Treatment of Sterility and Habitual Abortion with Wheat-Germ and Wheat-Germ Oil (Vitamin E)

1933 ◽  
Vol 13 (3) ◽  
pp. 219-227 ◽  
Author(s):  
P. Vogt-möller
Author(s):  
Hadeer Zakaria ◽  
Tarek M. Mostafa ◽  
Gamal A. El-Azab ◽  
Nagy AH Sayed-Ahmed

Abstract. Background: Elevated homocysteine levels and malnutrition are frequently detected in hemodialysis patients and are believed to exacerbate cardiovascular comorbidities. Omega-3 fatty acids have been postulated to lower homocysteine levels by up-regulating metabolic enzymes and improving substrate availability for homocysteine degradation. Additionally, it has been suggested that prevention of folate depletion by vitamin E consumption decreases homocysteine levels. However, data on the effect of omega-3 fatty acids and/or vitamin E on homocysteine levels and nutritional status have been inconclusive. Therefore, this study was planned to examine the effect of combined supplementation of fish oil, as a source of omega-3 fatty acids, with wheat germ oil, as a source of vitamin E, on homocysteine and nutritional indices in hemodialysis patients. Methods: This study was a randomized, double-blind, placebo-controlled trial. Forty-six hemodialysis patients were randomly assigned to two equally-sized groups; a supplemented group who received 3000 mg/day of fish oil [1053 mg omega-3 fatty acids] plus 300 mg/day of wheat germ oil [0.765 mg vitamin E], and a matched placebo group who received placebo capsules for 4 months. Serum homocysteine and different nutritional indices were measured before and after the intervention. Results: Twenty patients in each group completed the study. At the end of the study, there were no significant changes in homocysteine levels and in the nutritional indices neither in the supplemented nor in the placebo-control groups (p > 0.05). Conclusions: Fish oil and wheat germ oil combination did not produce significant effects on serum homocysteine levels and nutritional indices of hemodialysis patients.


1967 ◽  
Vol 56 (2_Suppla) ◽  
pp. S5-S15 ◽  
Author(s):  
W. Richard Dukelow

ABSTRACT Wheat germ oil is a biochemical complex containing many substances. Many of these are unidentified at the present time. In the past, confusion has existed due to the assumed equivalence of wheat germ oil and vitamin E and this has resulted, in several instances, of misinterpretation of research data. With recent discoveries of beneficial effects of wheat germ oil on reproductive processes in humans, cattle, sheep and laboratory animals, as well as the physiological effects on oxygen uptake and endurance of both wheat germ oil and octacosanol, it appears that a reevaluation of these natural products would be in order.


1931 ◽  
Vol 87 (4) ◽  
pp. 165-170
Author(s):  
P. Vogt-Moller ◽  
F. Bay
Keyword(s):  

1936 ◽  
Vol 31 (2) ◽  
pp. 352-358 ◽  
Author(s):  
E.Macbeth Watson ◽  
W.Pelton Tew
Keyword(s):  

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