scholarly journals Roentgenologic appraisal of low back pains in Uyo, Nigeria

2013 ◽  
Vol 4 (2) ◽  
pp. 15-22 ◽  
Author(s):  
Felix Uduma ◽  
Tim E Nottidge ◽  
Dianabasi U Eduwem ◽  
Edwin N Dim
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Degenerative Disc Disease ◽  
Study Patient ◽  
Low Back ◽  
Disc Disease ◽  
Cross Sectional ◽  
Degenerative Disc ◽  
Number Of Patients ◽  
Anterior Posterior

Background: Low back pain is one of the commonest indices for referral to radiological evaluation of lumbo-sacral spine. The underlying pathology may be divulged by the exploit of conventional lumbo-sacral radiography. Purpose: By collating and analysing the lumbo-sacral radiographs of patients with low back pain, we hope to give an account of the accompaniments of low back pain and where possible, to deduce its causes in our local environ. Study design/Setting: A cross-sectional prospective study. Patient Sample: Two hundred and forty patients were enrolled in the study Outcome Measures: Pathologies were evaluated based on features seen on the paired lumbo-sacral radiographs of anterior-posterior and lateral. Methods: Anterior-posterior and lateral plain radiographs were done under standardized conditions after recording of patient’s biodata. Radiographs were analysed using SSPS 13 statistical computer package. Results: A total of 240 patients aged 10-89years with mean age of 48.9 and standard deviations of 25.4 were studied. Males were 130 while females were 110. The number of identifiable pathologies (n= 257) outweighed the number of patients (n=240). The commonest pathology was degenerative disc disease. This was seen in 67.5% of studied population. 15.83% had either normal radiographs, loss of lumbar lordosis or scoliosis. Conclusions: Degenerative disc disease is the commonest pathology seen in patients with low back pain in Uyo, Nigeria.DOI: http://dx.doi.org/10.3126/ajms.v4i2.6470 Asian Journal of Medical Sciences 4(2013) 15-22

Subclinical Infection and Disc Dysbiosis as a Cause of Degenerative Disc Disease and Low Back Pain

2020 ◽  
Author(s):  
S. Rajasekaran ◽  
S. Dilip Chand Raja ◽  
Chitraa Tangavel ◽  
M. Raveendran ◽  
K. S. Sri Vijay Anand ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Degenerative Disc Disease ◽  
Low Back ◽  
Subclinical Infection ◽  
Disc Disease ◽  
Degenerative Disc

scholarly journals Cell-Based Therapies Used to Treat Lumbar Degenerative Disc Disease: A Systematic Review of Animal Studies and Human Clinical Trials

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
David Oehme ◽  
Tony Goldschlager ◽  
Peter Ghosh ◽  
Jeffrey V. Rosenfeld ◽  
Graham Jenkin
Keyword(s):  
Stem Cells ◽  
Clinical Trials ◽  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Degenerative Disc Disease ◽  
Low Back ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Disc Regeneration

Low back pain and degenerative disc disease are a significant cause of pain and disability worldwide. Advances in regenerative medicine and cell-based therapies, particularly the transplantation of mesenchymal stem cells and intervertebral disc chondrocytes, have led to the publication of numerous studies and clinical trials utilising these biological therapies to treat degenerative spinal conditions, often reporting favourable outcomes. Stem cell mediated disc regeneration may bridge the gap between the two current alternatives for patients with low back pain, often inadequate pain management at one end and invasive surgery at the other. Through cartilage formation and disc regeneration or via modification of pain pathways stem cells are well suited to enhance spinal surgery practice. This paper will systematically review the current status of basic science studies, preclinical and clinical trials utilising cell-based therapies to repair the degenerate intervertebral disc. The mechanism of action of transplanted cells, as well as the limitations of published studies, will be discussed.

scholarly journals Diagnosing Discogenic Low Back Pain Associated with Degenerative Disc Disease Using a Medical Interview

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0166031 ◽  
Author(s):  
Juichi Tonosu ◽  
Hirohiko Inanami ◽  
Hiroyuki Oka ◽  
Junji Katsuhira ◽  
Yuichi Takano ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Degenerative Disc Disease ◽  
Low Back ◽  
Medical Interview ◽  
Disc Disease ◽  
Degenerative Disc ◽  
Discogenic Low Back Pain

scholarly journals Surgical outcomes of patients with degenerative lumbar disc disease post-IntraSPINE® device fixation: Three-year prospective study

2021 ◽  
Vol 8 (1) ◽  
pp. 01-10
Author(s):  
Doan Co-Minh
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Degenerative Disc Disease ◽  
Radicular Pain ◽  
Low Back ◽  
Disc Disease ◽  
Mixed Effect ◽  
Lumbar Degenerative Disc Disease ◽  
Degenerative Disc ◽  
Prospective Longitudinal

Background: Lumbar degenerative disc disease is one of the most common conditions associated with chronic low back pain. IntraSPINE® is a novel inter-laminar device that allows more physiological rocking-type movements in flexion and extension. Aim: To evaluate the results of patients with symptomatic Lumbar degenerative disc disease treated with an IntraSPINE® device and followed up over a 3-year period. Materials and Methods: A Prospective longitudinal research study involving patients with imaging-confirmed Lumbar degenerative disc disease in whom conservative treatment was unsuccessful. Outcome measures were changes over baseline score on the Oswestry Disability Index (ODI), and low back and radicular pain assessed at 6, 12, 24 and 36 months postoperatively. Overall success, a composite outcome that included key safety and clinical considerations, was assessed. Secondary outcomes included satisfaction with symptoms, employment status and post-surgery medical interventions. To compare differences in longitudinal clinical score patterns over 36 months, a mixed-effect model ANCOVA with repeated measurements was performed, with adjustment for low back and radicular pain score and ODI score at baseline. Results: 231 patients were recruited and 180 completed the study. A significant improvement in ODI score (p=0.0597), as well as in VAS (Visual Analogue Scale) scores for back (p= 0.0228) and leg pain (p<0.0001) was observed during the follow-up. For ODI score, the mean percentage decrease from inclusion to month 36 was 64.5%. These scores were respectively 66.2% for radicular pain and 46.4% for low back pain. In 73% of cases, surgery was considered successful. 89% of working patients returned to work and 68% of patients were very satisfied at month 12. Only four patients presented intraoperative complications.

scholarly journals One decade follow up after nucleoplasty in the management of degenerative disc disease causing low back pain and radiculopathy

2015 ◽  
Vol 10 (1) ◽  
pp. 21 ◽  
Author(s):  
Amit Agrawal ◽  
Rafael Cincu ◽  
Francisco Lorente ◽  
Joaquin Gomez ◽  
Jose Eiras
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Degenerative Disc Disease ◽  
Low Back ◽  
Disc Disease ◽  
Degenerative Disc

scholarly journals Low back pain and degenerative disc disease

2006 ◽  
Vol 59 (9-10) ◽  
pp. 456-461 ◽  
Author(s):  
Slavica Jandric ◽  
Branislav Antic
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Physical Therapy ◽  
Degenerative Disc Disease ◽  
Pharmacological Therapy ◽  
Low Back ◽  
Disc Disease ◽  
Discogenic Pain ◽  
Degenerative Disc ◽  
Clinical Conditions

Introduction. Various clinical conditions can cause low back pain, and in most cases it is of a degenerative origin. Degenerative disc disease is a common condition which affects young to middle-aged men and women equally. Changes in the mechanical properties of the disc lead to degenerative arthritis in the intervertebral joints, osteophytes, and narrowing the intervertebral foramen or the spinal canal. Pathophysiology. Degenerative cascade, described by Kirkaldy-Willis, is the widely accepted pathophysiologic model describing the degenerative process as it affects the lumbar spine in 3 phases. Diagnosis. There are two forms of low back pain secondary to degenerative disc disease: a) lumbalgia and b) lumbar radiculopathy. Limitation of movement, problems with balance, pain, loss of reflexes in the extremities, muscle weakness, loss of sensation or other signs of neurological damage can be found on physical examination. For accurate diagnosis, it is often necessary to combine clinical examination and sophisticated technology. Treatment. Coservative treatment consists of rest, physical therapy, pharmacological therapy and injection therapy. Physical rehabilitation with active patient participation is a key approach to treatment of patients with discogenic pain. Physical therapy, occupational therapy and kinesitherapy are important for improving muscle strength, endurance, and flexibility. Disc surgery is performed if surgical intervention is required. .

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