Quality of life of people living with HIV/AIDS and on highly active antiretroviral therapy in Ethiopia

2010 ◽  
Vol 9 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Kebede Abera ◽  
Teferi Gedif ◽  
Ephrem Engidawork ◽  
Tsige Gebre-Mariam
2018 ◽  
Vol 4 (1) ◽  
pp. 43-52
Author(s):  
David Ufuoma Adje ◽  
Felicia Esemekiphorar Williams ◽  
Chukwuka Nicholas Bezugbe ◽  
Dauda Audi Dangiwa

Background:       Adherence to Highly Active Antiretroviral Therapy (HAART) is critical in achieving treatment goals, avoiding antimicrobial resistance, preventing treatment failure and improving the patient’s quality of life. Objectives: To assess the knowledge of antiretroviral therapy (ART) and adherence to antiretroviral (ARVs) medicines amongst People Living With HIV/AIDS (PLWHA) accessing care in two Nigerian Military HIV/AIDS Treatment sites. Methods: Four hundred patients on HAART who visited the study sites during the study period were recruited for the study using systematic random sampling method. A semi-structured, pretested, interviewer-administered questionnaire was used to obtain demographic details. Patients’ knowledge of HIV was assessed using an 8-item questionnaire while adherence was measured using the Simplified Medication Adherence Questionnaire (SMAQ). Results: The predominant age group was 31-40 years (46.4%). There were more females (69%) than males (31%). Only 45.5% answered knowledge questions correctly. The adherence level in this study was 64.0%. The major reasons cited for non-adherence included being away from home (23.6%), forgetfulness (17.1%), busy schedule (14%), need to conceal medication (12.7%) and feeling better (11.6%). Conclusion: Patients’ knowledge of ART and adherence to ARVs medicines were sub-optimal. Appropriate strategies to improve patients’ knowledge of ART and adherence to ARVs are recommended.


2020 ◽  
Author(s):  
Abreha Addis Gesese ◽  
Yitages Getachew Desta ◽  
Endale zenebe Behire

Abstract Background: Despite of the availability of Highly Active Antiretroviral Therapy, people living with HIV/AIDS suffer from socioeconomic, behavioral and psychosocial related factors affecting their quality of life. Previous studies assessed the magnitude of quality of life but the present one will identify behavioral and psychosocial factors associated with poor quality of live among adult PLWHIV on Antiretroviral therapy in the study setting.Objective: To identify behavioral and psychosocial determinants of Quality of life among Adult PLWHIV on HARRT, in Public Hospitals of Jimma Zone, South West, Ethiopia 2018.Method: Institution based unmatched case control study was employed. Simple random sampling technique was used to select cases and controls using screening criteria. Interviewer administered data collection method was used. Data were entered into Epi-Data and analyzed using SPSS version 20. Bivariate and multivariate logistic regressions were performed. The study was conducted from March 10-April 10- 2018.Results: A total of 75(25%) cases and 225(75%) of controls included in the study. Finally, the odds of poor quality of life among underweight (BMI kg/m2) 2.7 times [AOR 2.7 95%CI (1.0, 7.1)] more likely than normal /obese respondents, khat chewing 1-4 times/weak/month about 4.5 times [AOR 4.5 95%CI (1.85, 10.9)] and at daily intervals 4.7 times more [AOR 4.7 95% CI (1.18, 18.8)] likely than who never chew respectively. Being dissatisfied from support AOR 9.8 95% CI (1.9, 50), Stigmatized patients 8 times more likely than non-stigmatized AOR 8.0 95%CI (3.6, 18.1). Moreover, the odds of poor quality of life among severely depressed patients were 4 times AOR 4.0 95% CI (1.67, 9.83) more likely than mild depressed patients.Conclusion: Being underweight (BMI kg/m2), khat chewing 1-4 times/weak/month, khat chewing at daily interval, being dissatisfied from support, stigma and depression were independently associated. This may inform possible interventions to reduce comorbidities and disease exacerbation by improving on dietary and nutritional programs and support, reducing behavioral factors, improving social support, reducing stigma and depression by appropriate counseling and strengthening currently existing Information Education Communication to help develop life skills.


2020 ◽  
Author(s):  
Abreha Addis Gesese ◽  
Yitages Getachew Desta ◽  
Endale zenebe Behire

Abstract Background: Despite of the availability of Highly Active Antiretroviral Therapy, people living with HIV/AIDS suffer from socioeconomic, behavioral and psychosocial related factors affecting their quality of life. Previous studies assessed the magnitude of quality of life but the present one will identify behavioral and psychosocial factors associated with poor quality of live among adult PLWHIV on Antiretroviral therapy in the study setting.Objective: To identify behavioral and psychosocial determinants of Quality of life among Adult PLWHIV on HARRT, in Public Hospitals of Jimma Zone, South West, Ethiopia 2018.Method: Institution based unmatched case control study was employed. Simple random sampling technique was used to select cases and controls using screening criteria. Interviewer administered data collection method was used. Data were entered into Epi-Data and analyzed using SPSS version 20. Bivariate and multivariate logistic regressions were performed. The study was conducted from March 10-April 10- 2018.Results: A total of 75(25%) cases and 225(75%) of controls included in the study. Finally, the odds of poor quality of life among underweight (BMI kg/m2) 2.7 times [AOR 2.7 95%CI (1.0, 7.1)] more likely than normal /obese respondents, khat chewing 1-4 times/weak/month about 4.5 times [AOR 4.5 95%CI (1.85, 10.9)] and at daily intervals 4.7 times more [AOR 4.7 95% CI (1.18, 18.8)] likely than who never chew respectively. Being dissatisfied from support AOR 9.8 95% CI (1.9, 50), Stigmatized patients 8 times more likely than non-stigmatized AOR 8.0 95%CI (3.6, 18.1). Moreover, the odds of poor quality of life among severely depressed patients were 4 times AOR 4.0 95% CI (1.67, 9.83) more likely than mild depressed patients.Conclusion: Being underweight (BMI kg/m2), khat chewing 1-4 times/weak/month, khat chewing at daily interval, being dissatisfied from support, stigma and depression were independently associated. This may inform possible interventions to reduce comorbidities and disease exacerbation by improving on dietary and nutritional programs and support, reducing behavioral factors, improving social support, reducing stigma and depression by appropriate counseling and strengthening currently existing Information Education Communication to help develop life skills.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Amanuel Tesfay ◽  
Abebe Gebremariam ◽  
Mulusew Gerbaba ◽  
Hailay Abrha

Background. Health related quality of life (HRQOL) is an important outcome measure for highly active antiretroviral treatment program. In Ethiopia, studies revealed that there are improved qualities of life among adults living with the viruses taking antiretroviral therapy but there is no explicit data showing gender differences in health related quality of life.Aim. To assess gender differences in HRQOL and its associated factors among people living with HIV and on highly active antiretroviral therapy in public health institutions of Mekelle town, Northern Ethiopia.Methods. A comparative cross-sectional study was conducted among 494 adult people living with HIV taking ART services. Quality of life was measured using WHOQOL-HIV BREF.Result. There was a statistically significant gender difference (P<0.05) in HRQOL among PLHIV on HAART. Females had low score in all HRQOL domains. High perceived stigma was strongly associated with poor psychological quality of domain among both female and male groups with[AOR=2.89(1.69,4.96)]and[AOR=2.5(1.4,4.4)], respectively.Conclusion. There was statistically significant gender difference in all quality of life domains. Public health interventions to improve HRQOL of PLHIV should take in to account the physical, psychological, social, environmental, and spiritual health of PLHIV during treatment, care, and support.


2018 ◽  
Vol 49 (3) ◽  
pp. 20-29
Author(s):  
George Mamboleo ◽  
George T. Mugoya ◽  
Jonathan Nauser ◽  
Adrionia Molder ◽  
Fais Connor ◽  
...  

The development of highly active antiretroviral therapy (HAART) has shifted human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) from an acute to a chronic condition. Due to reduced fatality, approximately 1.1 million people living with HIV/AIDS (PLWHA) are faced with increased longevity in conjunction with functional consequences associated with chronic disability. Employment has been associated with increased treatment adherence, quality of life (QoL), and mental and physical health for people living with HIV/AIDS. The purpose of this study was to determine the relationship between employment status and QoL for PLWHA. Participants included 115 patients receiving services from two Ryan White HIV/AIDS Program (RWHAP) clinics in a rural Mid Atlantic Appalachian region of the U.S. Findings revealed statistically significant differences in employment status on six domains of the World Health Organization’s Quality of Life scale for PLWHA (WHOQOL-HIV-Bref), except for spirituality/religion/personal beliefs. Implications for practice and research are discussed.


2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Angga Wilandika

ABSTRAKHIV/AIDS merupakan salah satu penyakit yang dapat menyebabkan kematian pada penderitanya. Penyakit ini mengganggu kualitas hidup penderitanya. Terlebih lagi sampai saat ini penyakit HIV/AIDS belum ada obatnya. Meskipun demikian, penyakit HIV/AIDS dapat dikendalikan dengan penggunaan terapi antiretroviral. Saat ini terapi antiretroviral sudah banyak dikembangkan dan golongan terbaru yang dianggap cukup efektif mengendalikan gelaja HIV/AIDS yaitu Highly Active Anti-Retroviral Therapy (HAART). Artikel ini bertujuan untuk mengidentifikasi penggunaan HAART terhdap health related quality of life (HRQOL) atau kualitas hidup kesehatan dari orang dengan HIV/AIDS (ODHA). Penelusuran literatur dilakukan melalui database PubMed dan ProQuest Nursing and Allied Health Source (Januari 2005 – Oktober 2017), menggunakan kata kunci penelusuran “quality of life”, “helath related quality of life”, “HAART”, dan HIV/AIDS. Selain itu, artikel yang dipilih dibatasi hanya pada penelitian original. Hasil kajian mengungkapkan bahwa penggunaan HAART pada ODHA dapat menekan jumlah virus HIV yang berdampak meningkatkan kadar CD4 dalam tubuh. Penggunaan HAART dapat meningkatkan sistem kekebalan tubuh ODHA, sehingga usia penderita HIV/AIDS cenderung memanjang dan kualitas hidup pun menjadi lebih baik. Namun di sisi lain, penggunaan HAART yang dikonsumsi ODHA seumur hidup juga memiliki efek samping terkait toksisitas obat tersebut. Ada kalanya beberapa ODHA mengalami komplikasi dari penggunaan obat HAART tersebut. Oleh karena itu penggunaan obat HAART sebaiknya dilakukan secara teratur dengan pengawasan tim medis atau perawat yang kompeten dalam pemberian terapi antiretroviral.ABSTRACTHIV/AIDS is one disease that cause death. This disease can reduce the quality of life of peple living with HIV/AIDS (PLWHA). There is no cure for HIV/AIDS, until now. However, HIV/AIDS is a deadly disease and incureable, but this disease can be controlled with the use of antiretroviral therapy. Currently, antiretroviral therapy has been widely developed and the latest class was considered quite effective in controlling the HIV/AIDS is Highly Active Anti-Retroviral Therapy (HAART). This article aims to identify the use of HAART on health related quality of life (HRQOL) or the quality of life of PLWHA. The methode used was the literature review. The literature search was conducted through the PubMed and ProQuest Nursing and Allied Health Source (January 2005 – October 2017) databases, were searched using keyword  term "quality of life", "health related quality of life", "HAART" and “HIV/AIDS”. In addition, the selected article is limited only to original research. The study results revealed that the use of HAART in people living with HIV/AIDS could reduce the viral load, so that can increase the levels of CD4 in the body. HAART could improve the immune system of PLWHA, so the age of PLWHA tend to elongate and the quality of life can be better. However, the use of HAART also has side effects related to the toxicity of the drug. Some PLWHA experience complications from the use of HAART drugs. Therefore, the use of HAART drugs should be carried out regularly with the supervision of a medical team or nurse who is competent in the administration of antiretroviral drugs.


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