scholarly journals Treatment adherence of antiretroviral therapy among people living with HIV/AIDS

2017 ◽  
Vol 6 (3) ◽  
pp. 56-61
Author(s):  
B Sharma ◽  
K Joshi

Adherence to Antiretroviral therapy (ART)is a principle predictor for the success of Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome treatment. Highly Active Antiretroviral Therapy (HAART) has led to the reduction of mortality and the improvement of the quality of people living with HIV/AIDS. It has been estimated that at least 95% adherence with therapy is required to reduce HIV viral load. Non-adherence to treatment can lead to inadequate suppression of viral replication, continued destruction of CD4 cells, progressive decline in immune function and disease progression. The aim of the study is to assess treatment adherence of antiretroviral therapy among people living with HIV/AIDS at Seti Zonal Hospital, Kailali. A descriptive cross-sectional study was conducted among 160 people living with HIV/AIDS in ART Clinic, Seti Zonal Hospital, Kailali. Non-probability purposive sampling technique was used for data collection between 22/03/2071 to 02/04/2071. Informed consent was obtained prior collecting data from self-structured questionnaire using interview technique. Collected data were entered and analyzed by SPSS 17.0 and represented by using percentage, frequency, mean, standard deviation and chi- square test. Results: Among the respondents majority of them were “female” 85(53.1%) sex, from age group “31-45 years” 85 (53.1%), ethnicity “minority group/ Dalit” 76 (47.5%) and education “illiterate” 79 (50.3%). The mean adherence rate for one month was found to be 89.92%. Majority of the respondents were adherent to ART 96 (60%). Regarding non-adherence the major barrier was “forgetting” 52 (45.6%). There is statistically significant association between age of the respondents (p=0.04), ethnicity (p=0.03) and prescribed ARV regimen (p=0.02) with drug adherence. More than half of the respondents were adherent to ART. Among non-adherent, the most of them reported “forgetting to take drug”. Non adherence patient and family members can be addressed with proper counseling and motivation for their drug compliance. 

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Bekele Belayihun ◽  
Rahma Negus

Introduction. Antiretroviral Therapy has transformed HIV infection into a chronic manageable disease; it requires near perfect adherence rates (as high as 95%). In this study, we assessed antiretroviral treatment adherence rate and associated factors among people living with HIV in Dubti Hospital. Methods. A retrospective cross-sectional study design was conducted within February 1–30, 2014. All HIV-infected patients above the age of 18 years who took first line Antiretroviral Therapy were eligible for inclusion of the study. Adherence Scale was used for labeling patients as adherent or nonadherent. All HIV-infected patients record data were collected from the medical records, entered, and analyzed using Epi Info 7 and SPSS Version 20. Multivariable analysis was used to identify the relative effect of explanatory variables on low adherence rate. Results. A total of 370 patients aged 18 years and above, who started ART, were included in this study. The self-reported adherence rate of the patient on ART was 81.1%. Independent predictors of adherence were treatment duration. Conclusion. Adherence rate was associated with time to ART. That is, the longer they were on ART, the lesser they adhered.


2018 ◽  
Vol 4 (1) ◽  
pp. 43-52
Author(s):  
David Ufuoma Adje ◽  
Felicia Esemekiphorar Williams ◽  
Chukwuka Nicholas Bezugbe ◽  
Dauda Audi Dangiwa

Background:       Adherence to Highly Active Antiretroviral Therapy (HAART) is critical in achieving treatment goals, avoiding antimicrobial resistance, preventing treatment failure and improving the patient’s quality of life. Objectives: To assess the knowledge of antiretroviral therapy (ART) and adherence to antiretroviral (ARVs) medicines amongst People Living With HIV/AIDS (PLWHA) accessing care in two Nigerian Military HIV/AIDS Treatment sites. Methods: Four hundred patients on HAART who visited the study sites during the study period were recruited for the study using systematic random sampling method. A semi-structured, pretested, interviewer-administered questionnaire was used to obtain demographic details. Patients’ knowledge of HIV was assessed using an 8-item questionnaire while adherence was measured using the Simplified Medication Adherence Questionnaire (SMAQ). Results: The predominant age group was 31-40 years (46.4%). There were more females (69%) than males (31%). Only 45.5% answered knowledge questions correctly. The adherence level in this study was 64.0%. The major reasons cited for non-adherence included being away from home (23.6%), forgetfulness (17.1%), busy schedule (14%), need to conceal medication (12.7%) and feeling better (11.6%). Conclusion: Patients’ knowledge of ART and adherence to ARVs medicines were sub-optimal. Appropriate strategies to improve patients’ knowledge of ART and adherence to ARVs are recommended.


2008 ◽  
Vol 22 (4) ◽  
pp. 228-240
Author(s):  
Marilou Gagnon ◽  
Dave Holmes

The purpose of this article is to move beyond the biomedical standpoint in the field of HIV/AIDS in order to contribute to the recognition of lipodystrophy as a phenomenon that reaches far beyond its current definition as an unfortunate side effect of highly active antiretroviral therapy (HAART). This article hopes to demonstrate how theory, while remote to the clinical setting, can allow nurses to understand the experience of lipodystrophy as a social phenomenon and address it likewise in their practice. The specific aim of this article is to apply the concept of stigma to the experience of lipodystrophy in people living with HIV/AIDS. The objective of this theoretical piece is to fill the gaps in the way nurses address lipodystrophy in the clinical setting and to demonstrate the richness of Goffman’s concept of stigma (1963) in understanding the experience of lipodystrophy.


2016 ◽  
Vol 5 (56) ◽  
pp. 3872-3876
Author(s):  
Natarajan Kandasamy ◽  
Vijayanand Radhakrishnan ◽  
Ashokkumar Subramanian ◽  
Ravichandran Narayanan ◽  
Mohamed Kalifa Adbul Muthalif ◽  
...  

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