scholarly journals STUDY OF THE INNOVATIVE ANALGESIC DIAZAADAMANTANE DERIVATIVE CHRONIC EFFECT ON THE RENAL CONCENTRATION FUNCTION IN THE RAT

Author(s):  
Valentina Lavrinenko ◽  
Alina Fatianova
1981 ◽  
Vol 22 (3) ◽  
pp. 507-507
Author(s):  
Michiya Ohtaka ◽  
Masahiro Kihara ◽  
Yasuo Nara ◽  
Ryoichi Horie ◽  
Yukio Yamori

2018 ◽  
Vol 3 (5) ◽  
pp. 63-66
Author(s):  
S. A. Sherstyuk ◽  
◽  
S. A. Nakonechnaya ◽  
E. V. Nakonechnyi ◽  
Е. E. Koschiy ◽  
...  

Toxics ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 126
Author(s):  
June Wee ◽  
Yun-Sik Lee ◽  
Yongeun Kim ◽  
Jino Son ◽  
Kijong Cho

Glyphosate is the most used herbicide worldwide, but enormous use of glyphosate has raised concerned about its environmental loadings. Although glyphosate is considered non-toxic, toxicity data for soil non-target organisms according to temperature and aging are scarce. This study examined the toxicity of glyphosate with the temperature (20 °C and 25 °C) and aging times (0 day and 7 days) in soil using a collembolan species, Allonychiurus kimi (Lee). The degradation of glyphosate was investigated. Fatty acid composition of A. kimi was also investigated. The half-life of glyphosate was 2.38 days at 20 °C and 1.69 days at 25 °C. At 20 °C with 0 day of aging, the EC50 was estimated to be 93.5 mg kg−1. However, as the temperature and aging time increased, the glyphosate degradation increased, so no significant toxicity was observed on juvenile production. The proportions of the arachidonic acid and stearic acid decreased and increased with the glyphosate treatment, respectively, even at 37.1 mg kg−1, at which no significant effects on juvenile production were observed. Our results showed that the changes in the glyphosate toxicity with temperature and aging time were mostly dependent on the soil residual concentration. Furthermore, the changes in the fatty acid compositions suggest that glyphosate could have a chronic effect on soil organisms.


2016 ◽  
Vol 49 (3) ◽  
pp. 201-211 ◽  
Author(s):  
Plínio S. Furtado ◽  
Manuel A. J. Valenzuela ◽  
Gabriela Rodriguez-Fuentes ◽  
Bruno R. Campos ◽  
Wilson Wasielesky ◽  
...  
Keyword(s):  

2021 ◽  
Vol 50 (2) ◽  
pp. 42-46
Author(s):  
G. O. Kerkeshko

Experiments on chronic administration of melatonin with and without chronic inhalation of toluene dosed at both maximal permissible concentration (50 mg/ml) and limited chronical range (500 mg/m3) have been carried out on female rats to discover their effects on biogenic amines system in hypothalamic structures related to gonadoliberin synthesis and secretion - preoptic area (PA) and median eminence (ME). Contents of biogenic amines in ME and especially in PA have been shown to have circadian variations with maximum in the morning in control group of rats.The chronic effect of synchronizing agent melatonin (administered dissolved in drinking water in concentration of 10 pg/m l, at night during 2 months) on neotransmitters and their circadian variations in both hypothalamic structures proved surprisingly to be much alike the effect of toluene. Both chemicals cause the disturbances of normal circadian variations o f norepinephrine, dopamine and serotonine in PA and dopamine in ME. The simultaneous administration of toluene and melatonin showed likewise no synchronizing ability of the latter under the conditions described.


1999 ◽  
Vol 36 (01) ◽  
pp. 139-145 ◽  
Author(s):  
Owen Dafydd Jones

Conditions are derived for the components of the normed limit of a multi-type branching process with varying environments, to be continuous on (0, ∞). The main tool is an inequality for the concentration function of sums of independent random variables, due originally to Petrov. Using this, we show that if there is a discontinuity present, then a particular linear combination of the population types must converge to a non-random constant (Equation (1)). Ensuring this can not happen provides the desired continuity conditions.


1999 ◽  
Vol 32 (12) ◽  
pp. 1561-1564 ◽  
Author(s):  
M.C. Oliveira ◽  
H.P. Messinger ◽  
M. Tannhauser ◽  
L. Barbosa-Coutinho
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