CHANGES IN THE QUANTITATIVE COMPOSITION OF NEUROGLIA IN THE PREFRONTAL CORTEX OF RATS WITH MODELED POST-TRAUMATIC STRESS DISORDER

2019 ◽  
Vol 17 (6) ◽  
Author(s):  
G.M. Khayrullina ◽  
I.A. Vacoliuk
Keyword(s):  
Prefrontal Cortex ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Quantitative Composition ◽  
Post Traumatic Stress ◽  
Post Traumatic

Prefrontal cortex rTMS reverses behavioral impairments and differentially activates c-Fos in a mouse model of post-traumatic stress disorder

2019 ◽  
Vol 12 (1) ◽  
pp. 87-95 ◽  
Author(s):  
Marc Legrand ◽  
Romain Troubat ◽  
Bruno Brizard ◽  
Anne-Marie Le Guisquet ◽  
Catherine Belzung ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Mouse Model ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
Behavioral Impairments

scholarly journals Diminished medial prefrontal cortex activation during the recollection of stressful events is an acquired characteristic of PTSD

2017 ◽  
Vol 48 (7) ◽  
pp. 1128-1138 ◽  
Author(s):  
M. K. Dahlgren ◽  
L. M. Laifer ◽  
M. B. VanElzakker ◽  
R. Offringa ◽  
K. C. Hughes ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Twin Studies ◽  
Stressful Events ◽  
Functional Magnetic Resonance ◽  
Post Traumatic Stress ◽  
Post Traumatic

AbstractBackgroundPrevious research has shown relatively diminished medial prefrontal cortex activation and heightened psychophysiological responses during the recollection of personal events in post-traumatic stress disorder (PTSD), but the origin of these abnormalities is unknown. Twin studies provide the opportunity to determine whether such abnormalities reflect familial vulnerabilities, result from trauma exposure, or are acquired characteristics of PTSD.MethodsIn this case–control twin study, 26 male identical twin pairs (12 PTSD; 14 non-PTSD) discordant for PTSD and combat exposure recalled and imagined trauma-unrelated stressful and neutral life events using a standard script-driven imagery paradigm during functional magnetic resonance imaging and concurrent skin conductance measurement.ResultsDiminished activation in the medial prefrontal cortex during Stressful v. Neutral script-driven imagery was observed in the individuals with PTSD, relative to other groups.ConclusionsDiminished medial prefrontal cortex activation during Stressful v. Neutral script-driven imagery may be an acquired characteristic of PTSD. If replicated, this finding could be used prospectively to inform diagnosis and the assessment of treatment response.

Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder

2014 ◽  
Vol 268 ◽  
pp. 72-80 ◽  
Author(s):  
C. Brad Wilson ◽  
Leslie D. McLaughlin ◽  
Philip J. Ebenezer ◽  
Anand R. Nair ◽  
Joseph Francis
Keyword(s):  
Valproic Acid ◽  
Animal Model ◽  
Prefrontal Cortex ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Post Traumatic
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