scholarly journals Anesthetic Management of a Patient with Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Symptoms (MELAS): A Case Report

2021 ◽  
Vol 5 (10) ◽  
pp. 04-07
Author(s):  
Refaat Shehab ◽  
MO Ababneh
Keyword(s):  
Case Report ◽  
Lactic Acidosis ◽  
Anesthetic Management ◽  
Mitochondrial Encephalopathy

Anesthetic Management of Mitochondrial Encephalopathy With Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome) in a High-Risk Pregnancy

2017 ◽  
Vol 9 (2) ◽  
pp. 38-41 ◽  
Author(s):  
Josh D. Bell ◽  
Kushlin Higgie ◽  
Mital Joshi ◽  
Joshua Rucker ◽  
Sahar Farzi ◽  
...  
Keyword(s):  
High Risk ◽  
Lactic Acidosis ◽  
Anesthetic Management ◽  
High Risk Pregnancy ◽  
Melas Syndrome ◽  
Mitochondrial Encephalopathy ◽  
Risk Pregnancy

scholarly journals General anesthesia with remimazolam in a patient with mitochondrial encephalomyopathy: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuji Suzuki ◽  
Matsuyuki Doi ◽  
Yoshiki Nakajima
Keyword(s):  
Lactic Acidosis ◽  
General Anesthesia ◽  
Mitochondrial Disease ◽  
Muscle Relaxation ◽  
Anesthetic Management ◽  
Perioperative Period ◽  
Mitochondrial Encephalomyopathy ◽  
Anesthesia Induction ◽  
General Anesthetic ◽  
Anesthetic Agents

Abstract Background Systemic anesthetic management of patients with mitochondrial disease requires careful preoperative preparation to administer adequate anesthesia and address potential disease-related complications. The appropriate general anesthetic agents to use in these patients remain controversial. Case presentation A 54-year-old woman (height, 145 cm; weight, 43 kg) diagnosed with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes underwent elective cochlear implantation. Infusions of intravenous remimazolam and remifentanil guided by patient state index monitoring were used for anesthesia induction and maintenance. Neither lactic acidosis nor prolonged muscle relaxation occurred in the perioperative period. At the end of surgery, flumazenil was administered to antagonize sedation, which rapidly resulted in consciousness. Conclusions Remimazolam administration and reversal with flumazenil were successfully used for general anesthesia in a patient with mitochondrial disease.

scholarly journals Anesthetic management for cesarean delivery in a woman with congenital atlantoaxial dislocation and Chiari type I anomaly: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yuyan Nie ◽  
Weimin Zhou ◽  
Shaoqiang Huang
Keyword(s):  
Case Report ◽  
Cesarean Delivery ◽  
Anesthetic Management ◽  
Neurological Complications ◽  
Atlantoaxial Dislocation ◽  
Epidural Needle ◽  
Team Approach ◽  
Anesthetic Techniques ◽  
Type I ◽  
Combined Spinal Epidural Anesthesia

Abstract Background The preferable choice of anesthesia for the patients with congenital atlantoaxial dislocation (CAAD) and type I Arnold Chiari malformations (ACM-I) has been a very confusing issue in clinical practice. We describe the successful administration of combined spinal-epidural anesthesia for a woman with CAAD and ACM-1 accompanied by syringomyelia. Case presentation Our case report presents the successful management of a challenging obstetric patient with CAAD and ACM-1 accompanied by syringomyelia. She had high risks of difficult airway and aspiration. The injection of bolus drugs through the spinal or epidural needle may worsen the previous neurological complications. The patient was well evaluated with a multidisciplinary technique before surgery and the anesthesia was provided by a skilled anesthesiologist with slow spinal injection. Conclusions An interdisciplinary team approach is needed to weigh risks and benefits for patients with CAAD and ACM-1 undergoing cesarean delivery. Therefore, an individual anesthetic plan should be made basing on the available anesthetic equipments and physicians’ clinical experience on anesthetic techniques.

scholarly journals When a harmless procedure causes a life-threatening problem: a case report of metformin-associated lactic acidosis following a colonoscopy

2019 ◽  
Vol 36 (1) ◽  
pp. 22-24 ◽  
Author(s):  
Ana Pessoa ◽  
José Quintela ◽  
Sofia Tavares ◽  
Marta Marques ◽  
Joana Pereira ◽  
...  
Keyword(s):  
Case Report ◽  
Lactic Acidosis ◽  
Life Threatening
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