scholarly journals A BAYESIAN WEIBULL ANALYSIS OF BREAST CANCER DATA WITH LONG-TERM SURVIVORS IN PARANA STATE, BRAZIL

2021 ◽  
Vol 39 (2) ◽  
pp. 293-310
Author(s):  
Talita Evelin Nabarrete Tristão de MORAES ◽  
Isolde PREVIDELLI ◽  
Giovani Loiola da SILVA
Keyword(s):  
Breast Cancer ◽  
Survival Data ◽  
White Women ◽  
Age Groups ◽  
Population Based ◽  
Breast Cancer Data ◽  
Weibull Regression ◽  
Cancer Data ◽  
Long Term Survivors

Breast cancer is one of the most common diseases among women worldwide with about 25% of new cases each year. In Brazil, 59,700 new cases of breast cancer were expected in 2019, according to the Brazilian National Cancer Institute (INCA). Survival analysis has been an useful tool for the identifying the risk and prognostic factors for cancer patients. This work aims to characterize the prognostic value of demographic, clinical and pathological variables in relation to the survival time of 2,092 patients diagnosed with breast cancer in Parana State, Brazil, from 2004 to 2016. In this sense, we propose a Bayesian analysis of survival data with long-term survivors by using Weibull regression models through integrated nested Laplace approximations (INLA). The results point to a proportion of long-term survivors around 57:6% in the population under study. In regard to potential risk factors, we namely concluded that 40-50 year age group has superior survival than younger and older age groups, white women have higher breast cancer risk than other races, and marital status decreases that risk. Caution on the general use of these results is nevertheless advised, since we have analyzed population-based breast cancer data without proper monitoring by a healthprofessional.

scholarly journals LONG-TERM EFFECTS OF EPIRUBICIN ON INCIDENCE OF HEART FAILURE IN WOMEN WITH BREAST CANCER: DATA FROM A RANDOMIZED CLINICAL TRIAL

2016 ◽  
Vol 67 (13) ◽  
pp. 1513
Author(s):  
Ann Bøcher Secher Banke ◽  
Emil Fosbol ◽  
Jacob Møller ◽  
Gunnar Gislason ◽  
Mads Andersen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Heart Failure ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Breast Cancer Data ◽  
Long Term Effects ◽  
Cancer Data

scholarly journals Changes in self-reported sleep duration with age - a 36-year longitudinal study of Finnish adults

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Christer Hublin ◽  
Lassi Haasio ◽  
Jaakko Kaprio
Keyword(s):  
Sleep Duration ◽  
Age Groups ◽  
Population Based ◽  
Age Group ◽  
Weibull Regression ◽  
Adult Age ◽  
Study Population ◽  
Sleep Length

Abstract Background Sleep deprivation is often claimed to be increasingly common, but most studies show small changes in sleep duration over the last decades. Our aim was to analyze long-term patterns in self-reported sleep duration in a population-based cohort. Methods Members of the Older Finnish Twin Cohort have responded to questionnaires in 1975 (N = 30,915 individuals, response rate 89%, mean age 36 years), 1981 (24,535, 84%, 41 years), 1990 (12,450, 77%, 44 years), and 2011 (8334, 72%, 60 years). Weibull regression models were used to model the effects of follow-up time and age simultaneously. Results Sleep duration has decreased in all adult age groups and in both genders. The mean duration was in men 7.57 h in 1975 and 7.39 in 2011, and in women 7.69 and 7.37, respectively. The decrease was about 0.5 min in men and 0.9 in women per year of follow-up. In the age-group 18–34 years, mean sleep length was 7.69 h in 1975 and 7.53 in 1990. Among 35–54-year-old it was 7.57 h in 1975 and 7.34 in 2011, and in the age group of 55+ year olds 7.52 and 7.38, correspondingly. The change was largest in middle-aged group: about 23 min or about 0.6 min per year of follow-up. Conclusions There has been a slight decrease in mean sleep duration during the 36-year follow-up. Although the sleep duration was longer in 1970s and 1980s, the probable main cause for the change in this study population is the effect of aging.

Statistical Applications of Survival Data Analysis for Breast Cancer Data

2015 ◽  
Vol 4 (2) ◽  
pp. 30-36
Author(s):  
Ahammad Basha Shaik ◽  
◽  
Venkataramanaiah. M ◽  
Thasleema . ◽  
◽  
...  
Keyword(s):  
Breast Cancer ◽  
Data Analysis ◽  
Survival Data ◽  
Breast Cancer Data ◽  
Cancer Data

scholarly journals Changes In Self-Reported Sleep Duration With Age - A 36-Year Longitudinal Study of Finnish Adults

2020 ◽  
Author(s):  
Christer Hublin ◽  
Lassi Haasio ◽  
Jaakko Kaprio
Keyword(s):  
Sleep Duration ◽  
Regression Models ◽  
Age Groups ◽  
Population Based ◽  
Age Group ◽  
Weibull Regression ◽  
Adult Age ◽  
Sleep Length

Abstract Background: Sleep deprivation is often claimed to be increasingly common, but most studies show small changes in sleep duration over the last decades. Our aim was to analyze long-term patterns in self-reported sleep durationin a population-based cohort.Methods: Members ofthe Older Finnish Twin Cohort have responded to questionnaires in 1975 (N = 30,915 individuals,response rate 89%, mean age 36 years), 1981 (24,506, 84%, 41 years), 1990 (12,502,77%, 44 years), and 2011 (8510, 72%, 60 years).Weibull regression models were used to model the effects of follow-up time and age simultaneously.Results: Sleep duration has decreased in all adult age groups and in both genders.The mean duration was in men 7.57 hours in 1975 and 7.39 in 2011, and in women 7.69 and 7.37, respectively. The decrease was about 0.5minutes in men and 0.9in women per year of follow-up. In the age-group 18-34 years, mean sleep length was 7.69 hours in 1975 and 7.53 in 1990. Among 35-54-year-old it was 7.57 hours in 1975 and 7.34 in 2011, and in the age group of 55+ year olds7.52 and 7.38, correspondingly. The change was largest in middle-aged group: about 23 minutes or about 0.6 minutes per year of follow-up.Conclusions: There has been a slight decrease in mean sleep duration during the 36-year follow-up.Although the sleep duration was longer in 1970s and 1980s, the probablemain cause for the change in this study populationis the effect of aging.

scholarly journals Changes In Self-Reported Sleep Duration With Age - A 36-Year Longitudinal Study Of Finnish Adults

2020 ◽  
Author(s):  
Christer Hublin ◽  
Lassi Haasio ◽  
Jaakko Kaprio
Keyword(s):  
Sleep Duration ◽  
Age Groups ◽  
Population Based ◽  
Age Group ◽  
Weibull Regression ◽  
Adult Age ◽  
Study Population ◽  
Sleep Length

Abstract Background: Sleep deprivation is often claimed to be increasingly common, but most studies show small changes in sleep duration over the last decades. Our aim was to analyze long-term patterns in self-reported sleep duration in a population-based cohort. Methods: Members of the Older Finnish Twin Cohort have responded to questionnaires in 1975 (N = 30,915 individuals, response rate 89%, mean age 36 years), 1981 (24,506, 84%, 41 years), 1990 (12,502, 77%, 44 years), and 2011 (8510, 72%, 60 years). Weibull regression models were used to model the effects of follow-up time and age simultaneously. Results: Sleep duration has decreased in all adult age groups and in both genders. The mean duration was in men 7.57 hours in 1975 and 7.39 in 2011, and in women 7.69 and 7.37, respectively. The decrease was about 0.5 minutes in men and 0.9 in women per year of follow-up. In the age-group 18-34 years, mean sleep length was 7.69 hours in 1975 and 7.53 in 1990. Among 35-54-year-old it was 7.57 hours in 1975 and 7.34 in 2011, and in the age group of 55+ year olds 7.52 and 7.38, correspondingly. The change was largest in middle-aged group: about 23 minutes or about 0.6 minutes per year of follow-up. Conclusions: There has been a slight decrease in mean sleep duration during the 36-year follow-up. Although the sleep duration was longer in 1970s and 1980s, the probable main cause for the change in this study population is the effect of aging.

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