scholarly journals Acute disorders of brain circulation and type 2 diabetes

2019 ◽  
pp. 57-60
Author(s):  
D. T. Khodjiyeva ◽  
D. К. Khaydarova ◽  
N. К. Khaydarov
Keyword(s):  
Type 2 Diabetes ◽  
Carbohydrate Metabolism ◽  
Cerebral Circulation ◽  
Clinical Course ◽  
The State ◽  
Brain Circulation

A study of the state of carbohydrate metabolism in patients with acute disorders of cerebral circulation (ADCC) was carried out.It is established that the development of a stroke is often preceded by a period of hyperglycemia. The level of glycosylatedhemoglobin affects the clinical course of a stroke, including the restoration of disturbed neurological functions. The debut ofdiabetes mellitus (DM) can coincide with the development of ADCC.

The state of carbohydrate metabolism and the development of cerebrovascular diseases in patients with type 2 diabetes mellitus

Pharmateca ◽  
2019 ◽  
Vol 4_2019 ◽  
pp. 61-67
Author(s):  
K.V. Antonova () Antonova ◽  
M.M. Tanashyan () Tanashyan ◽  
M.Yu. Maksimova () Maksimova ◽  
N.V. Shakhparonova () Shakhparonova ◽  
T.I. Romantsova () Romantsova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Carbohydrate Metabolism ◽  
Cerebrovascular Diseases ◽  
The State

scholarly journals Influence Of Different Hypoglycemic Therapy Schemes On Carbohydrate Exchange Indicators In Type 2 Diabetes Mellitus

2021 ◽  
Vol 03 (06) ◽  
pp. 13-19
Author(s):  
S.I. Ismailov ◽  
◽  
S.U. Muminova ◽  
Keyword(s):  
Type 2 Diabetes ◽  
Renal Function ◽  
Diabetic Nephropathy ◽  
Carbohydrate Metabolism ◽  
Impaired Renal Function ◽  
The State ◽  
Dipeptidyl Peptidase 4 ◽  
Number Of Patients ◽  
Group 1

Aim of the study: To study the effect of prescribing inhibitors of sodium glucose cotransporter type 2 (iSGLT-2) and inhibitors of dipeptidyl peptidase-4 (iDDP-4) on the parameters of carbohydrate metabolism in patients with type 2 diabetes. Materials and methods: A prospective study included 80 patients with type 2 diabetes. The average age was 52.7 ± 3.78 years; diabetes experience - 8 years; BMI-30 ± 0.17; Hb1C-9.2 ± 0.4%; fasting glycemia –10.2 mmol/; eGFR-78 ml/min; TG-2.7 ± 0.44; total cholesterol-3.4 ± 0.72; MAU 32 ± 0.125. The patients were divided into 2 groups: group 1 - 30 patients with DN with impaired renal function and 30 patients with diabetic nephropathy without renal dysfunction in the presence of metformin + iSGLT- 2; 2 group of 30 patients with impaired renal function and 30 patients with diabetic nephropathy without impaired renal function on the background of metformin + iDPP-4. Results: The study of the effect of the inclusion of drugs iSGLT-2 (group 1) and iDPP-4 (group 2) showed a positive dynamics of carbohydrate metabolism indicators in patients with type 2 diabetes. So if the initial indicators in the groups were comparable in terms of glycemic control indicators, then by the 3rd month of treatment there was a significant decrease in HbA1c in the 1st group of patients in relation to the 2nd group. The result of the correction performed within 3 months was the achievement of the state of compensation in the 1st group in 36.7%, and in the 2nd group in 28.3%, 48.3% of the patients of the 1st group were brought into the state of sub compensation and 31.7 % of patients of the 2nd group. Conclusion: On the combination of metformin and INGLT-2, a larger number of patients managed to achieve the set goals of therapy with a lower risk of overt hypoglycemia, then this combination should be considered not only more effective.

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