scholarly journals Penggunaan Highly Active Antiretroviral Theraphy (HAART) Terhadap Health Related Quality of Life (HRQOL) pada Orang Dengan HIV/AIDS

2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Angga Wilandika

ABSTRAKHIV/AIDS merupakan salah satu penyakit yang dapat menyebabkan kematian pada penderitanya. Penyakit ini mengganggu kualitas hidup penderitanya. Terlebih lagi sampai saat ini penyakit HIV/AIDS belum ada obatnya. Meskipun demikian, penyakit HIV/AIDS dapat dikendalikan dengan penggunaan terapi antiretroviral. Saat ini terapi antiretroviral sudah banyak dikembangkan dan golongan terbaru yang dianggap cukup efektif mengendalikan gelaja HIV/AIDS yaitu Highly Active Anti-Retroviral Therapy (HAART). Artikel ini bertujuan untuk mengidentifikasi penggunaan HAART terhdap health related quality of life (HRQOL) atau kualitas hidup kesehatan dari orang dengan HIV/AIDS (ODHA). Penelusuran literatur dilakukan melalui database PubMed dan ProQuest Nursing and Allied Health Source (Januari 2005 – Oktober 2017), menggunakan kata kunci penelusuran “quality of life”, “helath related quality of life”, “HAART”, dan HIV/AIDS. Selain itu, artikel yang dipilih dibatasi hanya pada penelitian original. Hasil kajian mengungkapkan bahwa penggunaan HAART pada ODHA dapat menekan jumlah virus HIV yang berdampak meningkatkan kadar CD4 dalam tubuh. Penggunaan HAART dapat meningkatkan sistem kekebalan tubuh ODHA, sehingga usia penderita HIV/AIDS cenderung memanjang dan kualitas hidup pun menjadi lebih baik. Namun di sisi lain, penggunaan HAART yang dikonsumsi ODHA seumur hidup juga memiliki efek samping terkait toksisitas obat tersebut. Ada kalanya beberapa ODHA mengalami komplikasi dari penggunaan obat HAART tersebut. Oleh karena itu penggunaan obat HAART sebaiknya dilakukan secara teratur dengan pengawasan tim medis atau perawat yang kompeten dalam pemberian terapi antiretroviral.ABSTRACTHIV/AIDS is one disease that cause death. This disease can reduce the quality of life of peple living with HIV/AIDS (PLWHA). There is no cure for HIV/AIDS, until now. However, HIV/AIDS is a deadly disease and incureable, but this disease can be controlled with the use of antiretroviral therapy. Currently, antiretroviral therapy has been widely developed and the latest class was considered quite effective in controlling the HIV/AIDS is Highly Active Anti-Retroviral Therapy (HAART). This article aims to identify the use of HAART on health related quality of life (HRQOL) or the quality of life of PLWHA. The methode used was the literature review. The literature search was conducted through the PubMed and ProQuest Nursing and Allied Health Source (January 2005 – October 2017) databases, were searched using keyword  term "quality of life", "health related quality of life", "HAART" and “HIV/AIDS”. In addition, the selected article is limited only to original research. The study results revealed that the use of HAART in people living with HIV/AIDS could reduce the viral load, so that can increase the levels of CD4 in the body. HAART could improve the immune system of PLWHA, so the age of PLWHA tend to elongate and the quality of life can be better. However, the use of HAART also has side effects related to the toxicity of the drug. Some PLWHA experience complications from the use of HAART drugs. Therefore, the use of HAART drugs should be carried out regularly with the supervision of a medical team or nurse who is competent in the administration of antiretroviral drugs.

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Amanuel Tesfay ◽  
Abebe Gebremariam ◽  
Mulusew Gerbaba ◽  
Hailay Abrha

Background. Health related quality of life (HRQOL) is an important outcome measure for highly active antiretroviral treatment program. In Ethiopia, studies revealed that there are improved qualities of life among adults living with the viruses taking antiretroviral therapy but there is no explicit data showing gender differences in health related quality of life.Aim. To assess gender differences in HRQOL and its associated factors among people living with HIV and on highly active antiretroviral therapy in public health institutions of Mekelle town, Northern Ethiopia.Methods. A comparative cross-sectional study was conducted among 494 adult people living with HIV taking ART services. Quality of life was measured using WHOQOL-HIV BREF.Result. There was a statistically significant gender difference (P<0.05) in HRQOL among PLHIV on HAART. Females had low score in all HRQOL domains. High perceived stigma was strongly associated with poor psychological quality of domain among both female and male groups with[AOR=2.89(1.69,4.96)]and[AOR=2.5(1.4,4.4)], respectively.Conclusion. There was statistically significant gender difference in all quality of life domains. Public health interventions to improve HRQOL of PLHIV should take in to account the physical, psychological, social, environmental, and spiritual health of PLHIV during treatment, care, and support.


Author(s):  
S. Cynthia Subhaprada ◽  
Shasank R. V. S. S. ◽  
T. Sivakala ◽  
S. Madhusai

Background: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. Combined with ART, Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). The objective of this study is to assess health related quality of life of HIV/AIDS patients attending ART clinic Tertiary care hospital, GGH, Kurnool and to determine the association of socio-demographic and disease related variables with health related quality of life.Methods: A cross-sectional study was conducted from April 2019 to June 2019 involving 400 purposively selected HIV-positive patients of age >18 years, who were taking highly active anti-retroviral therapy for the past 6months from the ART center, GGH, Kurnool. After obtaining IEC clearance and informed consent, WHOQOL-BREF instrument was used for data collection. Data analysis was performed using IBM SPSS version 26.0.Results: Out of the 400 participants, 60% were males. The mean age of the participants was 38.5±10.54 years. Overall quality of life had a mean score of 69.71. Physical (82.57) and level of independence (78.78) domains showed higher mean score when compared to psychological (63.82), environmental (61.49) and Social (60.26) domains.Conclusions: Among study subjects 15.5% had excellent QoL (≥80), nearly 69.75% had good QoL (60-79) and 14.75% had poor QoL (<60). Low QoL scores were seen in the social domain, suggesting that more social interventions are required in this population.


2016 ◽  
Vol 21 (6) ◽  
pp. 1580-1587 ◽  
Author(s):  
Mary M. Mitchell ◽  
Trang Q. Nguyen ◽  
Sarina R. Isenberg ◽  
Allysha C. Maragh-Bass ◽  
Jeanne Keruly ◽  
...  

2011 ◽  
Vol 8 (1) ◽  
pp. 5 ◽  
Author(s):  
Allyson Ion ◽  
Wenjie Cai ◽  
Dawn Elston ◽  
Eleanor Pullenayegum ◽  
Fiona Smaill ◽  
...  

2020 ◽  
Author(s):  
Fikadu Tadesse Nigusso ◽  
Azwihangwisi Helen Mavhandu-Mudzusi

Abstract Background: Health-related quality of life (HRQoL) serves as a direct measure of individuals’ health, life expectancy and the impact that the utilization of health care has on quality of life. The purpose of this study is to assess the HRQoL of people living with HIV/AIDS (PLWHA), and to ascertain its association with the social inequalities and clinical determinants among people living with HIV in Benishangul Gumuz Regional State, Ethiopia.Methods: A cross-sectional study was conducted between December 2016 and February 2017; 390 people at two referral hospitals and three health centers participated in the study. The Patient-Reported Outcomes Measurement Information System Global Health Scale (PROMIS Global 10) was used to measure key HRQoL domains. Physical Health Summary (PHS) and Mental Health Summary (MHS) scores were employed. PHS and MHS scores below 50 (the standardized mean score) were determined to be poor and above 50 to be good. Bivariate and multivariate logistic regression analyses were used to identify factors associated with PHS and MHS scores. Results: This study included 259 (66.4%) females and 131 (33.6%) males. The PHS scores ranged from 16.2 to 67.7 with a mean of 48.8 (SD = 8.9). Almost 44.6% of the study population has a PHS score of below 50; the MHS scores ranged from 28.4 to 67.6 with a mean of 50.8 (SD = 8.1). About 41.8% of the study population has an MHS score of below 50. Unemployment, household food insecurity and comorbidities with HIV were associated with both poor PHS and poor MHS scores. Age below 25 years and being a member of Christian fellowship were inversely associated with poor PHS. The least wealth index score and CD4 count below 350 cells/mL were also associated with poor MHS. Conclusion: Overall, socioeconomic inequalities and HIV-related clinical factors play an important role in improving the HRQoL of PLWHA. Many of these determinants are alterable risk factors. Appropriate strategies can improve the holistic management of chronic HIV care and maximize PLWHAs’ HRQoL. Such strategies require the adoption of comprehensive interventions, including policies and programmes that would improve the health, wellbeing and livelihood of PLWHA.


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