Effectiveness of Behavioral intervention among congenital heart defect children

Development in intensive care and medical treatment has significantly lowered mortality rates for children with complex congenital heart disease (CHD) but among pediatric survivors with complex CHD, there is a distinctive pattern of neuro-developmental and neuropsychology impairment characterized impaired social interaction, impulsive Behavior, and impaired executive functions. Children with congenital heart diseases have more Behavioral problems compared to children without chronic illnesses. Sample and sampling: The sample of 200 children with congenital heart defect was selected between age group 4-8 years using multistage stratified sampling. Method: The childhood psychopathology measurement schedule (CPMS) by Dr. Savitha Malhotra was used for assessing Behavioral problems present in children with CHD. The present investigation adopted an experimental design, described as “Pre- Post experimental design and the results were statistically analyzed using paired T test. Result: The result revealed that the effectiveness of intervention program to retrain Behavior showed high significance. Conclusion: With increased survival rates, the focus of clinical research has paralleled the population shift from short term surgical survival to the assessment of long-term morbidityKeyword: Congenital Heart Defect, Neuro-psychological retraining, Neurodevelopment, Behavioral and emotional retraining.

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Cohort study of intervened functionally univentricular heart in England and Wales (2000–2018)

Heart ◽

10.1136/heartjnl-2021-319677 ◽

2021 ◽

pp. heartjnl-2021-319677

Author(s):

Elena Hadjicosta ◽

Rodney Franklin ◽

Anna Seale ◽

Oliver Stumper ◽

Victor Tsang ◽

...

Keyword(s):

Cohort Study ◽

Congenital Heart ◽

Heart Diseases ◽

Survival Rates ◽

Outcome Data ◽

Complex Congenital Heart Disease ◽

Univentricular Heart ◽

Term Outcome ◽

Long Term Outcome ◽

Treatment Pathways

ObjectiveGiven the paucity of long-term outcome data for complex congenital heart disease (CHD), we aimed to describe the treatment pathways and survival for patients who started interventions for functionally univentricular heart (FUH) conditions, excluding hypoplastic left heart syndrome.MethodsWe performed a retrospective cohort study using all procedure records from the National Congenital Heart Diseases Audit for children born in 2000–2018. The primary outcome was mortality, ascertained from the Office for National Statistics in 2020.ResultsOf 53 615 patients, 1557 had FUH: 55.9% were boys and 67.4% were of White ethnic groups. The largest diagnostic categories were tricuspid atresia (28.9%), double inlet left ventricle (21.0%) and unbalanced atrioventricular septal defect (AVSD) (15.2%). The ages at staged surgery were: initial palliation 11.5 (IQR 5.5–43.5) days, cavopulmonary shunt 9.2 (IQR 6.0–17.1) months and Fontan 56.2 (IQR 45.5–70.3) months. The median follow-up time was 10.8 (IQR 7.0–14.9) years and the 1, 5 and 10-year survival rates after initial palliation were 83.6% (95% CI 81.7% to 85.4%), 79.4% (95% CI 77.3% to 81.4%) and 77.2% (95% CI 75.0% to 79.2%), respectively. Higher hazards were present for unbalanced AVSD HR 2.75 (95% CI 1.82 to 4.17), atrial isomerism HR 1.75 (95% CI 1.14 to 2.70) and low weight HR 1.65 (95% CI 1.13 to 2.41), critical illness HR 2.30 (95% CI 1.67 to 3.18) or acquired comorbidities HR 2.71 (95% CI 1.82 to 4.04) at initial palliation.ConclusionAlthough treatment pathways for FUH are complex and variable, nearly 8 out of 10 children survived to 10 years. Longer-term analyses of outcome based on diagnosis (rather than procedure) can inform parents, patients and clinicians, driving practice improvements for complex CHD.

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DOUBLE ANEUPLOIDY 48,XXY,+21 ASSOCIATED WITH A CONGENITAL HEART DEFECT IN A NEONATE

Balkan Journal of Medical Genetics ◽

10.2478/bjmg-2013-0038 ◽

2013 ◽

Vol 16 (2) ◽

pp. 85-89 ◽

Cited By ~ 1

Author(s):

X. Shu ◽

C. Zou ◽

Z. Shen

Keyword(s):

Congenital Heart Defect ◽

Congenital Heart ◽

Septal Defect ◽

Klinefelter Syndrome ◽

Complex Congenital Heart Disease ◽

Valve Regurgitation ◽

Secundum Atrial Septal Defect ◽

Tricuspid Valve Regurgitation ◽

Heart Defect ◽

Double Aneuploidy

ABSTRACT A neonate with a double aneuploidy associated with congenital heart defect (CHD) suffered from cyanosis after birth. He had typical features of Down syndrome (DS) including hypertelorism, slightly lowset ears with protruding pinna. Doppler echocardiography indicated complex congenital heart disease with an ostium secundum atrial septal defect, enlarged right ventricle, and mild tricuspid valve regurgitation. Further chromosomal analysis showed a karyotype of 48,XXY,+21: a double aneuploidy of DS and Klinefelter syndrome (KS). Until now, only seven cases of double aneuploidy associated with CHD defect have been reported

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Fetal echocardiography - 25-year experience in Serbia

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh180130018v ◽

2019 ◽

Vol 147 (1-2) ◽

pp. 70-73

Author(s):

Svetlana Vrzic-Petronijevic ◽

Milos Petronijevic ◽

Vojislav Parezanovic ◽

Jelena Stamenkovic-Dukanac ◽

Zorica Jestrovic ◽

...

Keyword(s):

Congenital Heart Defect ◽

Congenital Heart ◽

Fetal Heart ◽

Heart Diseases ◽

Fetal Echocardiography ◽

Heart Defects ◽

Pathological Finding ◽

Congenital Heart Diseases ◽

Heart Defect ◽

Specificity And Sensitivity

Introduction/Objective. Congenital heart diseases are the most common congenital anomalies. The objective of the study was to determine reliability, specificity, and sensitivity of fetal echocardiography in detection of congenital heart diseases in a referral center for fetal echocardiography. Methods. We analyzed 14,500 fetal echocardiography exams (FEC) between 1991 and 2014, performed in two tertiary centers. Results. The average maternal age at the time of diagnosis was 32 years. The mean gestational age at the time of diagnosis was 25.9 weeks. The most common indications for FEC were suspicious abnormal cardiac findings in obstetrical screening sonography (50.6%). Among 9,055 examined fetuses, pathological finding on the fetal heart was found in 638 cases. The most common congenital heart diseases were structural anomalies of the fetal heart in 81%, of which 13.3% were fetuses with hypoplastic left heart syndrome and 11.2% with ventricular septal defect. Of all fetuses with diagnosed congenital heart defect, 46.2% were born alive and had good postnatal prognosis, while 2.7% died in utero, and 10.6% died in the early neonatal period. Pregnancy was terminated in 40.4% of fetuses with severe congenital heart defect. Sensitivity of the diagnostic procedure in our study was 95.9%, and specificity was 99.9%. Conclusion. Our study proves that FEC is a reliable, informative diagnostic tool in detecting congenital heart defects with high specificity and sensitivity. With multidisciplinary approach, it provides an optimal time window for improving perinatal outcome.

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