Protective Effects of Caffeic Acid Phenethyl Ester on Retinal Ischemia/Reperfusion Injury in Rats

2010 ◽  
Vol 35 (10) ◽  
pp. 930-937 ◽  
Author(s):  
Yuhua Shi ◽  
Xingwei Wu ◽  
Yuanyuan Gong ◽  
Yating Qiu ◽  
Hongmei Zhang ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Caffeic Acid ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Caffeic Acid Phenethyl Ester ◽  
Retinal Ischemia ◽  
Protective Effects

scholarly journals Protective effects of dehydroepiandrosterone (DHEA) vs caffeic acid phenethyl ester (CAPE) against ischemia-reperfusion injury in rat ovary

2020 ◽  
Vol 7 (1) ◽  
pp. 384-389
Author(s):  
Ali Doğukan Angın ◽  
Önder Sakin ◽  
Muzaffer Seyhan Cıkman ◽  
İsmet Gün ◽  
Ramazan Denizli ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Caffeic Acid ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Caffeic Acid Phenethyl Ester ◽  
Ovarian Torsion ◽  
Albino Rats ◽  
Protective Effects ◽  
Primordial Follicles ◽  
The Third

Objective: In this study, the effectiveness of caffeic acid phenethyl ester (CAPE) and Dehydroepiandrosterone (DHEA) in preventing ischemia reperfusion injury associated with ovarian torsion have been investigated. Materials and Methods: Twenty four adult female Wistar Albino rats were randomly divided into four groups. Ovaries were not twisted, and only healthy ovarian tissues were removed from the rats in the first group, while ovaries were twisted for 3 hours in the other groups. The second group did not receive any medications before the ovaries were untwisted, while 20 micromole/kg of CAPE was applied on peritoneal surface to the third group, and 60 mg/kg of DHEA was administered intraperitoneally to the fourth group. Results: The level of primordial follicles was higher in the third group compared to the second group after the torsion of the ovary (p=0.017). The mean level of primary follicles was higher in the first group compared to the number of follicles in the third and fourth groups after the torsion of the ovary (p<0.001). The median hemorrhage level was higher in the second group following ovarian torsion compared to that in the first group (p=0.005). Conclusion: Agents that have been considered to reduce injury resulting from ischemia-reperfusion proved ineffective during the early stages in terms of the number of follicles in the ovaries; however, we believe that long-term studies may be more beneficial.

The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats

2014 ◽  
Vol 33 (4) ◽  
pp. 283-288 ◽  
Author(s):  
Baran Gencer ◽  
Turan Karaca ◽  
Hasan Ali Tufan ◽  
Selçuk Kara ◽  
Sedat Arikan ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Retinal Ischemia ◽  
Protective Effects
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