scholarly journals Screening of viral markers for HIV HBV and HCV infections in blood donors in France and residual risk of viral transmission by blood transfusion

1998 ◽  
Vol 3 (7) ◽  
pp. 76-9 ◽  
Author(s):  
J Pillonel ◽  
C Saura ◽  
A M Couroucé

The first part of this article presents the results of screening tests for antibodies to human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and for hepatitis B surface antigen (HBsAg) from 1986 to 1996. The second part presents the most recent

2021 ◽  
Vol 8 (04) ◽  
pp. 199-203
Author(s):  
Jagjeewan Ram ◽  
Lubna Khan ◽  
Namrata Nigam ◽  
Aparna Singh

BACKGROUND Every blood transfusion is associated with 1 % chance of transfusion associated problems including transfusion transmitted blood-borne infections to its recipient. The major globally prevalent transfusion transmitted infections are human immunodeficiency virus, hepatitis B virus, hepatitis C virus, syphilis and malaria parasite. We wanted to compare safety of blood among replacement and voluntary donations by comparing the prevalence of transfusion-transmissible infections among them. METHODS All donors were screened by enzyme-linked immunoassay for five transfusion transmissible infectious agents - human immunodeficiency virus, hepatitis B virus, hepatitis C virus and syphilis by collecting plasma from the pilot tube attached to the blood bag. Malaria was tested from whole blood sample. RESULTS A total of 24,491 donors was included in the study. Among them 21,090 (86.11 %) were replacement and 3,401 (13.89 %) were voluntary donors. Out of 24,491 donors, 560 (2.29 %) units tested positive. Hepatitis B virus (hepatitis B surface antigen) is found to be the most prevalent transfusion transmitted infection among both replacement donations and voluntary donations. CONCLUSIONS There should be more voluntary donations to achieve safer blood transfusion practices as self-deferral by donors with high risk condition is the most effective way to reduce prevalence of transfusion transmitted infections. KEYWORDS Enzyme-Linked Immunoassay, Hepatitis C Virus, Hepatitis, Replacement Donors, Transfusion Transmitted Infections, Voluntary Donors


2016 ◽  
Vol 1 (3) ◽  
pp. 518-525 ◽  
Author(s):  
Md Zobaidul Alam ◽  
Md Amayan Hossain ◽  
Mahmud A Chowdhury

Human Immunodeficiency virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Syphilis infection are the major public health problem, alarming the most developing countries like Bangladesh. These studies determined the prevalence rate and risk factors of HIV, Hepatitis B, Hepatitis C and Syphilis among nonprofessional blood donors in multiple blood transfusion center of Chittagong. Information was collected by questionnaire to find out the relationship of HIV, HBV, HCV and Syphilis infection with age, sex, socioeconomic status, residence and religious believes. The sero-prevalence of HIV, HBsAg (HBV), anti-HCV (HCV), VDRL (Syphilis) among the non-professional blood donors were 00.00%, 4.88%, 0.92%, and 0.70% respectively. So, the highest prevalence rate was HBsAg and the lowest was HIV. We didn’t find more than one positive case in the same blood sample. The prevalence of HBsAg among the study population, students (120/6) were 5.00%, service holders (73/3) were 4.11%, businessmen (40/4) were 10%, housewives (14/0) were 00.00%, others (farmers, immigrant workers) (40/1) were 2.50%. The highest prevalence of HBsAg was due to illiteracy and unsafe sexual behaviors.Asian J. Med. Biol. Res. December 2015, 1(3): 518-525


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