scholarly journals Sex Ratio at Birth: A Retrospective Audit of the Birth Records of a Nigerian Hospital

2015 ◽  
Vol 10 (1) ◽  
pp. 85-88
Author(s):  
AN Onyiriuka ◽  
EM Ikeanyi
Keyword(s):  
Sex Ratio ◽  
Birth Order ◽  
Maternal Age ◽  
Sex Ratio At Birth ◽  
Offspring Sex Ratio ◽  
North West ◽  
Benin City ◽  
Retrospective Audit ◽  
Offspring Sex ◽  
Catholic Hospital

Aims: The aim was to determine the sex ratio at birth in St Philomena Catholic Hospital (SPCH), Benin City, south-south, Nigeria and to assess its relationship with birth order and maternal age. Methods: In this retrospective cohort study, the records of all deliveries at St Philomena Catholic Hospital (SPCH), Benin City, Nigeria between 1st January, 2005 and 31st December, 2014 (10 years) were retrieved and analyzed. Stillbirths and infants with ambiguous genitalia were excluded in the analysis. Results: The total number of live-births during the 10-year period under review was 13,702 and these consisted of 7,007 males and 6,695 females, resulting in a sex ratio of 104.7:100 (approximately 1.05) at birth. The yearly sex ratios varied from 1.01 to 1.14. The maternal age and the birth order significantly influenced offspring sex ratio at birth (p < 0.001). The highest sex ratio was found among third-birth-order offspring and the lowest was found among offspring of fifth-birth order and above. Offspring of mothers aged 25-29 years had the highest sex ratio and those of mothers aged 40 years and above had the lowest sex ratio. Conclusions: The sex ratio at birth in south-south Nigeria is comparable to values obtained from south-west Nigeria but lower than that obtained from north-west Nigeria. The birth order and maternal age influenced the offspring sex ratio at birth.  

scholarly journals Preconception Vitamin D Status and Offspring Sex Ratio Among Women with Prior Pregnancy Loss (OR17-05-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Alexandra Purdue-Smithe ◽  
Keewan Kim ◽  
Carrie Nobles ◽  
Enrique Schisterman ◽  
Karen Schliep ◽  
...  
Keyword(s):  
Vitamin D ◽  
Sex Ratio ◽  
Live Birth ◽  
Low Grade ◽  
Vitamin D Status ◽  
Sex Ratio At Birth ◽  
Offspring Sex Ratio ◽  
Fetal Survival ◽  
Offspring Sex ◽  
Low Grade Inflammation

Abstract Objectives Experimental data indicate that maternal exposure to factors known to alter inflammatory milieu may be specifically harmful to the conception or survival of male fetuses. Indeed, in a recent clinical trial, preconception administration of low dose aspirin versus placebo restored the skewed sex ratio at birth among women with elevated inflammation, providing direct evidence of this phenomenon in humans. However, it is unknown whether other factors associated with inflammation, such as vitamin D status, are associated with offspring sex ratio at birth. Our objective was thus to evaluate the association of preconception serum 25-hydroxyvitamin D levels [25(OH)D] and male live birth among 1228 reproductive-age women with a history of 1–2 prior losses who were enrolled in the Effects of Aspirin in Gestation and Reproduction trial between 2007–2011. Methods We estimated RRs and 95% CIs for male live birth according to 25(OH)D sufficiency (≥75 vs. <75 nmol/L) using generalized estimating equations of log-binomial regression with robust standard errors. Results Among the 1086 women who completed follow-up, the proportion of live-born males was 24% (n = 136) and 30% (n = 156) in the 25(OH)D insufficient and sufficient groups, respectively. After adjustment for age, race/ethnicity, and other factors, women in the 25(OH)D sufficient group were 23% (95% CI: 1.01, 1.49) more likely to have a live-born male infant compared to the insufficient group. Associations were stronger among women with elevated versus low levels of high sensitivity C-reactive protein (>1.95 ng/mL: RR: 1.41; 95% CI: 0.99, 2.00 versus ≤1.95 ng/mL RR: 1.11; 95% CI: 0.88, 1.41), a marker of systemic low-grade inflammation. Conclusions Preconception vitamin D status was associated with male live birth, particularly among women with low-grade inflammation. These data suggest that maternal vitamin D sufficiency may mitigate maternal inflammation that would otherwise be detrimental to male fetal survival. Funding Sources Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD.

scholarly journals Sex ratio at Birth in a Tertiary Care Hospital in Western Nepal are the Trends Changing?

2016 ◽  
Vol 36 (1) ◽  
pp. 68-71
Author(s):  
Shreyashi Aryal ◽  
Balkrishna Kalakheti
Keyword(s):  
Sex Ratio ◽  
Gender Discrimination ◽  
Maternal Age ◽  
Tertiary Care ◽  
College Teaching ◽  
Care Hospital ◽  
Sex Ratio At Birth ◽  
Female Population ◽  
Live Births ◽  
Retrospective Audit

Introduction: Sex ratio at birth remains unchanged in absence of human intervention. A tendency of skewing towards males is seen in Asian population attributable to various reasons, foremost being abortions. The decreasing number of female population is a form of gender discrimination and has serious implications for both sexes in the future. The purpose of this study was to analyze the trends of sex ratio at birth among deliveries at Lumbini Medical College Teaching Hospital, Palpa, Nepal over the past eight years.Materials and Methods: A retrospective audit of deliveries from 1st January 2008 to 31st December 2015 was carried out. Sex ratio at birth was calculated and its relationship with maternal age, birth order and number of previous abortions was analyzed.Results: The total number of live-births during the study period was 9394 consisting of 5008 male and 4350 female with an overall sex ratio at birth of 112.6. Every year, there was an increasing trend in total number of live births and sex ratio at birth. The number of male births increased with increase in parity but there was no statistical difference seen between maternal age, parity and number of abortions for male and female births.Conclusion: The sex ratio at birth in hospital deliveries is unbalanced with inclination towards male, more so in women with high parity. Additional research exploring the reason for increase in male births is needed, so that potential programs which can reverse this trend can be implemented.J Nepal Paediatr Soc 2016;36(1):68-71

Maternal age, paternal age, and litter size interact to affect the offspring sex ratio of German Shepherd dogs

2019 ◽  
Vol 135 ◽  
pp. 169-173
Author(s):  
Anna Carolina Lopes Martins ◽  
Marília Andreia Vaz ◽  
Max Mendes Macedo ◽  
Renato Lima Santos ◽  
Conrado Aleksander Barbosa Galdino ◽  
...  
Keyword(s):  
Sex Ratio ◽  
Litter Size ◽  
Maternal Age ◽  
Paternal Age ◽  
German Shepherd ◽  
Offspring Sex Ratio ◽  
Offspring Sex

Offspring sex ratio in moose Alces alces in relation to paternal age: an experiment

2004 ◽  
Vol 10 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Bernt-Erik Sæther ◽  
Erling J. Solberg ◽  
Morten Heim ◽  
John E. Stacy ◽  
Kjetill S. Jakobsen ◽  
...  
Keyword(s):  
Sex Ratio ◽  
Alces Alces ◽  
Paternal Age ◽  
Offspring Sex Ratio ◽  
Offspring Sex
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