EFFECT OF OBSTRUCTIVE SLEEP APNEA ON INCIDENCE OF PREECLAMPSY IN PREGNANT WOMEN: A SYSTEMATIC REVIEW

Author(s):  
Sulis Diana ◽  
◽  
Chatarina Umbul Wahyuni ◽  
Budi Prasetyo ◽  
◽  
...  
Author(s):  
Sulis Diana ◽  
◽  
Chatarina Umbul Wahyuni ◽  
Budi Prasetyo ◽  
◽  
...  

ABSTRACT Background: The prevalence of preeclampsia is around 5-8% of all diseases that occur during pregnancy. There was an increase from 10.5% of women with OSA in the first trimester to 26.7% in the third trimester. This study aimed to investigate the effect of obstructive sleep apnea on incidence of preeclampsia in pregnant women. Subjects and Method: A systematic review was conducted by searching the articles from PubMed and Google Scholar databases published between 2015 to 2019. An obstructive sleep apnoea (OSA) analysis was performed. Sensitivity analysis was performed to identify designs, summary results and publication estimates. Results: As many as 15 studies with a total of 1,837 subjects were included. OSA during pregnancy was associated with an increased risk of preeclampsia. The selected studies were conducted in observational designs. The existing studies showed that maternal OSA was significantly associated with preeclampsia (aOR= 1.96; 95% CI= 1.30 to 2.42). Conclusion: There is the adverse relationship of OSA and preeclampsia. OSA increases the risk of multiple pregnancy and perinatal complications. Keywords: preeclampsia, OSA, pregnancy Correspondence: Sulis Diana. Doctoral Program, Faculty of Public Health, Universitas Airlangga, Surabaya, East Java. Email: [email protected]. Mobile: +6282234209942. DOI: https://doi.org/10.26911/the7thicph.03.82


2019 ◽  
Vol 4 (5) ◽  
pp. 878-892
Author(s):  
Joseph A. Napoli ◽  
Linda D. Vallino

Purpose The 2 most commonly used operations to treat velopharyngeal inadequacy (VPI) are superiorly based pharyngeal flap and sphincter pharyngoplasty, both of which may result in hyponasal speech and airway obstruction. The purpose of this article is to (a) describe the bilateral buccal flap revision palatoplasty (BBFRP) as an alternative technique to manage VPI while minimizing these risks and (b) conduct a systematic review of the evidence of BBFRP on speech and other clinical outcomes. A report comparing the speech of a child with hypernasality before and after BBFRP is presented. Method A review of databases was conducted for studies of buccal flaps to treat VPI. Using the principles of a systematic review, the articles were read, and data were abstracted for study characteristics that were developed a priori. With respect to the case report, speech and instrumental data from a child with repaired cleft lip and palate and hypernasal speech were collected and analyzed before and after surgery. Results Eight articles were included in the analysis. The results were positive, and the evidence is in favor of BBFRP in improving velopharyngeal function, while minimizing the risk of hyponasal speech and obstructive sleep apnea. Before surgery, the child's speech was characterized by moderate hypernasality, and after surgery, it was judged to be within normal limits. Conclusion Based on clinical experience and results from the systematic review, there is sufficient evidence that the buccal flap is effective in improving resonance and minimizing obstructive sleep apnea. We recommend BBFRP as another approach in selected patients to manage VPI. Supplemental Material https://doi.org/10.23641/asha.9919352


Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1337-P
Author(s):  
SIRIMON REUTRAKUL ◽  
NARICHA CHIRAKALWASAN ◽  
SURANUT CHAROENSRI ◽  
SOMVANG AMNAKKITTIKUL ◽  
SUNEE SAETUNG ◽  
...  

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