Mutagenic-Carcinogenic Relationships and the Role of Mutagenic Screening Tests for Carcinogenicity

1976 ◽  
Vol 9 (5) ◽  
pp. 761-771 ◽  
Author(s):  
Lionel A. Poirier ◽  
Vincent F. Simmon
Keyword(s):  
Angiology ◽  
2016 ◽  
Vol 68 (5) ◽  
pp. 441-446 ◽  
Author(s):  
Mehmet Karaduman ◽  
Mustafa Aparci ◽  
Murat Unlu ◽  
Cengiz Ozturk ◽  
Sevket Balta ◽  
...  

The prevalence of hypertension is increasing among young population worldwide. So there is an interest in detecting prehypertension and hypertension in childhood. We determined blood pressure (BP) recorded at a screening test in a young population. We retrospectively evaluated the medical records including systolic blood pressure (SBP), diastolic blood pressure (DBP), weight, height, and body mass index (BMI) of 685 male and 130 female apparently healthy adolescents. We evaluated the prevalence of BP categories: normotension, prehypertension, and hypertension. The prevalence of normotension (n = 369), prehypertension (n = 333), and hypertension (n = 113) was 45.3%, 40.9% and 13.9%, respectively; prehypertension and hypertension were significantly higher among males. The prevalence of prehypertension and hypertension was significantly higher among overweight males and females. The BMI significantly correlated with SBP, DBP, and heart rate among both genders. The prevalence of prehypertension and hypertension is high among Turkish adolescents. Screening tests focused on BP and BMI measurement may help detect the young population at risk of hypertension and cardiovascular disease in the future.


2008 ◽  
Vol 16 (1) ◽  
pp. 9-13 ◽  
Author(s):  
H.P. PATI ◽  
A.K. SARAYA ◽  
V.D. CHARAN ◽  
K.R. SUNDARAM ◽  
M.C. SHARMA ◽  
...  

2014 ◽  
Vol 24 (10) ◽  
pp. 2435-2448 ◽  
Author(s):  
Ji Yang Kim ◽  
Se Hyung Kim ◽  
Soo Young Kim

2000 ◽  
Vol 9 (3) ◽  
pp. 158-165 ◽  
Author(s):  
RF Reiss

Severe hemostatic defects that occur during massive transfusion are related to the volume of blood transfused, preexisting hemostatic abnormalities, concomitant pathologic changes, and therapeutic maneuvers. The relative role of each factor in the bleeding can be rapidly determined by using routine clinical laboratory tests. This determination requires an understanding of the properties of selected clotting factors, what coagulation screening tests measure, how these tests behave as the levels of factors change, and test profiles characteristic of different defects. Screening tests include platelet count, prothrombin time, partial thromboplastin time, thrombin time, and fibrinogen level. These tests are generally available on an emergent basis and can be completed within 25 minutes. The pattern associated with hemodilution is universal in massive transfusion. Patterns characteristic of the other pathologic processes that may be encountered are simply superimposed on the characteristics of hemodilution. Successful management of the contributing causes of bleeding depends on the administration of the appropriate blood components in the dose necessary to ensure that the levels of platelets and clotting factors are returned to and maintained at hemostatic levels.


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