scholarly journals Effect of adrenalectomy, pup removal, hypophysectomy and hydrocortisone acetate on mammary gland nucleic acid content in the near term pregnant rat

1975 ◽  
Author(s):  
Juanita Caroyln Barrena
1983 ◽  
Vol 212 (1) ◽  
pp. 149-153 ◽  
Author(s):  
M E Brosnan ◽  
R Farrell ◽  
H Wilansky ◽  
D H Williamson

Starvation caused a marked increase in putrescine content in mammary gland of lactating rats, together with a marked decrease in activity of ornithine decarboxylase and appearance of measurable ornithine decarboxylase antizyme. 2. Refeeding for 5 h caused disappearance of free antizyme and ornithine decarboxylase activity returned to the value in fed animals. Putrescine concentration remained elevated. 3. There was no significant change in nucleic acid content of mammary gland from starved rats, but spermidine and spermine contents increased significantly. 4. Refeeding for 5 h returned the spermidine content of mammary glands to ‘fed’ values, and significantly decreased the content of spermine, although it did not reach control values. Thus changes in polyamine content of mammary gland in starved rats are clearly dissociated from changes in either RNA content or activities of polyamine-synthetic decarboxylases. 5. Starvation caused a fall in the content of spermidine in liver, with no change in spermine content. Refeeding for 5 h returned the spermidine content to ‘fed’ values.


1965 ◽  
Vol 33 (2) ◽  
pp. 185-194 ◽  
Author(s):  
K. ÔTA ◽  
A. YOKOYAMA

SUMMARY Foster litters were given to lactating rats whose own litters had been removed 3, 5 or 9 days previously. Lactation was restored in all groups by this re-suckling procedure within a relatively short period. The restoration of lactation became more difficult as the interval between the removal of the original litters and the application of the foster litters increased. Changes in the nucleic acid content of the mammary gland after re-suckling were investigated in the rats whose litters were removed for 3 days before re-suckling. Both the DNAP content of the gland and its weight increased steadily in proportion to the length of the period of re-suckling, so that a fairly constant DNAP concentration was maintained in the tissue. The RNAP content and the RNAP:DNAP ratio, on the other hand, increased abruptly at about the time when milk secretion was initiated by re-suckling. The DNAP content continued to increase even after the onset of restored milk secretion. These results suggest that milk secretion after re-suckling began before full restoration of the tissue structure and that growth of the glandular tissue took place concurrently with milk secretion.


1971 ◽  
Vol 54 (1) ◽  
pp. 113-116
Author(s):  
B.N. Gupta ◽  
E.M. Convey ◽  
R.F. Langham ◽  
G.H. Conner

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