scholarly journals Iodinated contrast media

2021 ◽  
Vol 9 (1) ◽  
pp. 156-167
Author(s):  
Sami S. Alshowiman ◽  
Abdullah H Sahrah ◽  
Ayman K. Alswailem ◽  
Saud F. Alotaibi ◽  
Abdulaziz A. ALtowaijiri ◽  
...  

Contrast media are the materials utilized in radiology to improve the visualization of certain body structures subjected to analysis in a medical image. Contrast media are, then, diagnostic drugs because they increase the visibility of organs and tissues and allow the identification of details that otherwise could not be observed. With the introduction of multidetector computed tomography the number of patients undergoing contrast studies has grown exponentially in recent years. In computed tomography the formation of the radiographic image is obtained with the use of contrast media containing iodine atoms, exploiting the different attenuation that the X-ray beam presents in crossing the anatomical districts. The Iodinated Contrast Media (ICM) are a category of numerous substances formed by even complex molecules that vary considerably in their properties, uses and toxic effects. Even though iodinated contrast agents have a good safety profile, it is necessary to understand that some patients can have severe, life-threatening allergic reactions because of the side effects of the chemicals. This paper describes the clinical pharmacology, use and adverse reactions of intravenous iodinated contrast media used in computerized tomography, offering all doctors, even non-radiologists, the opportunity for rapid updating.

2007 ◽  
Vol 15 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Beatriz Cavalcanti Juchem ◽  
Clarice Maria Dall'Agnol

This exploratory-descriptive, non-experimental quantitative research aimed to learn about immediate adverse reactions to intravenous iodinated contrast media in hospitalized patients submitted to computed tomography at a teaching hospital in the South of Brazil. During the study period, all adverse reactions showed mild intensity, at a frequency of 12.5% with ionic iodinated contrast media, and 1% with non-ionic contrast agent. The extravasation of contrast occurred in 2.2% of the injections in a peripheral vein without complications in any of the cases. The results are within the limits cited in international literature and suggest that tomography service professionals should know their own rates of adverse reactions to iodinated contrast agent, as well as the conditions in which they occur, in order to obtain evidence to evaluate the respective care delivery processes.


2020 ◽  
Author(s):  
Callum P. Scotson ◽  
Arjen van Veelen ◽  
Katherine A. Williams ◽  
Nicolai Koebernick ◽  
Dan McKay Fletcher ◽  
...  

Abstract Aims We sought to develop a novel experimental system which enabled application of iodinated contrast media to in vivo plant roots intact in soil and was compatible with time-resolved synchrotron X-ray computed tomography imaging. The system was developed to overcome issues of low contrast to noise within X-ray computed tomography images of plant roots and soil environments, the latter of which can complicate image processing and result in the loss of anatomical information. Methods To demonstrate the efficacy of the system we employ the novel use of both synchrotron X-ray computed tomography and synchrotron X-ray fluorescence mapping to capture the translocation of the contrast media through root vasculature into the leaves. Results With the application of contrast media we identify fluid flow in root vasculature and visualise anatomical features, which are otherwise often only observable in ex vivo microscopy, including: the xylem, metaxylem, pith, fibres in aerenchyma and leaf venation. We are also able to observe interactions between aerenchyma cross sectional area and solute transport in the root vasculature with depth. Conclusions Our novel system was capable of successfully delivering sufficient contrast media into root and leaf tissues such that anatomical features could be visualised and internal fluid transport observed. We propose that our system could be used in future to study internal plant transport mechanisms and parameterise models for fluid flow in plants.


2018 ◽  
Vol 13 (2) ◽  
pp. 437-443 ◽  
Author(s):  
Hirokazu Saito ◽  
Kana Noda ◽  
Koji Ogasawara ◽  
Shutaro Atsuji ◽  
Hiroko Takaoka ◽  
...  

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