ABSTRACT:
PURPOSE:
To study the changes in Ganglion Cell Complex as measured on OCT after
phacoemulsification with intra ocular lens implantation.
STUDY DESIGN:
Quasi experimental study
PLACE AND DURATION OF STUDY:
Department of Ophthalmology, Lahore General Hospital, Lahore from 1-3-2017 to 30-4-2018
MATERIALS AND METHODS:
Ethical approval of the study was obtained from ‘’Ethical Review Committee’’ of Lahore General
Hospital, Lahore. Patients presenting to the Eye OPD Lahore General Hospital were assessed for
inclusion and exclusion criteria. All patients (n=64) diagnosed with cataract requiring surgery
were included in study. Patients having any coexisting ocular pathology hindering the OCT
measurement i.e. Corneal opacity, Vitreous hemorrhage, Retinal detachment were excluded
from study. Retinal Ganglion Cell Complex thickness was measured in Superior, Inferior,
Supero-Nasal, Supero-Temporal, Infero-Nasal and Infero-Temporal quadrants. Besides that
Signal Strength on OCT was also documented. Pre-Operatively, Visual acuity was measured and
OCT performed and the findings were recorded on a designed proforma. Post-Operatively, the
patients were called for follow-up after one month at which time Visual acuity was again
measured and OCT performed and findings recorded in the proforma. All the surgeries were
performed by single surgeon.
RESULTS:
The thickness of Ganglion Cell Complex increased significantly (p<0.001) one month after
cataract surgery.
CONCLUSION:
Cataract surgery does affect the measurement of Retinal Ganglion Cell Complex thickness on
OCT.
Retinal ganglion cell complex changes using spectral domain optical coherence tomography in diabetic patients without retinopathy