scholarly journals Autonomy, Choice and Treatment: Using Bourdieu's Theory of Practice to Explore Breast Cancer Patients' Preconceptions and Experiences of Public and Private Health Systems in New Zealand

2021 ◽  
Author(s):  
◽  
Kimberly Lyle Dobson

<p>This thesis analyses 11 breast cancer patients’ preconceptions and experiences of public and private health sectors in New Zealand. Previous studies exploring breast cancer have analysed a range of issues including race, socio-economic and age inequalities, issues occuring between the public and private sectors, and the communication strategies patients preferred with health providers. In contrast, this thesis uses concepts from Pierre Bourdieu’s theory of practice to explore breast cancer patients’ accounts of the public and private sectors and how these accounts are shaped. For many of the women interviewed, cultural and social capital played an important role in the negotiation of the health system, whether public or private. This is because both sectors, at times, provided little information about the disease, treatment, side effects, and entitlements. In these circumstances, social and cultural capital were valuable resources providing alternative health assistance. Participants’ preconceptions when relating their choice of public or private health systems showed clear positive associations with the private health sector. When discussing their experiences, the women that used the public sector showed a positive turnaround in their opinions related to the public sector. In comparison, the women that used the private sector maintained their views regardless of some negative issues being experienced. Despite their personal experiences, both public and private participants maintained positive associations with the private sector. The reliance many of the participants had on social and cultural capital in both the public and private health sectors raises questions regarding processes related to patient information, access to services, and about whether case management of cancer services might be appropriate. The contrasts between participants’ preconceptions of the public sector in comparison to experiences highlights the need for a public campaign celebrating the successes of public cancer services.</p>

2021 ◽  
Author(s):  
◽  
Kimberly Lyle Dobson

<p>This thesis analyses 11 breast cancer patients’ preconceptions and experiences of public and private health sectors in New Zealand. Previous studies exploring breast cancer have analysed a range of issues including race, socio-economic and age inequalities, issues occuring between the public and private sectors, and the communication strategies patients preferred with health providers. In contrast, this thesis uses concepts from Pierre Bourdieu’s theory of practice to explore breast cancer patients’ accounts of the public and private sectors and how these accounts are shaped. For many of the women interviewed, cultural and social capital played an important role in the negotiation of the health system, whether public or private. This is because both sectors, at times, provided little information about the disease, treatment, side effects, and entitlements. In these circumstances, social and cultural capital were valuable resources providing alternative health assistance. Participants’ preconceptions when relating their choice of public or private health systems showed clear positive associations with the private health sector. When discussing their experiences, the women that used the public sector showed a positive turnaround in their opinions related to the public sector. In comparison, the women that used the private sector maintained their views regardless of some negative issues being experienced. Despite their personal experiences, both public and private participants maintained positive associations with the private sector. The reliance many of the participants had on social and cultural capital in both the public and private health sectors raises questions regarding processes related to patient information, access to services, and about whether case management of cancer services might be appropriate. The contrasts between participants’ preconceptions of the public sector in comparison to experiences highlights the need for a public campaign celebrating the successes of public cancer services.</p>


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chih-Yang Wang ◽  
Yung-Chieh Chang ◽  
Yao-Lung Kuo ◽  
Kuo-Ting Lee ◽  
Pai-Sheng Chen ◽  
...  

Abstract Breast cancer is the most common cancer in women, and some patients develop recurrence after standard therapy. Effective predictors are urgently needed to detect recurrence earlier. The activation of Hedgehog signaling in breast cancer is correlated with poor prognosis. PTCH1 is an essential membrane receptor of Hedgehog. However, there are few reports about mutations in Hedgehog genes in breast cancer. We conducted a comprehensive study via an experimental and bioinformatics approach to detect mutated genes in breast cancer. Twenty-two breast cancer patients who developed recurrence within 24 months postoperatively were enrolled with 22 control cancer patients. Targeted deep sequencing was performed to assess the mutations among individuals with breast cancer using a panel of 143 cancer-associated genes. Bioinformatics and public databases were used to predict the protein functions of the mutated genes. Mutations were identified in 44 breast cancer specimens, and the most frequently mutated genes were BRCA2, APC, ATM, BRCA1, NF1, TET2, TSC1, TSC2, NOTCH1, MSH2, PTCH1, TP53, PIK3CA, FBXW7, and RB1. Mutation of these genes was correlated with protein phosphorylation and autophosphorylation, such as peptidyl-tyrosine and protein kinase C phosphorylation. Among these highly mutated genes, mutations of PTCH1 were associated with poor prognosis and increased recurrence of breast cancer, especially mutations in exons 22 and 23. The public sequencing data from the COSMIC database were exploited to predict the functions of the mutations. Our findings suggest that mutation of PTCH1 is correlated with early recurrence of breast cancer patients and will become a powerful predictor for recurrence of breast cancer.


2016 ◽  
Vol 17 (3) ◽  
pp. 1337-1340 ◽  
Author(s):  
Sara Khan ◽  
Naveed Ali Khan ◽  
Ata Ur Rehman ◽  
Iqra Khan ◽  
Khursheed A Samo ◽  
...  

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