Study of factors affecting mortality and morbidity in patients with peritonitis due to duodenal ulcer perforation at a tertiary center

Background: Peptic ulcer disease in the general population had lifetime prevalence of 5-10% with incidence of 0.1–0.3% per year. Despite the tremendous improvement in preventive therapies, the rate of complication of this disease is still high and is burdened by high morbidity and mortality. In present study, we aimed to study factors affecting mortality and morbidity in patients presenting with peritonitis due to duodenal ulcer perforation at our tertiary hospital. Material and Methods: Present study was single-center, prospective, observational study conducted in patients admitted, diagnosed with duodenal ulcer perforation and surgically treated at our hospital. Results: In present study period total 56 patients were studied. All were male, most common age group was 51-60 years (37.5%) followed by 41-50 years (23.21%). Duration from onset of symptoms to admission was >24 hours (30.36%) in most of patients followed by 12-24 hours (28.57%). Most commons symptoms were pain in abdomen (100%), vomiting (100%). Anaemia (37.5%), LRTI and Pulmonary complications (19.64%), Diabetes mellitus (12.5%) and Hypertension (10.71%) were common comorbidities noted. Associated risk factors were previous history of PUD (41.07%), Alcohol use (64.29%), Cigarette smoking (51.79%) and Use of NSAIDs (12.5%). Presence of free gas under diaphragm was noted in 83.93% patients. Intraoperatively duodenal perforation diameter was 1–5 mm (60.71%) in most of patients followed by 6–10 mm (23.21%). Only 1 patient had duodenal perforation diameter was > 20mm. Common postoperative complications were wound infection (37.5%) and pulmonary infection (21.43%). In present study mortality within 1 month was noted in 13 patients (23.21%). Most common factors related to mortality were delayed presentation > 24 hours (61.54%), age > 60 years (46.15%), diabetes mellites (38.46%), Size of perforation > 1 cm (38.46%) and septicaemic shock (23.08%). Conclusion: Delayed presentation > 24 hours, age > 60 years size of perforation > 1 cm were common factors related to mortality in duodenal ulcer perforation patients.

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A study on Factors Affecting Mortality and Morbidity in Patients Presenting with Peritonitis Due to Duodenal Ulcer Perforation

New Indian Journal of Surgery ◽

10.21088/nijs.0976.4747.10619.2 ◽

2019 ◽

Vol 10 (6) ◽

pp. 567-572

Author(s):

G Kishore Babu ◽

◽

Gowthami Penumur ◽

Keyword(s):

Duodenal Ulcer ◽

Mortality And Morbidity ◽

Factors Affecting ◽

Ulcer Perforation ◽

Duodenal Ulcer Perforation

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Omental Patch Repair for Duodenal Ulcer Perforation- Analysis of Factors Affecting Outcome: A Prospective Study

Journal of Gastroenterology Pancreatology & Liver Disorders ◽

10.15226/2374-815x/6/2/001125 ◽

2018 ◽

Vol 6 (2) ◽

pp. 1-6

Author(s):

Nitin Agarwal ◽

Arun Gupta ◽

BK Jain ◽

Ram Niwas Saran

Keyword(s):

Duodenal Ulcer ◽

Prospective Study ◽

Patch Repair ◽

Omental Patch ◽

Factors Affecting ◽

Ulcer Perforation ◽

A Prospective Study ◽

Duodenal Ulcer Perforation

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A clinical study of factors affecting the prognosis in duodenal ulcer perforation cases in tertiary care hospital, Kanchipuram district

International Surgery Journal ◽

10.18203/2349-2902.isj20195214 ◽

2019 ◽

Vol 6 (12) ◽

pp. 4290

Author(s):

Dhinesh Babu K. ◽

M. Bhaskar

Keyword(s):

Duodenal Ulcer ◽

Peptic Ulcer ◽

Tertiary Care ◽

Peptic Ulcer Perforation ◽

Care Hospital ◽

Chronic Alcoholic ◽

Factors Affecting ◽

Ulcer Disease ◽

Ulcer Perforation ◽

Duodenal Ulcer Perforation

Background: Peptic ulcer disease is an erosion of the lining of the stomach or duodenum. It is associated with potentially life-threatening complications such as bleeding, perforation and obstruction. The main predisposing factors for peptic ulcer perforation are smoking, use of non-steroidal anti-inflammatory drugs (NSAIDs), chronic stress, Helicobacter pylori infection, and age >60 years. In recent years, with introduction of proton pump inhibitors and increased knowledge of duodenal ulcer perforation (DUP) has decreased the incidence of DUP.Methods: 50 patients with DUP were studied prospectively with respect to age, gender, use of NSAIDs, morbidity, mortality and complications.Results: Out of 50 patients, the mean age of incidence DUP was 46 yrs, which is more common in males. And also 48% patients were chronic alcoholic and 52% patients were chronic smokers. Moreover, 14% patients were chronic NSAIDs users.Conclusions: Factors such as age, gender, use of NSAID, Alcohol and smoking affects the life expectancy of the patients, which leads to morbidity and mortality.

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