scholarly journals Effect of Posture in Intraocular Pressure, Comparison between Normal and Glaucomatous Subjects

2013 ◽  
Vol 11 (2) ◽  
pp. 21-23
Author(s):  
Ram Shrestha ◽  
Sagarika Patyal ◽  
Ramesh Bista ◽  
Sagar Rajkarnikar ◽  
Anu Gurung
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Armed Forces ◽  
Normal Tension Glaucoma ◽  
Cross Sectional Study ◽  
Control Group ◽  
Open Angle ◽  
Cross Sectional ◽  
Postural Changes

Introduction: Intraocular pressure (IOP) increases when changing from sitting to supine position with an average difference of 0.3 to 6.0mm of Hg. These postural changes of IOP have been found in normal persons, patients with ocular hypertension and normal tension glaucoma. The eye is relatively non-distensible, even small changes in the volume of aqueous humor may significantly change IOP. The increase in resistance in aqueous flow is thought to be the reason for higher IOP in supine compared to sitting position. The aim of this study was to analyze the effects of posture in intraocular pressure in normal and primary open angle glaucoma subjects. Methods: It was a prospective cross sectional study done in Armed Forces Medical College, Pune, between May, 2007 to May, 2009 with sample sized of 60 people (30 controls and 30 Primary open angle glaucoma). Patients underwent complete ocular examination. Two drops of Topical 4% lignocaine were instilled. IOP measurements were taken by Rebound tonometer in sitting and supine positions at 10 min and 30 min interval respectively. Results: Control group (40-76 yrs) and POAG group (40-78 yrs) were found to have a mean rise of IOP of 1.65 and 2 mm of Hg respectively from sitting to lying for 10min, and  a mean rise of 2.52 and 5.36 mm of Hg respectively from sitting to lying for 30min. Conclusions: The rise in IOP due to change of posture from sitting to supine positions was significantly higher in glaucomatous patients.Medical Journal of Shree Birendra Hospital; July-December 2012/vol.11/Issue2/21-23 DOI: http://dx.doi.org/10.3126/mjsbh.v11i2.7904 

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

scholarly journals Gait parameters, functional mobility and fall risk in individuals with early to moderate primary open angle glaucoma: a cross-sectional study

2018 ◽  
Vol 22 (5) ◽  
pp. 376-382 ◽  
Author(s):  
Henrique de Alencar Gomes ◽  
Bruno de Souza Moreira ◽  
Rosana Ferreira Sampaio ◽  
Sheyla Rossana Cavalcanti Furtado ◽  
Sebastião Cronemberger ◽  
...  
Keyword(s):  
Fall Risk ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Functional Mobility ◽  
Open Angle ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gait Parameters

scholarly journals Three Toxic Heavy Metals in Open-Angle Glaucoma with Low-Teen and High-Teen Intraocular Pressure: A Cross-Sectional Study from South Korea

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164983 ◽  
Author(s):  
Si Hyung Lee ◽  
Eun Min Kang ◽  
Gyu Ah Kim ◽  
Seung Woo Kwak ◽  
Joon Mo Kim ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Intraocular Pressure ◽  
South Korea ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Open Angle ◽  
Sectional Study ◽  
Toxic Heavy Metals ◽  
Cross Sectional

scholarly journals Circadian Variation of Ocular Perfusion Pressure in Primary Open Angle Glaucoma- A Cross-sectional Study

2021 ◽  
Author(s):  
Raheeba Pakeer Muhammed ◽  
Neeta Sidhan ◽  
Beena Thankappan
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Perfusion Pressure ◽  
Open Angle Glaucoma ◽  
Circadian Variation ◽  
Cross Sectional Study ◽  
Open Angle ◽  
Sectional Study ◽  
Ocular Perfusion Pressure ◽  
Cross Sectional ◽  
Ocular Perfusion

Introduction: Various haemodynamic factors have been implicated as pathophysiological mechanisms in Primary Open Angle Glaucoma (POAG) other than raised Intraocular Pressure (IOP). However, the exact relationship still remains unclear. Aim: To examine the circadian pattern of Blood Pressure (BP), IOP and Ocular Perfusion Pressure (OPP) with the aim of understanding their relationships in a cohort of patients with POAG. Materials and Methods: A cross-sectional study was conducted in which 44 cases of newly diagnosed, non-hypertensive patients with POAG were enrolled and categorised based on the severity of glaucoma. Recording of BP and IOP were done every 4th hourly during a 24 hour hospital stay. The Mean OPP (MOPP) was calculated as 2/3×Mean Arterial Pressure (MAP)-IOP. Systolic OPP (SOPP) was calculated as Systolic BP-IOP and Diastolic OPP (DOPP) was calculated as Diastolic BP-IOP. The diurnal, nocturnal and 24 hour fluctuations were derived from the difference between the highest and lowest values within each period. Data was analysed using Statistical Package for the Social Sciences (SPSS) version 16.0. Univariate and multivariate regression analysis of the variables with age and severity of POAG were performed Results: Significant positive correlation of the nocturnal fluctuations in MAP (r=0.533), SOPP (r=0.835), DOPP (r =0.768), MOPP (r=0.685) and 24 hour fluctuation in MOPP (r=0.636) were noted with severity of glaucoma on multivariate analysis. No significant correlation of these parameters with age was noted on multivariate analyses. Conclusion: Nocturnal dip in OPP was an important observation among patients with POAG, potentially contributing to its pathophysiology.

scholarly journals A CROSS-SECTIONAL STUDY TO EVALUATE THE USEFULNESS OF ‘PRESSURE TO CORNEA INDEX’ IN PREDICTION OF PRIMARY OPEN ANGLE GLAUCOMA

2018 ◽  
Vol 7 (01) ◽  
pp. 47-49
Author(s):  
Pandiyaraj Saravanasankar ◽  
Anbazhaghan Amudha ◽  
Srinivasan Muralikrishnan ◽  
Reethysreekumar Sruthi ◽  
Rajan Saranya ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Open Angle ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Progressive spectacle correction in patients with ametropia and primary open-angle glaucoma

The Eye ◽  
2019 ◽  
Vol 125 (2019-1) ◽  
pp. 6-12
Author(s):  
Irina Gndoyan ◽  
Natalya Kuznetsova ◽  
Alexander Derevyanchenko
Keyword(s):  
Intraocular Pressure ◽  
Aqueous Humor ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Aqueous Humor Outflow ◽  
Vision Correction ◽  
Spectacle Correction

Purpose: To determine the role that progressive spectacle lenses play in intraocular pressure compensation and stabilization of the glaucomatous process in patients with primary open-angle glaucoma (POAG) combined with presbyopia and refractive errors. Material and methods. 29 patients (53 eyes) aged 43 to 67 years with I-II stage POAG and a certain type of refractive error were enrolled into study. All patients had intraocular pressure (IOP) compensated to the target level on medication. Patients of the main group (17 people, 32 eyes) used universal progressive spectacle lenses with optimized surface. The patients of the control group (12 people, 21 eyes) used separate monofocal glasses for near and distance vision as a method of ametropia correction. Visual acuity test, refractometry, pneumotonometry, tonography, automated static perimetry were applied for monitoring the patients. The measurements were taken before spectacle correction and a year after its prescription. Results. A decrease of IOP (p=0.01) and an increase of the aqueous humor outflow coefficient (p<0.01) were determined after one year use of the recommended type of vision correction in the main group, whereas in the control group there was an increased level of IOP (p<0.05) and a reduced aqueous humor outflow coefficient (p<0.2). Conclusion. The use of progressive spectacle lenses as a method of permanent vision correction reliably reduces IOP and improves the aqueous humor outflow in patients with early-stage POAG. The absence of negative visual field dynamics indicates the stabilization of the glaucomatous process.

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