scholarly journals Cutaneous Polyarteritis Nodosa (cPAN) in ab 5 Years Old Girl

2018 ◽  
Vol 2 (5) ◽  
Author(s):  
Lubna Nazir

Polyarteritis nodosa is a rare form of systemic vasculitis. Cutaneous polyarteritis nodosa (cPAN) is subtype of systemic PAN which predominantly affects the skin, extra-cutaneous findings include fever, malaise, myalgias, arthralgias, and neuropathy. The true incidence of cutaneous PAN is unknown. cPAN is recognized as a separate entity and is essentially a benign disorder which should be distinguished from systemic PAN, as the clinical course and management of the two conditions is different. In this case report, we have described a patient with fever and gangrene of both hands and feet. The patient underwent a very extensive workup in order to determine the cause of her condition, which finally turned out cPAN on skin biopsy

2012 ◽  
Vol 29 (4) ◽  
pp. 473-478 ◽  
Author(s):  
Victoria L. Williams ◽  
Ricardo Guirola ◽  
Kristy Flemming ◽  
Gunjan M. Modi ◽  
Cecilia Rosales ◽  
...  

2005 ◽  
Vol 53 (3) ◽  
pp. 468-470 ◽  
Author(s):  
Brent Culver ◽  
Aleksandr Itkin ◽  
Ken Pischel

2020 ◽  
Vol 4 (2) ◽  
pp. 272-277
Author(s):  
Takahiro Iwata ◽  
Hiromu Ito ◽  
Moritoshi Furu ◽  
Masahiro Ishikawa ◽  
Masayuki Azukizawa ◽  
...  

2018 ◽  
Vol 22 (5) ◽  
pp. 516-518 ◽  
Author(s):  
Derek To ◽  
Scott Bradshaw ◽  
Jennifer Lipson

Polyarteritis nodosa (PAN) is a rare vasculitis affecting medium-sized vessels. Cutaneous PAN is a clinical variant, and we report the first case of empagliflozin-induced cutaneous PAN in a 69-year-old man. After starting empagliflozin, the patient presented with tender subcutaneous nodules on his legs, which showed a medium-sized vessel vasculitis on histopathology. Upon cessation of this medication, he had full resolution of these nodules. This case illustrates that empagliflozin can induce cutaneous PAN, and further attention to this medication’s association with cutaneous PAN is warranted.


2018 ◽  
Vol 89 (10) ◽  
pp. A36.2-A36
Author(s):  
Jonathan Cleaver ◽  
Shelley Renowden ◽  
Mario Teo ◽  
Philip Clatworthy

A 50-year-old female was admitted following a subacute and increasing headache, numbness in both hands and feet, generalised weakness and confusion.An MRI brain revealed an acute left temporal infarct with multi-focal established infarcts. MR angiography demonstrated marked occlusive disease affecting terminal internal carotid artery and both middle cerebral and posterior cerebral arteries, in a potential Moyamoya pattern.Lumbar puncture, extensive blood tests and echocardiography were unremarkable. A skin biopsy showed intimal thickening of the deep dermal arteries compatible with a diagnosis of Sneddon Syndrome. Livedo reticularis was absent and antiphospholipid antibodies negative. Antiplatelet therapy only was commenced given her seronegativity and Moyamoya.DiscussionSneddon syndrome is an uncommon disorder, characterised as generalised livedo reticularis with stroke (Sneddon, 1965). It is an increasingly recognised cause of ischaemic stroke in young adults, however, its clinical course remains poorly defined in the literature (Boesch et al. 2003). It is increasingly associated with Moyamoya syndrome, posing a challenge in terms of anticoagulation in these patients (Fierini et al. 2015). To our knowledge, this is only the second reported case without livedo reticularis (Marianetti et al. 2011) - highlighting the importance of skin biopsy - and the first with this clinical and radiological combination.


2016 ◽  
Vol 8 (1) ◽  
pp. 74
Author(s):  
Md. Mahabubur Rahaman ◽  
Md Rahmat Ullah Siddique ◽  
Md Aminul Islam ◽  
Md. Moksedur Rahman ◽  
Md. Zahed Parvez Barbhuiyan ◽  
...  

Linear psoriasis is a rare form of disease which is very difficult to differentiate from inflammatory linear verrucous epidermal nevus. Sometimes clinical history, physical examination and histopathology analysis may not be sufficient to confirm the diagnosis. We report a case of25 year-old male presented with a linear plaque covered with silvery scales on left upper extremity extending from tip of the index to mid forearm for last 2 years. A skin biopsy was consistent with psoriasis, and the unilateral distribution in a linear pattern led to a diagnosis of linear psoriasis, which is a rare variant of psoriasis. Although histopathologically it can be difficult to distinguish from inflammatory linear verrucous epidermal nevus (ILVEN), linear psoriasis presents in adulthood and responds to conventional topical antipsoriatic therapies.


2021 ◽  
Author(s):  
Reinan Tavares Campos ◽  
Lucia Maria Mattei Arruda Campos ◽  
Clovis Arthur A Silva ◽  
Pedro Vale Bede ◽  
Maria Fernanda Badue Pereira ◽  
...  

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Emmanuel Ribeiro ◽  
Thomas Cressend ◽  
Pierre Duffau ◽  
Marieke Grenouillet-Delacre ◽  
Marie Rouanet-Larivière ◽  
...  

Polyarteritis nodosa (PAN) is a systemic vasculitis whose severe forms are treated with glucocorticoids and cyclophosphamide. Refractory patients are exposed to many complications, notably accelerated atherosclerosis. We report a case report of 71-year-old man followed for polyarteritis nodosa refractory to glucocorticoids and cyclosphosphamide. Systemic vasculitis relapses are followed to accelerated atherosclerosis: severe ischemic lesions led to amputation of lower limbs. Remission of refractory PAN is obtained with rituximab. Disappearance of biological inflammatory is allowed to regression of ischemic lesions in upper limbs. In this situation, we recommend a systematic vascular work-up for patients suffered from refractory vasculitis. On the other hand, therapeutic trials are needed to determine the real efficacy and place of rituximab in the treatment of polyarteritis nodosa.


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