giuseppe Marulli ◽  
Marco Schiavon ◽  
Andrea Zuin ◽  
Abdel-Mohsen Hamad ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Long Term Results ◽  
Small Cell Lung ◽  
Single Institution ◽  
Short And Long Term

scholarly journals Collaborative Care Management Associated With Improved Depression Outcomes in Patients With Personality Disorders, Compared to Usual Primary Care

2018 ◽  
Vol 9 ◽  
pp. 215013271877326 ◽  
Author(s):  
Jeremy J. Solberg ◽  
Mark E. Deyo-Svendsen ◽  
Kelsey R. Nylander ◽  
Elliot J. Bruhl ◽  
Dagoberto Heredia ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Clinical Outcomes ◽  
Collaborative Care ◽  
Care Management ◽  
Term Treatment ◽  
Study Cohort ◽  
Long Term Treatment ◽  
Patient Health ◽  
Short And Long Term

Background: The use of a collaborative care management (CCM) model can dramatically improve short- and long-term treatment outcomes for patients with major depressive disorder (MDD). Patients with comorbid personality disorder (PD) may experience poorer treatment outcomes for MDD. Our study seeks to examine the differences in MDD treatment outcomes for patients with comorbid PD when using a CCM approach rather than usual care (UC). Methods: In our retrospective cohort study, we reviewed the records of 9614 adult patients enrolled in our depression registry with the clinical diagnosis MDD and the diagnosis of PD (Yes/No). Clinical outcomes for depression were measured with Patient Health Questionnaire–9 (PHQ-9) scores at 6 months. Results: In our study cohort, 59.4% of patients (7.1% of which had comorbid PD) were treated with CCM, as compared with 40.6% (6.8% with PD) treated with UC. We found that the presence of a PD adversely affected clinical outcomes of remission within both groups, however, at 6 months patients with PD had significantly lower MDD remission rates when treated with UC as compared with those treated with CCM (11.5% vs 25.2%, P = .002). Patients with PD in the UC group were also noted to have an increased rate of persistent depressive symptoms (PHQ-9 score ≥10) at 6 months as compared with those in the CCM group (67.7% vs 51.7%, P = .004). Conclusions: In patients with comorbid MDD and PD, clinical outcomes at 6 months were significantly improved when treated with CCM compared with UC. This finding is encouraging and supports the idea that CCM is an effective model for caring for patients with behavioral concerns, and it may be of even greater benefit for those patients being treated for comorbid behavioral health conditions.

scholarly journals RESECTION OF TRACHEAL BIFURCATION IN TREATMENT OF NON-SMALL CELL LUNG CANCER (LITERATURE REVIEW)

2018 ◽  
Vol 17 (5) ◽  
pp. 94-105 ◽  
Author(s):  
I. A. Dadyev ◽  
М. M. Davydov ◽  
A. K. Chekini ◽  
M. A. Anisimov ◽  
S. S. Gerasimov ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Term Treatment ◽  
Small Cell ◽  
Anesthetic Techniques ◽  
Small Cell Lung ◽  
Extensive Experience ◽  
Long Term Treatment ◽  
Tracheal Bifurcation

Over the past few years, significant advances in surgical and anesthetic techniques as well as appropriate selection of patients have led to an improvement in the immediate and long-term treatment outcomes in patients with non-small cell lung cancer with involvement of tracheal bifurcation. In accordance with the current selection criteria, patients with contralateral lymph node metastases (lung root, aortic window, paratracheal area) require chemotherapy or chemoradiotherapy with subsequent estimation of follow-up and treatment strategy. Surgeries with resection of tracheobronchial bifurcation are considered technically complicated, and they should be performed in carefully selected lung cancer patients and only in specialized centers with extensive experience. It allows the incidence of intra-and postoperative complications to be significantly reduced.

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