Reversal of Ischemic Hepatitis after Cardiac Surgery under Cardiopulmonary Bypass: A Case Report

2020 ◽  
Vol 3 (2) ◽  
pp. 36-37
Author(s):  
Lokesh Shekher Jaiswal ◽  
Narendra Pandit ◽  
Jagat Narayan Prasad
Keyword(s):  
Cardiac Surgery ◽  
Case Report ◽  
Cardiopulmonary Bypass ◽  
Mitral Valve ◽  
Cardiogenic Shock ◽  
Valve Replacement ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Acute Hepatic Failure ◽  
Ischemic Hepatitis

Acute hepatic failure due to ischemic hepatitis is associated with high mortality. The safety of cardiopulmonary bypass in this setting is not fully described. Here we report a case of a 21-year-old female who developed an acute fulminant hepatic failure due to ischemic hepatitis following a cardiogenic shock. She underwent subsequent successful mitral valve replacement under cardiopulmonary bypass, thus providing an evidence of its safety in acute fulminant hepatic failure.

scholarly journals Cardiac surgery in patients with heparin induced thombocytopenia (HIT II)

2009 ◽  
Vol 56 (1) ◽  
pp. 47-52
Author(s):  
M.D. Jovic ◽  
D.G. Nezic ◽  
B.M. Calija ◽  
D.S. Nenadic ◽  
A.M. Knezevic ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Anticoagulant Therapy ◽  
Anticoagulation Therapy ◽  
Thrombin Inhibitors ◽  
Postoperative Treatment ◽  
Per Oral

Heparin-induced thrombocytopenia (HIT) might be lifethreatening in patients undergoing open heart surgery, due to thromboembolic events, thrombocytopenia and bleeding. If cardiac surgery with cardiopulmonary bypass (CPB) is necessary, anticoagulation therapy will be based on usage of danaparoid or direct thrombin inhibitors. Female patient was switched from per oral anticoagulant therapy to low molecular heparin therapy preparing for reredo mitral valve replacement due to endocarditis and artificial valve thrombosis. In next 10 days, thrombocytopenia was obvious (Tr 302 000 mm3 to 11 000 mm3) , and diagnoses of HIT were done. Anticoagulant therapy was continued with danaparoid, 750 IU/12 h sc. During the surgery, reredo mitral valve replacement and aortocoronary bypass on anterior descending coronary artery, blood salvage technique with rhirudin( intravenous bolus 0,4 mg/kg, in CPB prajming solution 0,4mg/kg and continuous infusion during CPB 0,15 mg/kg/h ) during cardiopulmonary bypass was used. Active coagulation time and +++ were monitored, without any sign of micro thrombosis in circuit. Postoperatively, per oral anticoagulation therapy was initiated with prolonged postoperative treatment due to basic disease, endocarditis. Patient was discharged from hospital on 21-st postoperative day without any complication.

scholarly journals Acute ischemic stroke secondary to cardiac embolus of a ‘foreign body’ material after a redo sternotomy for mitral valve replacement: A case report

2018 ◽  
Vol 25 (2) ◽  
pp. 208-211 ◽  
Author(s):  
Seán Fitzgerald ◽  
Asim Rizvi ◽  
Daying Dai ◽  
Eric E Williamson ◽  
Giuseppe Lanzino ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Ischemic Stroke ◽  
Case Report ◽  
Foreign Body ◽  
Mitral Valve ◽  
Acute Ischemic Stroke ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Increased Risk ◽  
Tricuspid Valve Annuloplasty

Summary Cardiac surgery has been shown to be associated with increased risk of acute ischemic stroke. This report presents a case of a successful mechanical embolectomy procedure to treat a patient for an acute ischemic stroke, which was caused by the cardiac embolization of a ‘foreign body’ containing debris following a redo sternotomy procedure for mitral valve replacement and tricuspid valve annuloplasty.

Tracheal reconstruction with mitral valve replacement under cardiopulmonary bypass: A case report

2009 ◽  
Vol 25 (4) ◽  
pp. 208-210
Author(s):  
Karunakara Padhy ◽  
Suri Bhaskar Rama Narsimham ◽  
Pola Rabi Chandrahas ◽  
Goddu Sree Rama Chandra Murthy ◽  
Ponangi Venkata Satyanarayana
Keyword(s):  
Case Report ◽  
Cardiopulmonary Bypass ◽  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Tracheal Reconstruction

Acquired submitral aneurysms may be associated with mitral paravalvular leaks

2021 ◽  
pp. 021849232110063
Author(s):  
Palaparti Raghuram ◽  
Kothandam Sivakumar ◽  
Ejaz Ahamed Sheriff
Keyword(s):  
Cardiopulmonary Bypass ◽  
High Risk ◽  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Transcatheter Closure ◽  
Alternative Solution ◽  
Surgical Trauma ◽  
Ideal Solution ◽  
Repeat Surgery

Acquired submitral aneurysm after mitral valve replacement is caused by weakness of the annular tissues induced by inflammation, scarring, and ischemia from surgical trauma. The asynchronous stretch of the annulus caused by the submitral aneurysm may cause recurrent paravalvular leaks. In patients with acquired submitral aneurysms and paravalvular leaks, ideal solution is a repeat surgery to address both the aneurysm and the leak. However, when patients are at high risk for repeat surgeries on cardiopulmonary bypass through sternotomy, transcatheter closure of these paravalvar leaks may offer an alternative solution. Four such procedures in three patients are detailed in this report.

Acute Fulminant Hepatic Failure in a Woman Treated With Phenytoin and Trimethoprim-Sulfamethoxazole

2000 ◽  
Vol 124 (12) ◽  
pp. 1800-1803 ◽  
Author(s):  
Marius J-M. Ilario ◽  
Jose E. Ruiz ◽  
Constantine A. Axiotis
Keyword(s):  
Liver Injury ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Acute Hepatic Failure ◽  
Hepatic Necrosis ◽  
Rare Occurrence ◽  
Autopsy Findings ◽  
Massive Hepatic Necrosis

Abstract Massive hepatic necrosis following exposure to phenytoin and trimethoprim-sulfamethoxazole is a rare occurrence and to the best of our knowledge has not been reported previously. Acute hepatic failure following administration of trimethoprim-sulfamethoxazole has rarely been seen, and only 4 cases have been well documented pathologically. We report a case of acute liver failure in a 60-year-old woman following ingestion of phenytoin and trimethoprim-sulfamethoxazole concomitantly over a 9-day period. Autopsy findings revealed acute fulminant hepatic failure. This case demonstrates the effects of chemical-chemical interactions in the potentiation of hepatotoxicity of single agents and specifically illustrates the need for discontinuing trimethoprim-sulfamethoxazole in the presence of early liver injury.

scholarly journals Fetal Warfarin Syndrome – a case report

2022 ◽  
Vol 9 (1) ◽  
pp. 82-84
Author(s):  
Syed Sajid Hussain Shah ◽  
Bibi Aaliya
Keyword(s):  
Cardiac Surgery ◽  
Case Report ◽  
Family Planning ◽  
Plastic Surgery ◽  
Valve Replacement ◽  
Male Infant ◽  
Provisional Diagnosis ◽  
Initial Management ◽  
History Of ◽  
Nasal Hypoplasia

A two-month-old male infant presented with history of respiratory difficulty and got admitted with provisional diagnosis of pneumonia. On examination patient was having unilateral nasal hypoplasia and cyanosis with echocardiography showing truncus arteriosus. Detail history revealed that mother had valve replacement and she was taking warfarin during pregnancy. After initial management patient was referred to pediatric cardiac surgery and plastic surgery for further management. Parents were counseled regarding contraception and family planning.  

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